scholarly journals Renal cell carcinoma in a horseshoe kidney

2009 ◽  
Vol 56 (1) ◽  
pp. 97-99 ◽  
Author(s):  
J. Hadzi-Djokic ◽  
V. Colovic ◽  
T. Pejcic ◽  
D. Dragicevic
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Horseshoe Kidney ◽  
Tissue Mass ◽  
Abdominal Incision ◽  
Surgical Interventions ◽  
History Of ◽  
Hypervascular Tumor ◽  
The Right

A case of an adenocarcinoma within a horseshoe kidney (HK) is presented. Male patient presented with a history of a painless hematuria. A contrast enhanced magnetic resonance (MR) scan showed a horseshoe kidney. A large soft tissue mass was also noted on the right side. Kidney was receiving supply from two arteries on the left side and one at the right side. Angiography of the right renal artery demonstrated hypervascular tumor staining. The kidney was approached through midline abdominal incision, and a right heminephrectomy was performed. The histopathology examination showed pT2, grade 2 renal cell carcinoma. To conclude, angiography is indispensable for guiding surgical interventions.

scholarly journals Pediatric Papillary Renal Cell Carcinoma in a Horseshoe Kidney: A Case Report with Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Abelardo Loya-Solis ◽  
Lucía Alemán-Meza ◽  
Luis Carlos Canales-Martínez ◽  
Rodolfo Franco-Márquez ◽  
Alim Adriana Rincón-Bahena ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Horseshoe Kidney ◽  
Papillary Renal Cell Carcinoma ◽  
Renal Tumors ◽  
Eosinophilic Cytoplasm ◽  
Abundant Eosinophilic Cytoplasm ◽  
History Of ◽  
The Right

Renal cell carcinoma is the most common malignancy of the kidney in adults. In children, however, it only accounts for an estimated 1.8 to 6.3% of all pediatric malignant renal tumors. Papillary renal cell carcinoma is the second most common type of renal cell carcinoma in children. We present the case of a 12-year-old boy with a 2-month history of abdominal pain, unexplained weight loss, and gross hematuria. Computed tomography revealed a horseshoe kidney and a well-defined mass of 4 cm arising from the lower pole of the right kidney. Microscopically the tumor was composed of papillae covered with cells with abundant eosinophilic cytoplasm and high-grade nuclei with prominent nucleoli. Immunohistochemistry was performed; EMA, Vimentin, and AMACR were strongly positive while CK7, CD10, RCC antigen, TFE3, HMB-45, and WT-1 were negative. Currently, 10 months after the surgical procedure, the patient remains clinically and radiologically disease-free.

scholarly journals Laparoscopic partial nephrectomy for renal cell carcinoma in a horseshoe kidney

2014 ◽  
Vol 8 (11-12) ◽  
pp. 918 ◽  
Author(s):  
Tarik Benidir ◽  
Tiago Jacometo Coelho de Castilho ◽  
Guilherme Rodrigo Lobo Cherubini ◽  
Murilo De Almeida Luz
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Partial Nephrectomy ◽  
Renal Cell ◽  
Laparoscopic Approach ◽  
Horseshoe Kidney ◽  
Renal Calculi ◽  
Clinical Situation ◽  
Laparoscopic Partial Nephrectomy ◽  
The Right

Horseshoe kidney has an incidence rate ranging from 1 in 400 to 1 in 1000, with a 2:1 ratio in men. It also has a predilection for chromosomal aneuploidies. From a pathophysiology standpoint, this anomaly occurs during the second to sixth week of gestation when the inferior portion of the metanephric blastema fuses to form an isthmus, commonly in the lower renal pole (90%). As a result of this fusion, the kidney may not bypass the inferior mesenteric artery and is impeded in its ascent. With an aberrant anatomical orientation and location, complications arise including hydronephrosis, renal calculi and a twofold risk of Wilms tumour. Despite these findings, the association of renal cell carcinoma (RCC) within a horseshoe kidney is extremely rare and fewer than 200 cases have been described. Therapeutically speaking, partial nephrectomies are the gold standard of treatment for renal tumours smaller than 4 cm in diameter, with a growing indication to accomplish this procedure by laparoscopic or robotic means. We report a case of an asymptomatic 58-year-old male with an incidental computed tomography scan finding of a 4-cm solid mass in the right moiety of a horseshoe kidney. He was treated by laparoscopic partial nephrectomy. There have only been 2 other reported cases to our knowledge on a laparoscopic partial nephrectomy in a horseshoe kidney for RCC. We believe that, in experienced hands, the laparoscopic approach may be used successfully for this clinical situation.

scholarly journals Solitary Intrathyroid Metastasis Occurring 23 Years after Resection of Renal Cell Carcinoma

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
X. Vandemergel
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Needle Aspiration ◽  
Thyroid Lobe ◽  
Aspiration Cytology ◽  
History Of ◽  
Right Lobe ◽  
Needle Aspiration Cytology ◽  
The Right

A case of solitary intrathyroid metastasis is described in a 60-year-old male patient. He had a history of renal cell carcinoma classified as T1b resected 23 years earlier. A mass was palpable in the right thyroid lobe. Ultrasound showed a hypoechoic polylobular nodule with intense vascularisation in the right lobe. Fine needle aspiration cytology was normal, but thyroidectomy was performed due to mass enlargement, the ultrasound pattern, and the oncological history. Histological examination revealed the presence of an intrathyroid metastasis of renal cell carcinoma. The bone scan and thoracoabdominal CT scan were normal. Postoperative care was uneventful.

scholarly journals Report of a Rare Case of Sarcomatoid Renal Cell Carcinoma

2014 ◽  
Vol 13 (3) ◽  
pp. 80-83
Author(s):  
Mohammad Ismail Hossain ◽  
Imtiaz Ahmed ◽  
Pradip Bhattacharjee ◽  
M Sahab Uddin Ahamad ◽  
Zillur Rahman
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Fibrous Histiocytoma ◽  
Renal Tumors ◽  
Large Growth ◽  
Sarcomatoid Renal Cell Carcinoma ◽  
History Of ◽  
The Right ◽  
Immunohistological Analysis

A 50 years old non-smoker female with the history of right flank pain and hematuria surgically treated with right sided radical nephrectomy. Macroscopically it showed a large growth located at the lower pole of the right kidney. Histologically the tumor was composed of exuberant sarcomatous elements predominantly malignant fibrous histiocytoma like pattern and  diagnosed as sarcomatoid renal cell carcinoma. There was no scope for immunohistological analysis of that tumor in our setup. It is important to recognize the sarcomatoid component in the renal tumors because of its aggressive behavior and adverse prognosis. We report herein a case of sarcomatoid renal cell carcinoma histomorphogically.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i3.21039

scholarly journals Renal cell carcinoma of horseshoe kidney

2020 ◽  
pp. 72-72
Author(s):  
Milomir Tufegdzic ◽  
Vladimir Vasic ◽  
Jovan Hadzi-Djokic
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Partial Nephrectomy ◽  
Renal Cell ◽  
Horseshoe Kidney ◽  
Ct Urography ◽  
Lower Pole ◽  
Macroscopic Hematuria ◽  
Patient Reported ◽  
The Right

Introduction. Horseshoe kidney is the most common developmental disorder of the urinary system, which involves an anomaly of kidney fusion, and occurs in 3% of the population. Kidneys are most often connected at the lower poles by fibrous or parenchymal isthmus. Renal cell carcinoma (RCC) is the most common tumor of the horseshoe kidney. Treatment involves surgical treatment that includes heminephrectomy or partial nephrectomy with different approaches. We report a case of RCC of a horseshoe kidney, located on lower pole and isthmus. Case outline. A sixty-eight-year-old patient reported to the urologist due to intermittent painless macroscopic hematuria. CT urography revealed the presence of a tumor on the right kidney measuring 85 ? 90 ? 60 mm, with radiological characteristics of RCC, which covered the entire lower pole of the kidney towards the isthmus. Angiography finding indicated thickened isthmus with pronounced malformation of vascular structures. The right heminephrectomy was performed with resection of the isthmus from 15 mm to healthy tissue. The isthmus was sutured in two layers with a catgut suture. Subsequently, hilar, paracaval, and interaorthocaval lymphadenectomy were performed. The pathohistological finding indicated a tumor of renal cell origin while the resection line was free of tumor tissue, as were the lymph nodes Conclusion. RCC is the most common neoplasm of the horseshoe kidney. Treatment is surgical and involves open or laparoscopic heminephrectomy or partial nephrectomy with a transperitoneal or extraperitoneal approach.

Case 4.26

2014 ◽  
pp. 236-237
Author(s):  
Christine U. Lee ◽  
James F. Glockner
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Left Kidney ◽  
Arterial Phase ◽  
Pancreatic Body ◽  
History Of ◽  
Venous Phase ◽  
The Right ◽  
T2 Weighted Images

78-year-old man with a history of renal cell carcinoma Axial fat-suppressed FRFSE T2-weighted images (Figure 4.26.1) reveal multiple mildly hyperintense lesions in the pancreatic body and head. Arterial phase (Figure 4.26.2) and venous phase (Figure 4.26.3) postgadolinium 3D SPGR images also demonstrate multiple hypervascular pancreatic lesions. Notice also the absent left kidney (from a nephrectomy) and multiple solid enhancing lesions in the right kidney....

scholarly journals Polycythemia with Renal Cell Carcinoma and Normal Erythropoietin Level

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Jonathan Kopel ◽  
Pranav Sharma ◽  
Irfan Warriach ◽  
Sriman Swarup
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Chronic Obstructive ◽  
Cell Renal Cell Carcinoma ◽  
Obstructive Pulmonary Disease ◽  
Abdominal Aortic ◽  
Blood Clots ◽  
History Of ◽  
The Right

A 61-year-old obese Caucasian male with past medical history of smoking, hypertension, chronic obstructive pulmonary disease (COPD), and sleep apnea presented to the hematology clinic with polycythemia. Despite the newly-diagnosed polycythemia, the patient denied any significant symptoms or history of blood clots. Further evaluation with computerized tomography (CT) and ultrasound showed a large renal mass suspicious for renal cell carcinoma of the right kidney. An incidental abdominal aortic aneurysm (AAA) measuring was also appreciated on imaging. Subsequent histological sections of the tumor showed cell renal cell carcinoma. Though previously reported, the concomitant finding of an AAA with renal cell carcinoma with a normal erythropoietin levels is surprising. Given the surgical complications associated with concomitant conditions with renal cell carcinoma, further investigation into paraneoplastic syndromes secondary to renal cell carcinoma remains open to investigation.

scholarly journals Enormous primary renal diffuse large B-cell lymphoma: A case report and literature review

2019 ◽  
Vol 47 (6) ◽  
pp. 2728-2739
Author(s):  
Xu Cheng ◽  
Zhichao Huang ◽  
Daiqiang Li ◽  
Yinhuai Wang
Keyword(s):  
Computed Tomography ◽  
Renal Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Multidisciplinary Team ◽  
Renal Cell ◽  
Team Management ◽  
History Of ◽  
The Right

Introduction Primary renal lymphoma is a rare malignant lymphoma that is difficult to differentiate from renal cell carcinoma. Positron emission tomography/computed tomography and image-guided percutaneous biopsy are valuable tools for diagnosis. Case report A 64-year-old woman presented with a 2-year history of repeated right waist pain and a 1-month history of nausea, vomiting, and frequent and urgent urination. A computed tomography scan showed a huge mass that was initially considered to be renal cell carcinoma at the upper pole of the right kidney. The mass had invaded the renal pelvis, narrowed the right renal artery, and constricted the inferior vena cava and liver. Postoperative examination of the tumor confirmed lymphoma. We herein present this case and its multidisciplinary team management. Conclusion Multidisciplinary team management is efficient for preoperative assessment and surgery in difficult and high-risk cases. Based on our literature review, we suggest biopsy before chemotherapy whenever possible. Chemotherapy can be implemented after surgery for better survival outcomes.

Clinical characteristics and treatments of hereditary leiomyomatosis renal cell carcinoma: two case reports and literature review

2020 ◽  
Author(s):  
Dalin Feng ◽  
Mingshuai Wang ◽  
Xiaodong Zhang ◽  
Jianwen Wang
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Female Patient ◽  
Male Patient ◽  
Renal Cell ◽  
Clinical Characteristics ◽  
Genetic Test ◽  
Enhanced Ct ◽  
The Right ◽  
Hereditary Leiomyomatosis

Abstract Background The objective of this study is to discuss clinical characteristics and treatments of hereditary leiomyomatosis renal cell carcinoma on the basis of 2 cases and to review recent literature, in order to present medical advances. Methods A 29-year old male patient came to our hospital because of a huge tumour on the right kidney. Enhanced CT showed that the tumour was about 15.5*10.5 cm, and was considered to be malignant. Another case was a 38-year old female patient. She complained was found to have a right kidney tumour in a routine physical examination. Enhanced CT showed an early-stage tumour of about 4.3*3.7 cm on the lower pole of the right kidney. The male patient underwent open radical nephrectomy and the female patient underwent laparoscopic radical nephrectomy and extensive retroperitoneal lymph node dissection. The two patients underwent genetic testing and were diagnosed as having hereditary leiomyomatosis with renal cell carcinoma. Results The postoperative pathology in both patients revealed type 2 papillary renal cell carcinoma but with different prognosis. The male patient suffered multiple metastasis 10 months post-operation. The metastatic tumour of the abdominal wall was resected to confirm recurrence and hereditary leiomyomatosis renal cell carcinoma was diagnosed by the genetic test. While the female patient had a specific family history and uterine leiomyomas, the genetic test helped us to identify hereditary leiomyomatosis renal cell carcinoma pre-operation. Because of the early diagnosis and timely treatment, the female patient was considered to have a good prognosis. Conclusion Hereditary leiomyomatosis renal cell carcinoma is a rare hereditary disease resulting from FH gene mutation. There are currently no effective treatments.Our cases demonstrate that hereditary leiomyomatosis renal cell carcinoma is a very aggressive disease. Early screening and surveillance are recommended for patients with a family history or who are at risk of hereditary leiomyomatosis renal cell carcinoma. Surgical and palliative therapy still play an important role in clinical treatment.

scholarly journals Metastatic renal cell carcinoma extending to the left atrium through the inferior pulmonary vein

2021 ◽  
Author(s):  
Alan G Dawson ◽  
Cathy J Richards ◽  
Leonidas Hadjinikolaou ◽  
Apostolos Nakas
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Left Atrium ◽  
Pulmonary Vein ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Pulmonary Veins ◽  
Lower Lobe ◽  
Inferior Pulmonary Vein ◽  
The Right

Abstract Metastatic renal cell carcinoma with involvement through the pulmonary veins to the left atrium is very rare. We report the case of a 70-year-old male with metastatic renal cell carcinoma to the right lower lobe of the lung abutting the inferior pulmonary vein with extension to the left atrium without pre-operative evidence. Surgical resection was achieved through a posterolateral thoracotomy. Lung masses that abut the pulmonary veins should prompt further investigation with a pre-operative transoesophageal echocardiogram to minimize unexpected intraoperative findings.

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