scholarly journals Autotransplantacija slezine

2002 ◽  
Vol 49 (3) ◽  
pp. 101-106 ◽  
Author(s):  
S. Knezevic ◽  
D. Stefanovic ◽  
M. Petrovic ◽  
Z. Djordjevic ◽  
Slavko Matic ◽  
...  

Auto transplantation of the spleen can be performed in the patients with traumatic rupture of the spleen, in whom spleen could not be conserved in the other way. The right indication for this method is isolated rupture of the spleen (concvasation or complete devascularisation). This method is not recommended in the endangered patients, patients with previous disease of the spleen as well as in the patients with the perforation of the other abdominal organs at the same time. Auto transplantation was performed in 12 patients with isolated splenic rupture and hematoperitoneum, 11 men and one woman. The majority of patients are younger. In 8 patients, autotransplantat was placed into big omentum, in three into lipomatous tissue surrounding left kidney, and in one into anterior abdominal wall. In all the patients from this group, following analysis were taken: MCV (middle volume of erythrocytes), HTC, Hb, Le, Glucose, urea, creatinin, sodium, potassium, alkali phosphatasis, target cells, Howell Jolly's bodies, Heinz's bodies, IgG, IgA, igM, C3, C4, T3, T4, T8, B, segmentated, eosinophiles, lymphocytes, reticulocytes, thrombocytes, fibrinogen, PT, APTT, aggregation of thrombocytes and aggregation of thrombocytes on collagen. The same parameters were taken in 12 patients with surgery similar to splenectomy and in 12 after splenectomy. After splenectomy, there was decrease of the immunologic defending abilities of the organism because of the loss of the clirens function of the spleen, decreased level of the opsonines and tutsin, which leads to the impaired phagocytosis, decreased concentration of IgM and T and B lymphocytes, while in patients after auto transplantation the results were physiological. The most important thing in the assessment of the function of the autotransplantated spleen is scintigraphic investigation using 99mTc-denaturated red blood cells. In our study, auto transplant function was assessed in 10/12 patients by scintigraphy. Five years after surgery no one patient was proved to have postsplenectomic sepsis.

2010 ◽  
Vol 5 (6) ◽  
pp. 586-590 ◽  
Author(s):  
Balaji Srinivas ◽  
Vivek Joseph ◽  
Geeta Chacko ◽  
Vedantam Rajshekhar

Spinal extradural cysts do not normally present as a visible paraspinal mass or cause compression of the abdominal organs. The authors describe the case of a 9-month-old boy with multiple spinal extradural cysts. The largest of these cysts was along the right L-2 nerve root with significant extraspinal extension resulting in a visible slow-growing swelling in the right paraspinal region and radiological evidence of compression of the right kidney with hydronephrosis. Another large cyst along the left T-12 root caused radiologically evident compression of the left kidney but to a lesser degree. The patient also had monoparesis of the left lower limb and phenotypic features of Noonan syndrome. The authors performed marsupialization of the cysts, as well as repair of the fistula between the subarachnoid space and the cyst on the right side along the L-2 root and on the left side along the T-12 root. At 1-year follow-up, there was no paraspinal mass and the lower limbs exhibited normal power. Magnetic resonance imaging confirmed marked reduction in the size of the cysts and relief of the renal compression. To the authors' knowledge, their patient is the youngest reported in literature to have a spinal extradural cyst and also the first with the cyst presenting as a paraspinal mass.


2016 ◽  
Vol 63 (3) ◽  
pp. 251-254
Author(s):  
Maria Daniela Tănăsescu ◽  
◽  
Marcel Pălămar ◽  
Mihai Ovidiu Comşa ◽  
Alexandru Mincă ◽  
...  

Objectives. Renal artery stenosis, as main cause of renovascular secondary hypertension, is mainly caused by atherosclerosis of large vessels and is clinically characterized by resistant or malignant hypertension, impacting the kidney function to various degrees. The present article brings into attention the case of a patient which developed renal artery stenosis on the left kidney, the same condition occurring 12 years later on the right kidney. Material and method. Our patient was initially diagnosed at the age of 48 with complete occlusion of the left renal artery, for which left nephrectomy was performed, while the right artery was normal. Twelve years later she presents with renal artery stenosis on the right kidney, which is treat by stent-angioplasty. Results. After surgery, the patient’s evolution was positive, with amelioration of the laboratory values, in parallel to the arterial blood pressure. Discussions. The probability that, in the moment of diagnosis of renal artery stenosis with progressive evolution to occlusion caused by atherosclerosis, the other artery would be normal, both seen by ultrasonography and angiography, while years later to develop stenosis, is minimal. Up to present, the literature holds little evidence of such similar cases. Conclusions. In the particular case of patients that were diagnosed with severe renal artery stenosis of atherosclerotic origin and had only one of the arteries affected, it is necessary to keep a permanent monitoring, justified by the risk of development of the same pathology to the other artery


Spontaneous non-traumatic rupture of the spleen in the setting of Legionnaires’ disease is very uncommon but a life-threatening condition. The splenic rupture can present within a few days after symptom onset with significant hypotension with drop in haemoglobin along with left side upper quadrant pain. Most of the cases described in the previous literature have presented within 0-11 (mean 4) days of the pneumonia but this case we are reporting presented after 3 weeks after being treated with Legionella pneumonia. The case also highlights an atypical presentation and emphasises the need to maintain a low threshold for diagnosis especially in resource constrained setting so that patient can be transferred at the earliest to a centre where appropriate corrective measures including surgery can be safely undertaken. Keywords: splenic rupture, pneumonia, hypovolemic shock


2020 ◽  
Vol 44 (5) ◽  
pp. 1063-1069
Author(s):  
Paul CARDENIO ◽  
Jezie ACORDA ◽  
Emilia LASTICA-TERNURA

This study was conducted to determine the ultrasonographic features of the liver, gallbladder, spleen, kidneys, and urinary bladder of 24 apparently healthy male and female long-tailed macaques (LTM) and the correlations of organ measurements with body weight and crown–rump length. The animals were grouped into 12 males and 12 females. Examination was performed in sedated LTM using an ultrasound machine with 6.0 MHz microconvex scanner. Ultrasound appearance, dimensions, and echotexture of the liver, gallbladder, kidneys, spleen, and urinary bladder were evaluated. The results showed that there were no sex-related differences in echo mean values, thickness, and length of the selected abdominal organs. The liver was hypoechoic to isoechoic with the right renal cortex, while spleen was isoechoic to hyperechoic to left renal cortex. Spleen was hypoechoic to isoechoic to the liver. Gallbladder and urinary bladder had hypoechoic to hyperechoic thin wall with anechoic lumen. There was a statistically significant and moderate positive correlation between the volume of the left kidney and body weight. The right kidney volume was greater than the left kidney and the total renal volume had a statistically significant and moderate positive correlation with body weight. This study established the reference values for ultrasonographic features of selected abdominal organs of rescued LTM.


2018 ◽  
Vol 99 (4) ◽  
pp. 722-729
Author(s):  
S B Imamverdiev ◽  
T A Talibov ◽  
I F Makhmudov

Aim. To determine the status and to increase the effectiveness of open surgical treatment of bilateral staghorn nephrolithiasis. Methods. We studied the results of surgical treatment of 250 patients who underwent open surgery for severe forms of bilateral staghorn nephrolithiasis. The patients were divided into four groups according to the features of changes in both kidneys and ureters - group 1 included 125 (50.0%) patients with bilateral staghorn nephrolithiasis, group 2 - 35 (14.0%) patients with staghorn nephrolithiasis of solitary or the only functioning kidney, 70 (28.0%) patients with unilateral staghorn nephrolithiasis and solitary or multiple kidney or ureter stones on the other side were included into group 3, and group 4 inlcuded 20 (8.0%) patients with unilateral staghorn nephrolithiasis and nonobstructive hydronephrosis and other diseases on the other side. The age of patients ranged from 7 to 76 years old, ranging among children from 7 to 18 years (average age 12.1±0.4 years) and among adults from 19 to 76 years (average age 46.4±0.6 years). Among patients, 121 (48.4%) were males and 129 (51.6%) were females. Results. Surgical tactics and the results of performed surgeries in certain groups were studied. Overall, 127 (50.8±3.8%) of 250 patients underwent surgery on the right kidney, and 123 (49.2±3.2%) - on the left kidney. To achieve minimal blood loss during the surgery, in 20% of cases renal artery was clamped. To protect kidneys from ischemia, 3 mg/kg of furosemide, 0.2 mg/kg of verapamil and 1 mg/kg of methylethylpiridinol were used before and after clamping of the renal artery. Open surgical treatment of 250 patients with bilateral staghorn nephrolithiasis was successful in 246 (98.4±0.8%) patients. In case of residual stones, extracorporeal or ureterorenoscopic shock wave lithotripsy was performed. Conclusion. Despite the wide application of modern endoscopic methods of therapy in the treatment of this group of patients, in complex forms of staghorn nephrolithiasis open surgery is more effective.


1918 ◽  
Vol 27 (4) ◽  
pp. 449-458 ◽  
Author(s):  
Kingo Goto

1. The present work was undertaken to study the metabolism in the dog after a ureter-intestinal transplantation. Four dogs, Nos. I, 2, 5, and 7, were originally operated upon. Two, Nos. 2 and 7, showed kidney infection; the other two were not infected, and in these the metabolism was studied; one of the latter (No. 1) showed marked hydronephrosis and hydroureter. 2. Both after the transplantation of the right ureter into the intestine and the ligation of the right ureter, there is generally a moderately increased output of nitrogen in the urine and, in the former instance especially, a retention of nitrogen in the blood, but no change in carbon dioxide content in the blood. The significance of this is probably an increased tissue catabolism, the cause of which is doubtful without further work. 3. After removal of the left kidney subsequent to transplantation of the right ureter into the duodenum, renal insufficiency and resulting retention developed. The non-protein and urea nitrogen in the blood steadily increased and the carbon dioxide content of the blood diminished to the level characteristic of a moderate acidosis. No ketones were found in the blood The dogs died 5 to 10 days after the nephrectomy under conditions characteristic of suspended renal activity—deep respiration, unconsciousness, and sopor.


2018 ◽  
Vol 64 (4) ◽  
pp. 533-538
Author(s):  
Oleg Bogomolov ◽  
Mikhail Shkolnik ◽  
Andrey Stanzhevskiy ◽  
Anna Ivanova ◽  
A. Dolbov

Splenosis is the autotransplantation of splenic tissue that occurs in patients over a period of time as the outcome of a traumatic rupture of the spleen in an anamnesis. In most cases, splenic foci occur in the abdomen and small pelvis due to dissemination of fragments of the spleen tissue during it's rupture, however these heterotopic foci can occur almost anywhere in the body, and their diffuse nature may cause suspicion of metastatic cancer. Our case of abdomen and retroperitoneal space splenosis in combination with right kidney cancer, is a rare observation.


2012 ◽  
Vol 16 (6) ◽  
pp. 615-623 ◽  
Author(s):  
Armen R. Deukmedjian ◽  
Tien V. Le ◽  
Elias Dakwar ◽  
Carlos R. Martinez ◽  
Juan S. Uribe

Object The minimally invasive lateral interbody fusion of the lumbar spine through a retroperitoneal transpsoas approach has become increasingly used. Although preoperative imaging is performed supine, the procedure is performed with the patient in the lateral decubitus position. The authors measured the changes in location of the psoas muscle, aorta, inferior vena cava (IVC), iliac vessels, and kidneys with regard to the fixed lumbar spine when moving from a supine to a lateral decubitus position. Methods Unenhanced lumbar MRI scans were performed using a 3T magnet in 10 skeletally mature volunteers in the supine, left lateral decubitus (LLD), and right lateral decubitus (RLD) positions. Positional changes in the aorta, IVC, iliac vessels, and kidneys were then analyzed at all lumbar levels when moving from supine to RLD and supine to LLD. Values are presented as group means. Results When the position was changed from supine to RLD, both the aorta and the IVC moved up to 6 mm to the right, with increased movement caudally at L3–4. The aorta was displaced 2 mm anteriorly at L1–2, and the IVC moved 3 mm anteriorly at L1–2 and L2–3 and 1 mm posteriorly at L3–4. The left kidney moved 22 mm anteriorly and 15 mm caudally, while the right kidney moved 9 mm rostrally. When the position was changed from supine to LLD, the aorta moved 1.5 mm to the left at all levels, with very minimal anterior/posterior displacement. The IVC moved up to 10 mm to the left and 12 mm anteriorly, with increased movement rostrally at L1–2. The left kidney moved 3 mm anteriorly and 1 mm rostrally, while the right kidney moved 20 mm anteriorly and 5 mm caudally. The bifurcation of the aorta was an average of 18 mm above the L4–5 disc space, while the convergence of the iliac veins to form the IVC was at the level of the disc space. The iliopsoas did not move in any quantifiable direction when the position was changed from supine to lateral; its shape, however, may change to become more flat or rounded. When the position was changed from supine to RLD, the right iliac vein moved posteriorly an average of 1.5 mm behind the anterior vertebral body (VB) line (a horizontal line drawn on an axial image at the anterior VB), while the other vessels stayed predominantly anterior to the disc space. When the position was changed from supine to LLD, the right iliac vein moved to a position 1.4 mm anterior to the anterior VB line. There was negligible movement of the other vessels in this position. Conclusions The authors showed that the aorta, IVC, and kidneys moved a significant distance away from the surgical corridor with changes in position. At the L4–5 level, a left-sided approach may be riskier because the right common iliac vein trends posteriorly and into the surgical corridor, whereas in a right-sided approach it trends anteriorly.


2019 ◽  
Vol 47 ◽  
Author(s):  
Fábio Dumit Pizzinatto ◽  
Nathália Freschi ◽  
Dábila Araújo Sônego ◽  
Matias Bassinello Stocco ◽  
Nathalie Moro Bassil Dower ◽  
...  

Background: Dioctophimosis is a parasitic disease caused by Dioctophyma renale, more commonly known as "giant Kidney worm," and can be found in other organs or free in the abdominal cavity, which is related to the patient's eating habits. Most of the animals affected are asymptomatic. The diagnosis is made through ultrasonography, finding eggs of the parasite in the urine, or necropsy. The treatment of choice is nephrectomy of the affected kidney. We aimed to report the accidental diagnosis of parasitism by D. renale in an 8-year-old dog, which was surgically treated by nephrectomy of the right kidney after evident destruction of the renal parenchyma on ultrasonography.Case: An 8-year-old Boxer female dog underwent a physical examination and showed a mass in the region of the left caudal thoracic breast, bilateral alopecia on flanks, and purulent ocular secretions. Laboratory tests of complete blood count (CBC) and serum biochemical profile, X-ray examination, and ultrasonography were requested. Anemia was observed on the erythrogram, and enzymes (creatinine, urea, alanine aminotransferase [ALT], and albumin) were within normal limits. There were no abnormalities on X-ray examination, and abdominal ultrasonography showed slight splenomegaly, enlarged left kidney, reduced corticomedullary region, measuring approximately 7.63 cm longitudinally. In the right kidney, loss of the renal parenchyma, measuring approximately 5.49 cm in diameter and the presence of a cylindrical and rounded structure, typical of D. renale infection. After this, a urinalysis was suggested, which revealed the presence of the helminthic eggs, confirming the diagnosis. The owner was informed about the need for nephrectomy of the affected kidney as treatment. The kidney showed destruction of the renal parenchyma. A single parasite was removed, measuring approximately 46 cm in length. The patient was successfully treated and was hospitalized for 4 days for observation and evaluation of function of the contralateral kidney.Discussion: The parasitic infection of the animal was due to the ingestion of fish contaminated by the aquatic anelid Lumbriculus variegatus, and the reported patient had access to home-cooked food and ingested water near the farm. D. renale is the largest nematode capable of parasitizing the kidney, reaching up to 100 cm in length, and was 46 cm long in the present case. Usually, when there is unilateral involvement, the vast majority of parasitized animals do not present clinical signs or show nonspecific signs such as hematuria and apathy, or as observed in the present case, the patient is asymptomatic. The diagnosis often occurs through ultrasonography and urine tests, which are considered essential to diagnose the parasite, but the diagnosis is often made on necropsy. Due to its proximity to the duodenum, the parasite is usually found in the right kidney, and it may be found in other organs as well. In the present case, the parasite was found in the right kidney of the patient. Usually, hypertrophy of the contralateral kidney (7.86 cm in this case) is observed on ultrasonography, which is a compensatory mechanism for the lack of normal function of the affected kidney of the affected kidney. The case occurred in the state of Mato Grosso, where there are no records of parasitism by D. renale in domestic dogs, compared with other states. Since the parasite usually affects the kidney, the treatment of choice is nephrectomy, especially if the other kidney can compensate for the absence of the other kidney, a technique that proved to be effective with excellent prognosis in the patient described.


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