scholarly journals URINARY TRACT INFECTIONS IN POST OPERATIVE PATIENTS: PREVALENCE RATE, BACTERIAL PROFILE, ANTIBIOTIC SENSITIVITY AND SPECIFIC RISK FACTORS

Author(s):  
Abdulrahman Y. Al-Haifi ◽  
Abdul Salam Mohamed Al Makdad ◽  
Mohammed Kassim Salah ◽  
Hassan A. Al-Shamahy

Background and objective: Urinary tract infections (UTIs) are the most common minor complication after operations, mostly due to bladder catheterization that used routinely during operations. This investigation seeks to determine prevalence rate, bacterial features, antibiotic sensitivity and risk factors for urinary tract infection in postoperative patients in tertiary hospitals in Sana’a, Yemen. Methods: This prospective analysis included 390 patients undergoing surgery between 2017 and 2018 at Al-Thawra Hospital. The study includes 258 male and 132 female between the ages 5 to 80 years. Clinical and demographic data and factors affecting UTIs were collected in the standard questionnaire, and the sample was obtained after catheter removal; or, in patients with a clinical indication of continuous catheterization, a sample was obtained after the replacement of a new catheter. The samples were cultured, examined for significant possible bacterial pathogens, isolated and identified by standard laboratory techniques, and microbial sensitivity testing was carried out by disc diffusion method. The operative characteristics associated with postoperative UTI were also analysis. Results: Postoperative UTI (POUTI) occurred in 144/390 (37%), and the predominant post-operative uropathogen was Escherichia coli (34%), followed by Pseudomonas aeruginosa 1(27%) and Staphylococcus coagulase negative (16.7%). In Gram-negative bacteria, high resistance to ampicillin (95%), nalidixic acid (63%), ceftriaxone (68%) and cotrimoxazole (55%) was recorded, while high sensitivity to amikacin (98%) and ciprofloxacin. (84%), cefotaxime (87%), gentamicin (87%) and imipenem (98%). In Gram-positive bacteria, high resistance to penicillin (90%), erythromycin (85%), and amoxicillin (78%) was recorded, while high sensitivity to aztreonam (94%), augmentin (83%),   ciprofloxacin (93%), cefotaxime (86%), gentamicin (85%), Rifampicin (100%) and vancomycin (97%).  The following characteristics are independently associated with postoperative UTI: female sex (OR 2.1, 95% CI 1.3–3.2), Rubber PTFE catheter (OR 4.7, 95% CI 1.99–11.4), longer duration of catheterization >10 days (OR 4.4, 95% CI 2.3–8.3), overweight (OR 1.7, 95% CI 1.1–2.9), and emergency surgery  (OR 1.9, 95% CI 1.2–3.0). Conclusions: POUTI remains an important problem in our hospitals and what complicates the situation is that all the causative microorganisms are MDR with few treatment options; and several risk factors were independently associated with POUTI. Peer Review History: Received 14 May 2020; Revised 15 June; Accepted 1 July, Available online 15 July 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Amany Mohamed Alboghdadly Affiliation: Princess Nourah bint abdulrahman university, Riyadh E-mail: [email protected]   Name: Dr. A.A. Mgbahurike Affiliation: University of Port Harcourt, Nigeria E-mail: [email protected]   Comments of reviewer(s): Similar Articles: A SHORT REVIEW OF URINARY SYMPTOMATOLOGY- GRECO ARAB MEDICINE BIOFILM FORMATION AND ANTIBIOTIC SUSCEPTIBILITY OF UROPATHOGENS IN PATIENTS WITH CATHETER ASSOCIATED URINARY TRACT INFECTIONS IN IBB CITY -YEMEN

Author(s):  
Abdulrahman Y. Al-Haifi ◽  
Abdul Salam Mohamed Al Makdad ◽  
Mohammed Kassim Salah ◽  
Hassan A. Al-Shamahy ◽  
Wadee Abdullah Abdulwahid Al Shehari

Objectives:  Lower respiratory infections (LRTIs) are the leading reason of death infectious diseases in the world and the fifth leading cause of death in general. The study aimed to identify the general characteristics of LRTI, the causative bacteria and the results of sensitivity to antibiotics. Subjects and methods:  A multicentre prospective study was performed at 3 University hospitals. The study included 555 clinical diagnostic cases as LRTI cases, 328 male and 227 female, aged 3 to 69 years. Clinical and demographic data were collected in the standard questionnaire, and samples included sputum or bronchial lavage (BAL) staining and culture. Samples were cultured in 3 different bacterial media, blood agar and LJ slope, chocolate agar with Co2; cultures were then examined for possible bacterial pathogens of LRTI. Possible bacterial pathogens were isolated and identified by standard laboratory techniques, and microbial sensitivity testing was carried out by disc diffusion method. Results:  LRTI was recorded among all age groups and with less frequency in children less than 16 years of age. A large number of LRTI (36.2%) was not diagnosed, most in CAP (52.4%), followed by HAP (33.9%) while unidentified cases were lower in AECOPD (22.8%). CAP isolates are K. pneumoniae (26.2%), S. pyogens (12.3%), and S. pneumoniae (9%); in HAP are MSSA (24%), E. Coli (12.9%), MRAS (11.1%), K. pneumoniae (10.5%) and P. aeruginosa (7%); and in AECOPD are M. catarrhalis (47.2%), K. pneumoniae (17.2%), H. influnzae (10.7%) and P. aeruginosa (2%). In Gram-positive bacteria, high resistance to ampicillin/sulbactam (100%) and amoxicillin/clavulanate (100%) was recorded, while moderate resistance to amikacin, vancomycin, cefepime and moxifloxacin was recorded. In Gram-negative bacteria, a high resistance to 3rd g Cephalosporin’s  (68.5%) was recorded, while a moderate sensitivity to the other antibiotics tested was recorded. Conclusion:  There is a high rate of undiagnosed LRTI in Yemen and this highlights the need for health authorities to develop strategies to diagnose most of the causes of LRTI, including Mycoplasma, Chlamydia, and viral causes. No antibiotics are completely effective in treating LRTI in our area and antibiotic sensitivity should be performed in all cases. Peer Review History: Received 22 April 2019; Revised 4 May; Accepted 9 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Michael Otakhor Erhunmwunse Affiliation: St. Philomena Catholic Hospital, Nigeria E-mail: [email protected]   Name: Dr. Amany Mohamed Alboghdadly Affiliation: Princess Nourah bint abdulrahman university, Riyadh E-mail: [email protected] Comments of reviewer(s): Similar Articles: BIOFILM FORMATION AND ANTIBIOTIC SUSCEPTIBILITY OF UROPATHOGENS IN PATIENTS WITH CATHETER ASSOCIATED URINARY TRACT INFECTIONS IN IBB CITY -YEMEN PREVALENCE, ANTIMICROBIAL SUSCEPTIBILITY PATTERN AND RISK FACTORS OF MRSA ISOLATED FROM CLINICAL SPECIMENS AMONG MILITARY PATIENTS AT 48 MEDICAL COMPOUND IN SANA'A CITY-YEMEN


Author(s):  
Abdulrahman A. Ishak ◽  
Abdulrahman M Alhadi ◽  
Khaled Abdulkareem A Al-Moyed ◽  
Hassan A. Al-Shamahy

Background and objective: Urinary tract infections (UTIs) are the neglected infection in children from the side of study its clinical symptoms, causative organisms and their antibiotic sensitivity. This investigation searches for determine clinical symptoms frequency, prevalence rate, bacterial features, and  antibiotic sensitivity of bacterial urinary tract infection in children attending private children’s health center in Sana’a city. Methods: In a prospective study carried out over a 24-month period, 1925 samples from children patients suspected of having a UTI were investigated, of which 175 were culture-positive. Clinical and demographic data were collected. Isolated bacteria were identified by standard tests, and antibiotic susceptibility was performed by the disk diffusion method. Results: Fever was the most frequent symptom that occurred (88%) while other UTI symptoms were less frequent than that reported in adult patients for UTI. The most common etiological agent was Escherichia coli (89.7%), followed Staphylococcus aureus (3.4%), Klebsiella spp (2.9%), Proteus spp (2.3%), and beta haemolytic streptococci (1.7%).  Results of antimicrobial resistant for E. coli, as the most prevalent cause of UTI, to commonly used antibiotics are ranged from less than 3% for  levofloxacin, gentamicin,  amikacin and cefoxitin to more than 75% for  tetracycline, nalidixic acid,  doxycycline,  co-trimoxazol and amoxicillin . Conclusions: The results show the most common  symptom of UTI are fever and lack of more obvious symptoms of UTI in adult patients. The antimicrobial resistance patterns of the causes of UTI are highly changeable and constant surveillance of trends in resistance patterns of uropathogens among children  is essential.                   Peer Review History: Received: 11 July 2021; Revised: 13 August; Accepted: 5 September, Available online: 15 September 2021 Academic Editor:  Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Dr. Nuray Arı, Ankara University, Turkiye, [email protected] Dr. Salfarina Ramli,  Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor, Malaysia. [email protected]   Dr. Wadhah Hassan Ali Edrees, Hajja University, Yemen, [email protected] Dr. Asia Selman Abdullah, University of Basrah, Iraq, [email protected] Similar Articles: URINARY TRACT INFECTIONS IN POST OPERATIVE PATIENTS: PREVALENCE RATE, BACTERIAL PROFILE, ANTIBIOTIC SENSITIVITY AND SPECIFIC RISK FACTORS  BIOFILM FORMATION AND ANTIBIOTIC SUSCEPTIBILITY OF UROPATHOGENS IN PATIENTS WITH CATHETER ASSOCIATED URINARY TRACT INFECTIONS IN IBB CITY -YEMEN


2021 ◽  
Vol 22 (8) ◽  
Author(s):  
Suhartono Suhartono ◽  
Wilda Mahdani ◽  
Zinatul Hayati ◽  
NURHALIMAH NURHALIMAH

Abstract. Suhartono S, Mahdani W, Hayati Z, Nurhalimah N. 2021. Species distribution of Enterobacteriaceae and non-Enterobacteriaceae responsible for urinary tract infections at the Zainoel Abidin Hospital in Banda Aceh, Indonesia. Biodiversitas 22: 3313-3318. Urinary tract infection (UTI) is an infection that occurs along the urinary tract caused by pathogenic bacteria. Enterobacteriaceae and non-Enterobacteriaceae are generally normal flora originating from the large intestine and vaginal mucosa. This study aimed to assess the distribution of Enterobacteriaceae and non -Enterobacteriaceae pathogens that cause UTI based on species diversity, patient age, gender, and hospital units, and to evaluate their antibiotic sensitivity to uropathogens in ZAH. In total, there were 284 isolates classified as UTI pathogens with 178 Enterobacteriaceae isolates dominated by Escherichia coli and 107 non- Enterobacteriaceae isolates. Non- Enterobacteriaceae consisted of 77 isolates of Gram-positive dominated by Enterococcus faecalis and Enterococcus facium, and 29 isolates of Gram-negative dominated by Acinetobacter baumannii. The highest UTI ratio was found in the elderly (56-65 years), namely 66.2% Enterobacteriaceae and 33.8% non-Enterobacteriaceae isolates. Based on gender, females were infected with Enterobacteriaceae (66.86%) and non-Enterobacteriaceae (37.41%). Most of UTI patients in the internal medicine unit were infected with Enterobacteriaceae (55.36%) and non-Enterobacteriaceae (44.64%). Amikacin, meropenem, and levofloxacin were antibiotics that had high sensitivity against Enterobacterial and non-Enterobacterial uropathogens. The emergence of Gram-positive uropathogens need to be concerned as these groups start emerging. It is also important to monitor regularly the antibiotic susceptibility of bacterial UTI pathogens to ensure the efficacy of current UTI treatments and minimize the UTI incidence in nosocomial settings.


Infection ◽  
2009 ◽  
Vol 38 (1) ◽  
pp. 41-46 ◽  
Author(s):  
K. Cohen-Nahum ◽  
L. Saidel-Odes ◽  
K. Riesenberg ◽  
F. Schlaeffer ◽  
A. Borer

Menopause ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Amanda Ingram ◽  
Tasha Posid ◽  
Aroh Pandit ◽  
Justin Rose ◽  
Sabrina Amin ◽  
...  

2010 ◽  
Vol 17 (3) ◽  
pp. 103
Author(s):  
L. CERSOSIMO ◽  
F. CATANZARO ◽  
E. IMPARATO ◽  
M. MESCHIA ◽  
T. MAZZEI ◽  
...  

Non complicated acute urinary tract infections (UTI) are among the most common bacterial diseases in the human species. More than 150 million UTIs (non complicated/complicated) are, in fact, annually diagnosed and treated worlwide (Sobel Kaye, 1990; Stamm and Hooton, 1993; Stamm, 1998; Stamm and Norrby, 2001; Foxman, 2002). UTI include cystitis and pyelonephritis (the latter is not discussed in this paper) that occur in individuals without morphological-functional alterations of the excretory tract. This disease is more common in female and/or in menopause patients. 25-50% of the individuals in this population, aged between 20 and 40 years, can be affected by UTI at least once in a lifetime and can be prone to more or less frequent relapses. (Johnson, 1998; Stamm, 2001). Male subjects are less frequently affected by UTI, but when affected, they experience more serious episodes often representing a warning signal of anatomical alterations of the urinary apparatus or the presence of risk factors.......


2014 ◽  
Vol 27 (3) ◽  
pp. 364 ◽  
Author(s):  
Ana Bispo ◽  
Milene Fernandes ◽  
Cristina Toscano ◽  
Teresa Marques ◽  
Domingos Machado ◽  
...  

<strong>Introduction:</strong> Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients.<br /><strong>Material and Methods:</strong> This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections.<br /><strong>Results:</strong> A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p &lt; 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p &lt; 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the<br />most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions.<br /><strong>Discussion:</strong> Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated.<br /><strong>Conclusion:</strong> Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions.<br /><strong>Keywords:</strong> Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.


2013 ◽  
Vol 17 (1) ◽  
pp. 7-12
Author(s):  
Özlem Boybeyi ◽  
İbrahim Karnak ◽  
Arbay Özden Ciftci ◽  
Feridun Cahit Tanyel ◽  
Mehmet Emin Şenocak

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