Post-infectious bronchiolitis obliterans in children

2011 ◽  
Vol 0 (0) ◽  
Author(s):  
Natália da Silva Champs ◽  
Laura M. L. B. F. Lasmar ◽  
Paulo A. M. Camargos ◽  
Christophe Marguet ◽  
Gilberto Bueno Fischer ◽  
...  
Keyword(s):  
Bronchiolitis Obliterans ◽  
Post Infectious

scholarly journals Phenotypical Characterization of Airway Morphology in Post-Infectious vs Post-Lung Transplantation Bronchiolitis Obliterans

2021 ◽  
Vol 40 (4) ◽  
pp. S36
Author(s):  
A. Vanstapel ◽  
B. Weynand ◽  
A. De Zutter ◽  
A. Dubbeldam ◽  
L. De Sadeleer ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Bronchiolitis Obliterans ◽  
Airway Morphology ◽  
Post Infectious

Post-infectious bronchiolitis obliterans

2004 ◽  
Vol 37 (S26) ◽  
pp. 64-65 ◽  
Author(s):  
Marcus H. Jones ◽  
Paulo M�rcio Pitrez ◽  
Renato T. Stein
Keyword(s):  
Bronchiolitis Obliterans ◽  
Post Infectious

Clinical Characteristics of Post-Infectious Bronchiolitis Obliterans

2011 ◽  
Vol 21 (3) ◽  
pp. 156 ◽  
Author(s):  
Jin Young Shin ◽  
Mi Ju ◽  
Kye Hyang Lee ◽  
Hye Jin Park ◽  
Kyung Hoon Lee ◽  
...  
Keyword(s):  
Bronchiolitis Obliterans ◽  
Clinical Characteristics ◽  
Post Infectious

scholarly journals Post-infectious Bronchiolitis Obliterans: HRCT, DECT, Pulmonary Scintigraphy Images, and Clinical Follow-up in Eight Children

2020 ◽  
Vol 8 ◽  
Author(s):  
I-Chen Chen ◽  
Jui-Sheng Hsu ◽  
Yu-Wen Chen ◽  
Yi-Ching Liu ◽  
Yen-Hsien Wu ◽  
...  
Keyword(s):  
Bronchiolitis Obliterans ◽  
Study Data ◽  
University Hospital ◽  
Pulmonary Scintigraphy ◽  
Chest X Ray ◽  
Clinical Profiles ◽  
Medical University ◽  
Post Infectious ◽  
Hrct Finding

Background: Bronchiolitis obliterans (BO), first mentioned in 1901, is a severe and rare chronic lung disease in children. BO has various etiologies and the most common in children is post-infectious BO (PIBO). High resolution CT (HRCT) is an often-used image tool for the diagnosis of BO, and pulmonary scintigraphy is an alternative tool that can functionally evaluate BO. Recently, dual-energy computed tomography (DECT) have also been applied to BO for its accuracy and safety. Here we described the characteristics of HRCT, pulmonary scintigraphy, DECT, and the clinical profiles of patients with PIBO.Methods: This is a retrospective and descriptive study. Data were collected from patients diagnosed with PIBO from 2014 to 2019 in the Pediatric Cardiopulmonary Outpatient Clinics of Kaohsiung Medical University Hospital. The diagnosis was based on clinical, chest X-ray, and HRCT findings. Clinical profile, radiological characteristics, and images of pulmonary scintigraphy were documented.Results: Eight children (4 boys and 4 girls) were diagnosed with PIBO at a mean age of 25.8 months (range 15 to 41 months). Two of our patients developed pulmonary hypertension. The most common HRCT finding is mosaic pattern, where match ventilation/perfusion (V/Q) defects is a general feature in pulmonary scintigraphy. DECT pulmonary blood vasculature images revealed various degrees of decreased perfusion and is compatible with the decreased perfusion on pulmonary scintigraphy.Conclusion: The therapeutic strategy of PIBO is still lacking of standardization. HRCT and V/Q scans are important image tools in diagnosis and follow-up of BO. DECT may be used in BO patients as it has no additional radiation exposure and add value on functional information of HRCT.

scholarly journals Complication of post-infectious bronchiolitis obliterans (Swyer-James syndrome)

2015 ◽  
Vol 61 (5) ◽  
pp. 404-406 ◽  
Author(s):  
Gabriel de Deus Vieira ◽  
Alessandra Yukari Yamagishi ◽  
Natália Nogueira Vieira ◽  
Rebeka Mayara Miranda Dias Fogaça ◽  
Thaianne da Cunha Alves ◽  
...  
Keyword(s):  
Bronchiolitis Obliterans ◽  
Signs And Symptoms ◽  
Wall Thickening ◽  
Radiological Findings ◽  
Air Trapping ◽  
Bronchial Wall ◽  
Pulmonary Lesions ◽  
Post Infectious ◽  
Radiological Examinations

Summary Swyer-James syndrome is a complication of post-infectious bronchiolitis obliterans that causes inflammation and fibrosis of the bronchial walls. There are two types: asymptomatic, with most cases diagnosed in adults during routine radiological examinations; and symptomatic, most commonly found in children. Here, we report the case of a 6-year-old child with recurrent dyspnea since the age of 3, who showed signs and symptoms of bronchiolitis obliterans and radiological signs of bronchial wall thickening and air trapping. The clinical and radiological findings led to the diagnosis of Swyer-James syndrome. Treatment of this syndrome is intended to reduce the pulmonary lesions and improve the patient's quality of life.

scholarly journals Clinical and follow-up study of bronchiolitis obliterans in pediatric patients in China

2017 ◽  
Vol 15 (3) ◽  
pp. 152-159 ◽  
Author(s):  
Li Huang ◽  
Yaping Xie ◽  
Huifeng Fan ◽  
Gen Lu ◽  
Jialu Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bronchiolitis Obliterans ◽  
Pediatric Patients ◽  
Medical Center ◽  
Pulmonary Function Tests ◽  
Age At Onset ◽  
Airflow Obstruction ◽  
High Resolution Computed Tomography ◽  
Significant Difference ◽  
Post Infectious

Bronchiolitis obliterans (BO) is in general a rare and life-threatening form of non-reversible obstructive lung disease in which the bronchioles are compressed and narrowed by fibrosis and/or inflammation. The purpose of this study was to evaluate the clinical features of BO in pediatric patients and explore its risk factors. The medical records of 35 pediatric patients with BO at Guangzhou Women and Children’s Medical Center were evaluated. The age at onset of symptoms was 2–42 months (mean 13.3 ± 8.9 months), with age at diagnosis of 5 months–4 years (mean 17.8 ± 9.0 months). High-resolution computed tomography findings included mosaic pattern (100%), atelectasis (37.1%), air trapping (31.4%), and bronchiectasis (20.0%). Three patients received lung biopsies and mainly exhibited an inflammatory process surrounding the lumen of bronchioles. BO predominantly resulted from post-infectious causes (91.4%) which were primarily caused by adenovirus (50%), followed by Mycoplasma pneumoniae (46.7%) and influenza (20%). Pulmonary function tests (PFTs) showed severe and fixed airflow obstruction, decreased compliance, and increased resistance. No significant difference was found between before and after steroid treatment ( P > 0.05). Two patients died owing to severe pulmonary complications, one of whom had inherent immunodeficiency. Our study suggests that the occurrence of BO, especially post-infectious BO, in China is relatively high and might result from primary immunodeficiency diseases in severe cases. Recurrent aspiration pneumonia caused by congenital dysplasia of the larynx and vaccination not on schedule might be potential risk factors for persistent and recurrent BO.

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