scholarly journals Synergistic Effects of Helicobacter pylori Outer Inflammatory Protein A (oipA) and cag Pathogenicity Island (cag PAI) on Interleukin-1β and Interleukin-8 Gene Expression Levels in Gastric Tissues of Thai Gastroduodenal Patients

2018 ◽  
Vol 12 (2) ◽  
pp. 459-466
Author(s):  
Wongwarut Boonyanugomol ◽  
Kamolchanok Rukseree ◽  
Prasit Palittapongarnpim ◽  
Worrarat Kongkasem ◽  
Seung-Chul Baik
2018 ◽  
Vol 59 ◽  
pp. 167-171 ◽  
Author(s):  
Rumyana Markovska ◽  
Lyudmila Boyanova ◽  
Daniel Yordanov ◽  
Petya Stankova ◽  
Galina Gergova ◽  
...  

Cytokine ◽  
2008 ◽  
Vol 41 (3) ◽  
pp. 302-306 ◽  
Author(s):  
Toshiyuki Yasui ◽  
Hirokazu Uemura ◽  
Masayo Yamada ◽  
Toshiya Matsuzaki ◽  
Naoko Tsuchiya ◽  
...  

2003 ◽  
Vol 71 (4) ◽  
pp. 2153-2162 ◽  
Author(s):  
Toshiki Nishi ◽  
Kazuichi Okazaki ◽  
Kimio Kawasaki ◽  
Toshiro Fukui ◽  
Hiroyuki Tamaki ◽  
...  

ABSTRACT We previously described an animal model of Helicobacter pylori-induced follicular gastritis in neonatally thymectomized (nTx) mice. However, it is still not clear whether antigen-presenting dendritic cells (DCs) in the stomach have a role in the development of secondary follicles in H. pylori-infected nTx mice. We investigated the distribution of DC subsets using this model and examined their roles. To identify lymphoid and myeloid DCs, sections were stained with anti-CD11c (pan-DC marker) in combination with anti-CD8α (lymphoid DC marker) or anti-CD11b (myeloid DC marker) and were examined with a confocal microscope. Expression of macrophage inflammatory protein 3α (MIP-3α), which chemoattracts immature DCs, was analyzed by real-time PCR and immunohistochemistry. Follicular dendritic cells (FDCs) were stained with anti-SKY28 antibodies. In noninfected nTx mice, a few myeloid and lymphoid DCs were observed in the bottom portion of the lamina propria, whereas in H. pylori-infected nTx mice, there was an increased influx of myeloid DCs throughout the lamina propria. FDC staining was also observed in the stomachs of members of the infected group. MIP-3α gene expression was upregulated in the infected nTx group, and the immunohistochemistry analysis revealed MIP-3α-positive epithelial cells. These data suggest that H. pylori infection upregulates MIP-3α gene expression in gastric epithelial cells and induces an influx of myeloid DCs in the lamina propria of the gastric mucosa in nTx mice. Myeloid DCs and FDCs might contribute to the development of gastric secondary lymphoid follicles in H. pylori-infected nTx mice.


2005 ◽  
Vol 11 (5) ◽  
pp. 447-454 ◽  
Author(s):  
Karen M Lammers ◽  
Athanasios Vergopoulos ◽  
Nina Babel ◽  
Paolo Gionchetti ◽  
Fernando Rizzello ◽  
...  

2003 ◽  
Vol 47 (6) ◽  
pp. 1759-1759 ◽  
Author(s):  
Wolfgang Fischer ◽  
Jürgen Püls ◽  
Renate Buhrdorf ◽  
Bettina Gebert ◽  
Stefan Odenbreit ◽  
...  

1996 ◽  
Vol 116 (2) ◽  
pp. 302-306 ◽  
Author(s):  
Chong Sun Kim ◽  
Chul Hee Lee ◽  
Jong Woo Chung ◽  
Chun Dong Kim

2002 ◽  
Vol 42 (5) ◽  
pp. 1337-1348 ◽  
Author(s):  
Wolfgang Fischer ◽  
Jürgen Püls ◽  
Renate Buhrdorf ◽  
Bettina Gebert ◽  
Stefan Odenbreit ◽  
...  

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