scholarly journals Optimisation of BMP-2 dosage for the osseointegration of porous titanium implants in an ovine model

2016 ◽  
Vol 32 ◽  
pp. 241-256 ◽  
Author(s):  
EB Hunziker ◽  
◽  
J Jovanovic ◽  
A Horner ◽  
MJB Keel ◽  
...  
2015 ◽  
Vol 30 (3) ◽  
pp. 484-488 ◽  
Author(s):  
Nicky Bertollo ◽  
Enrico Sandrini ◽  
Paolo Dalla Pria ◽  
William R. Walsh

2011 ◽  
Vol 6 (1) ◽  
pp. 56 ◽  
Author(s):  
Dong Chen ◽  
Nicky Bertollo ◽  
Abe Lau ◽  
Naoya Taki ◽  
Tomofumi Nishino ◽  
...  

2017 ◽  
Vol 58 ◽  
pp. 550-560 ◽  
Author(s):  
Anish Shivaram ◽  
Susmita Bose ◽  
Amit Bandyopadhyay

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 461
Author(s):  
Paula Navarro ◽  
Alberto Olmo ◽  
Mercè Giner ◽  
Marleny Rodríguez-Albelo ◽  
Ángel Rodríguez ◽  
...  

The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. The present work studies a non-invasive alternative of electrical impedance spectroscopy for the characterization of the macroporosity inherent to the manufacturing process and the effect of the surface treatment with femtosecond laser of titanium discs. Osteoblasts cell culture growths on the titanium surfaces of the laser-treated discs were also studied with this method. The measurements obtained showed that the femtosecond laser treatment of the samples and cell culture produced a significant increase (around 50%) in the absolute value of the electrical impedance module, which could be characterized in a wide range of frequencies (being more relevant at 500 MHz). Results have revealed the potential of this measurement technique, in terms of advantages, in comparison to tiresome and expensive techniques, allowing semi-quantitatively relating impedance measurements to porosity content, as well as detecting the effect of surface modification, generated by laser treatment and cell culture.


2015 ◽  
Vol 29 ◽  
pp. 141-154 ◽  
Author(s):  
J van der Stok ◽  
◽  
MKE Koolen ◽  
MPM de Maat ◽  
S Amin Yavari ◽  
...  

2018 ◽  
Vol 6 (15) ◽  
pp. 2274-2288 ◽  
Author(s):  
Xiao-Fan Hu ◽  
Ya-Fei Feng ◽  
Geng Xiang ◽  
Wei Lei ◽  
Lin Wang

PLGA-coating on 3D-printed porous titanium implants promoted the angiogenesis and osteointegration at bone-implant interface in diabetes by releasing lactic acid.


Bioceramics ◽  
1991 ◽  
pp. 335-342
Author(s):  
A. Moroni ◽  
V. Pezzuto ◽  
G. Rollo ◽  
F. Gottsauner-Wolf ◽  
V. Caja ◽  
...  

2020 ◽  
Vol 383 ◽  
pp. 125192 ◽  
Author(s):  
Igor V. Smirnov ◽  
Roman V. Deev ◽  
Ilya I. Bozo ◽  
Alexander Yu. Fedotov ◽  
Alex N. Gurin ◽  
...  

Metals ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 569 ◽  
Author(s):  
Khaja Moiduddin ◽  
Syed Hammad Mian ◽  
Hisham Alkhalefah ◽  
Usama Umer

Segmental mandibular reconstruction has been a challenge for medical practitioners, despite significant advances in medical technology. There is a recent trend in relation to customized implants, made up of porous structures. These lightweight prosthesis scaffolds present a new direction in the evolution of mandibular restoration. Indeed, the design and properties of porous implants for mandibular reconstruction should be able to recover the anatomy and contour of the missing region as well as restore the functions, including mastication, swallowing, etc. In this work, two different designs for customized prosthesis scaffold have been assessed for mandibular continuity. These designs have been evaluated for functional and aesthetic aspects along with effective osseointegration. The two designs classified as top and bottom porous plate and inner porous plate were designed and realized through the integration of imaging technology (computer tomography), processing software and additive manufacturing (Electron Beam Melting). In addition, the proposed designs for prosthesis scaffolds were analyzed for their biomechanical properties, structural integrity, fitting accuracy and heaviness. The simulation of biomechanical activity revealed that the scaffold with top and bottom porous plate design inherited lower Von Mises stress (214.77 MPa) as compared to scaffold design with inner porous plate design (360.22 MPa). Moreover, the top and bottom porous plate design resulted in a better fit with an average deviation of 0.8274 mm and its structure was more efficiently interconnected through the network of channels without any cracks or powder material. Verily, this study has demonstrated the feasibility and effectiveness of the customized porous titanium implants in mandibular reconstruction. Notice that the design and formation of the porous implant play a crucial role in restoring the desired mandibular performance.


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