scholarly journals Digital Design, Analysis and 3D Printing of Prosthesis Scaffolds for Mandibular Reconstruction

Metals ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 569 ◽  
Author(s):  
Khaja Moiduddin ◽  
Syed Hammad Mian ◽  
Hisham Alkhalefah ◽  
Usama Umer
Keyword(s):  
Structural Integrity ◽  
Porous Plate ◽  
Biomechanical Properties ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Digital Design ◽  
Mandibular Reconstruction ◽  
Von Mises Stress ◽  
Average Deviation ◽  
Plate Design

Segmental mandibular reconstruction has been a challenge for medical practitioners, despite significant advances in medical technology. There is a recent trend in relation to customized implants, made up of porous structures. These lightweight prosthesis scaffolds present a new direction in the evolution of mandibular restoration. Indeed, the design and properties of porous implants for mandibular reconstruction should be able to recover the anatomy and contour of the missing region as well as restore the functions, including mastication, swallowing, etc. In this work, two different designs for customized prosthesis scaffold have been assessed for mandibular continuity. These designs have been evaluated for functional and aesthetic aspects along with effective osseointegration. The two designs classified as top and bottom porous plate and inner porous plate were designed and realized through the integration of imaging technology (computer tomography), processing software and additive manufacturing (Electron Beam Melting). In addition, the proposed designs for prosthesis scaffolds were analyzed for their biomechanical properties, structural integrity, fitting accuracy and heaviness. The simulation of biomechanical activity revealed that the scaffold with top and bottom porous plate design inherited lower Von Mises stress (214.77 MPa) as compared to scaffold design with inner porous plate design (360.22 MPa). Moreover, the top and bottom porous plate design resulted in a better fit with an average deviation of 0.8274 mm and its structure was more efficiently interconnected through the network of channels without any cracks or powder material. Verily, this study has demonstrated the feasibility and effectiveness of the customized porous titanium implants in mandibular reconstruction. Notice that the design and formation of the porous implant play a crucial role in restoring the desired mandibular performance.

scholarly journals Understanding long-term silver release from surface modified porous titanium implants

2017 ◽  
Vol 58 ◽  
pp. 550-560 ◽  
Author(s):  
Anish Shivaram ◽  
Susmita Bose ◽  
Amit Bandyopadhyay
Keyword(s):  
Porous Titanium ◽  
Titanium Implants ◽  
Silver Release ◽  
Surface Modified

scholarly journals Electrical Impedance of Surface Modified Porous Titanium Implants with Femtosecond Laser

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 461
Author(s):  
Paula Navarro ◽  
Alberto Olmo ◽  
Mercè Giner ◽  
Marleny Rodríguez-Albelo ◽  
Ángel Rodríguez ◽  
...  
Keyword(s):  
Cell Culture ◽  
Femtosecond Laser ◽  
Laser Treatment ◽  
Electrical Impedance ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Electrical Impedance Spectroscopy ◽  
Wide Range ◽  
Titanium Surfaces ◽  
Surface Modified

The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. The present work studies a non-invasive alternative of electrical impedance spectroscopy for the characterization of the macroporosity inherent to the manufacturing process and the effect of the surface treatment with femtosecond laser of titanium discs. Osteoblasts cell culture growths on the titanium surfaces of the laser-treated discs were also studied with this method. The measurements obtained showed that the femtosecond laser treatment of the samples and cell culture produced a significant increase (around 50%) in the absolute value of the electrical impedance module, which could be characterized in a wide range of frequencies (being more relevant at 500 MHz). Results have revealed the potential of this measurement technique, in terms of advantages, in comparison to tiresome and expensive techniques, allowing semi-quantitatively relating impedance measurements to porosity content, as well as detecting the effect of surface modification, generated by laser treatment and cell culture.

scholarly journals Mechanical Strength Study of a Cranial Implant Using Computational Tools

2022 ◽  
Vol 12 (2) ◽  
pp. 878
Author(s):  
Pedro O. Santos ◽  
Gustavo P. Carmo ◽  
Ricardo J. Alves de Sousa ◽  
Fábio A. O. Fernandes ◽  
Mariusz Ptak
Keyword(s):  
Structural Integrity ◽  
Mechanical Performance ◽  
Skull Fracture ◽  
Human Head ◽  
Element Model ◽  
Von Mises Stress ◽  
Cranial Implant ◽  
Von Mises ◽  
Two Parameters ◽  
The Brain

The human head is sometimes subjected to impact loads that lead to skull fracture or other injuries that require the removal of part of the skull, which is called craniectomy. Consequently, the removed portion is replaced using autologous bone or alloplastic material. The aim of this work is to develop a cranial implant to fulfil a defect created on the skull and then study its mechanical performance by integrating it on a human head finite element model. The material chosen for the implant was PEEK, a thermoplastic polymer that has been recently used in cranioplasty. A6 numerical model head coupled with an implant was subjected to analysis to evaluate two parameters: the number of fixation screws that enhance the performance and ensure the structural integrity of the implant, and the implant’s capacity to protect the brain compared to the integral skull. The main findings point to the fact that, among all tested configurations of screws, the model with eight screws presents better performance when considering the von Mises stress field and the displacement field on the interface between the implant and the skull. Additionally, under the specific analyzed conditions, it is observable that the model with the implant offers more efficient brain protection when compared with the model with the integral skull.

scholarly journals Full regeneration of segmental bone defects using porous titanium implants loaded with BMP-2 containing fibrin gels

2015 ◽  
Vol 29 ◽  
pp. 141-154 ◽  
Author(s):  
J van der Stok ◽  
◽  
MKE Koolen ◽  
MPM de Maat ◽  
S Amin Yavari ◽  
...  
Keyword(s):  
Bone Defects ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Fibrin Gels ◽  
Segmental Bone ◽  
Segmental Bone Defects

Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone

2018 ◽  
Vol 6 (15) ◽  
pp. 2274-2288 ◽  
Author(s):  
Xiao-Fan Hu ◽  
Ya-Fei Feng ◽  
Geng Xiang ◽  
Wei Lei ◽  
Lin Wang
Keyword(s):  
Lactic Acid ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Bone Implant ◽  
3D Printed

PLGA-coating on 3D-printed porous titanium implants promoted the angiogenesis and osteointegration at bone-implant interface in diabetes by releasing lactic acid.

Porous Titanium Implants with and without Hydroxyapatite Coating: A Biomechanical Study

Bioceramics ◽  
1991 ◽  
pp. 335-342
Author(s):  
A. Moroni ◽  
V. Pezzuto ◽  
G. Rollo ◽  
F. Gottsauner-Wolf ◽  
V. Caja ◽  
...  
Keyword(s):  
Porous Titanium ◽  
Biomechanical Study ◽  
Titanium Implants ◽  
Hydroxyapatite Coating

scholarly journals Manufacturing and Characterisation of Robot Assisted Microplasma Multilayer Coating of Titanium Implants : Biocompatible coatings for medical implants with improved density and crystallinity

2020 ◽  
Vol 64 (2) ◽  
pp. 180-191 ◽  
Author(s):  
D. Alontseva ◽  
E. Ghassemieh ◽  
S. Voinarovych ◽  
O. Kyslytsia ◽  
Y. Polovetskyi ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Structural Integrity ◽  
New Technologies ◽  
Lower Layer ◽  
Multilayer Coating ◽  
Titanium Implants ◽  
Dense Layer ◽  
Medical Implants ◽  
Robot Assisted ◽  
Tissue Integration

This study focuses on new technologies for the production of medical implants using a combination of robotics and microplasma coatings. This involves robot assisted microplasma spraying (MPS) of a multilayer surface structure on a biomedical implant. The robot motion design provides a consistent and customised plasma coating operation. Based on the analytical model results, certain spraying modes were chosen to form the optimised composition and structure of the titanium/hydroxyapatite (HA) multilayer coatings. It is desirable that the Ti coated lower layer offer a dense layer to provide the implant with suitable structural integrity and the Ti porous layer and HA top layer present biocompatible layers which are suitable for implant and tissue integration. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD) were used to analyse the structure of the coatings. The new robot assisted MPS technique resulting from this research provides a promising solution for medical implant technology.

In Vivo Imaging of Dynamic Shear Modulus of Rodent Mammary Tumors Using Ultrasound

2012 ◽  
Author(s):  
Yue Wang ◽  
Michael Insana
Keyword(s):  
In Vivo Imaging ◽  
Normal Tissue ◽  
Breast Tissue ◽  
Structural Integrity ◽  
Biomechanical Properties ◽  
Dynamic Shear Modulus ◽  
Living Tissue ◽  
Dynamic Shear

Biomechanical properties of living tissue are very important in maintaining normal tissue function, cellular and extracellular structural integrity. Therefore, the quantitative determination of biomechanical properties of breast tissue, especially in vivo, serves an important role in clinical diagnosis.

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