Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments

2012 ◽  
Vol 13 (5) ◽  
pp. 595-613 ◽  
Author(s):  
David Della-Morte ◽  
Fiorella Guadagni ◽  
Raffaele Palmirotta ◽  
Gianluca Testa ◽  
Valeria Caso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Related Risk

scholarly journals The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke

2019 ◽  
Vol 126 ◽  
pp. 13-22 ◽  
Author(s):  
Mingyue Xu ◽  
Michael M. Wang ◽  
Yanqin Gao ◽  
Richard F. Keep ◽  
Yejie Shi
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
White Matter ◽  
White Matter Injury ◽  
Age Related ◽  
Related Risk ◽  
Injury And Repair ◽  
Effect Of Age

scholarly journals Genetic polymorphisms and related risk factors of ischemic stroke in a Mongolian population in China

2017 ◽  
Vol 21 (5) ◽  
pp. 581-587 ◽  
Author(s):  
Q. Wu ◽  
H. Wu ◽  
Yu. L. Orlov ◽  
G. Gegentana ◽  
W. Huo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Genetic Polymorphisms ◽  
Related Risk

High prevalence of stroke and uncontrolled associated risk factors are major public health challenges in rural northeast China: A population-based study

2019 ◽  
Vol 15 (4) ◽  
pp. 399-411 ◽  
Author(s):  
Liying Xing ◽  
Li Jing ◽  
Yuanmeng Tian ◽  
Shiwei Liu ◽  
Min Lin ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Ischemic Stroke ◽  
Northeast China ◽  
Population Based ◽  
World Health ◽  
Current Status ◽  
Related Risk ◽  
High Prevalence ◽  
Associated Risk Factors

Background Stroke has become a major burden and public health problem in rural China. We aimed to comprehensively assess the current status of stroke burden as well as the associated risk factors in rural northeast China. Methods This population-based, cross-sectional study was conducted in 10,926 adults (response rate 85.3%) aged ≥40 years residing in rural northeast China. A multistage cluster sampling method was used to select the representative sample. The prevalent stroke cases were considered as stroke survivors on 31 August 2017. Stroke was diagnosed according to the World Health Organization’s recommendations and was classified as ischemic stroke and hemorrhagic stroke based on the results of computed tomography or magnetic resonance imaging. The status of related risk factors was also evaluated. Results Of the 10,926 participants, 731 were diagnosed with stroke (602 patients with ischemic stroke, 151 with hemorrhage stroke, and 22 with both ischemic stroke and hemorrhage stroke). The crude prevalence of overall stroke, ischemic stroke, and hemorrhage stroke was 6690.5, 5509.8, and 1382.0 per 100,000 people, respectively, and the age-standardized rate was 4903.8, 4041.7, and 990.9 per 100,000 people. Among the overall stroke population, 13.4% were living with consequences of stroke. Hypertension (86.7%), dyslipidemia (37.2%), and diabetes (24.5%) were highly prevalent in stroke participants. However, most of those comorbidities remained uncontrolled (93.7, 44.7, and 88.9%, respectively). Conclusion The burden of stroke in rural northeast China was substantial, with a high prevalence of stroke, recurrence, and disabilities. Uncontrolled comorbidities will likely contribute to recurrence and worsening disabilities in the coming decades. Strategies of long-term management of stroke and related risk factors are urgently required in rural northeast China.

Age-Related Risk Factors for Ischemic Stroke in Italian Men

1994 ◽  
Vol 13 (1-2) ◽  
pp. 28-33 ◽  
Author(s):  
Pietro B. Carrieri ◽  
Giuseppe Orefice ◽  
Antonio Maiorino ◽  
Vincenzo Provitera ◽  
Giuseppe BaIzano ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Age Related ◽  
Related Risk

scholarly journals Potential Role of Melatonin as an Adjuvant for Atherosclerotic Carotid Arterial Stenosis

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 811
Author(s):  
Rui Zhang ◽  
Leng Ni ◽  
Xiao Di ◽  
Baitao Ma ◽  
Shuai Niu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Carotid Artery ◽  
Endothelial Damage ◽  
Arterial Stenosis ◽  
Arterial Lumen ◽  
Arterial Plaque ◽  
Related Risk ◽  
Cerebral Ischemic ◽  
Cerebral Ischemic Reperfusion

Carotid artery stenosis (CAS) is an atherosclerotic disease characterized by a narrowing of the artery lumen and a high risk of ischemic stroke. Risk factors of atherosclerosis, including smoking, hypertension, hyperglycemia, hyperlipidemia, aging, and disrupted circadian rhythm, may potentiate atherosclerosis in the carotid artery and further reduce the arterial lumen. Ischemic stroke due to severe CAS and cerebral ischemic/reperfusion (I/R) injury after the revascularization of CAS also adversely affect clinical outcomes. Melatonin is a pluripotent agent with potent anti-inflammatory, anti-oxidative, and neuroprotective properties. Although there is a shortage of direct clinical evidence demonstrating the benefits of melatonin in CAS patients, previous studies have shown that melatonin may be beneficial for patients with CAS in terms of reducing endothelial damage, stabilizing arterial plaque, mitigating the harm from CAS-related ischemic stroke and cerebral I/R injury, and alleviating the adverse effects of the related risk factors. Additional pre-clinical and clinical are required to confirm this speculation.

Role of pulse oximetric monitoring during gastrointestinal endoscopy. Prospective multicenter study of the Gastroenterological Working Group of the Veszprém Regional Committee of the Hungarian Academy of Sciences (VEAB)

2013 ◽  
Vol 154 (21) ◽  
pp. 825-833
Author(s):  
Zoltán Döbrönte ◽  
Mária Szenes ◽  
Beáta Gasztonyi ◽  
Lajos Csermely ◽  
Márta Kovács ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multicenter Study ◽  
Hungarian Academy ◽  
Prospective Multicenter Study ◽  
Standard Requirement ◽  
Long Duration ◽  
Related Risk ◽  
American Society ◽  
Academy Of Sciences ◽  
Endoscopic Investigation

Introduction: Recent guidelines recommend routine pulse oximetric monitoring during endoscopy, however, this has not been the common practice yet in the majority of the local endoscopic units. Aims: To draw attention to the importance of the routine use of pulse oximetric recording during endoscopy. Method: A prospective multicenter study was performed with the participation of 11 gastrointestinal endoscopic units. Data of pulse oximetric monitoring of 1249 endoscopic investigations were evaluated, of which 1183 were carried out with and 66 without sedation. Results: Oxygen saturation less than 90% was observed in 239 cases corresponding to 19.1% of all cases. It occurred most often during endoscopic retrograde cholangiopancreatography (31.2%) and proximal enteroscopy (20%). Procedure-related risk factors proved to be the long duration of the investigation, premedication with pethidine (31.3%), and combined sedoanalgesia with pethidine and midazolam (34.38%). The age over 60 years, obesity, consumption of hypnotics or sedatives, severe cardiopulmonary state, and risk factor scores III and IV of the American Society of Anestwere found as patient-related risk factors. Conclusion: To increase the safety of patients undergoing endoscopic investigation, pulse oximeter and oxygen supplementation should be the standard requirement in all of the endoscopic investigation rooms. Pulse oximetric monitoring is advised routinely during endoscopy with special regard to the risk factors of hypoxemia. Orv. Hetil., 2013, 154, 825–833.

500-P: Renal Function Decline and the Related Risk Factors in a Cohort of Beijing Community Diabetes Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 500-P
Author(s):  
MINGXIA YUAN ◽  
SHENYUAN YUAN ◽  
Keyword(s):  
Risk Factors ◽  
Renal Function ◽  
Renal Function Decline ◽  
Related Risk
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