Role of the functional SYNTAX score in evaluating multivessel coronary artery disease

2011 ◽  
Vol 3 (6) ◽  
pp. 695-704 ◽  
Author(s):  
Chang-Wook Nam ◽  
William F Fearon
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Syntax Score ◽  
Multivessel Coronary Artery Disease ◽  
Artery Disease ◽  
Functional Syntax

scholarly journals Functional SYNTAX Score for Risk Assessment in Multivessel Coronary Artery Disease

2011 ◽  
Vol 58 (12) ◽  
pp. 1211-1218 ◽  
Author(s):  
Chang-Wook Nam ◽  
Fabio Mangiacapra ◽  
Robert Entjes ◽  
In-Sung Chung ◽  
Jan-Willem Sels ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Syntax Score ◽  
Multivessel Coronary Artery Disease ◽  
Artery Disease ◽  
Functional Syntax

scholarly journals Predictive Performance of SYNTAX Score II in Patients With Left Main and Multivessel Coronary Artery Disease

2014 ◽  
Vol 78 (8) ◽  
pp. 1942-1949 ◽  
Author(s):  
Carlos M. Campos ◽  
David van Klaveren ◽  
Javaid Iqbal ◽  
Yoshinobu Onuma ◽  
Yao-Jun Zhang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Predictive Performance ◽  
Syntax Score ◽  
Multivessel Coronary Artery Disease ◽  
Left Main ◽  
Syntax Score Ii ◽  
Artery Disease

1155Prognostic impact of SYNTAX Score in patients with myocardial infarction with multivessel coronary artery disease and cardiogenic shock: insight from the CULPRIT-SHOCK Trial

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
P Guedeney ◽  
O Barthelemy ◽  
M Zeitouni ◽  
M Hauguel-Moreau ◽  
G Hage ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Syntax Score ◽  
Shock Trial ◽  
Multivessel Coronary Artery Disease ◽  
Risk Of Death ◽  
Artery Disease

Abstract Background The majority of patients presenting with myocardial infarction (MI) and cardiogenic shock (CS) have multivessel coronary artery disease. The prognosis impact of the SYNTAX score (SS) in this setting remains unknown. Purpose To evaluate the prognosis value of the SS in this high-risk population undergoing percutaneous coronary intervention (PCI) Methods The CULPRIT-SHOCK trial was an international, open-label trial, where patients presenting with MI and multivessel disease complicated by CS were randomized to a culprit-lesion-only or an immediate multivessel PCI strategy. Pre-PCI SS was assessed by a central core laboratory and patients were categorized as low SS (SS ≤22), intermediate SS (22<SS≤32) and high SS (SS>32). Adjudicated endpoints of interest were the risks of all-cause death or renal replacement therapy at 30 days and all-cause death at 1 year. Associations between SYNTAX score and outcomes were assessed using multivariate logistic regression. Results SS was available in 632 patients, of whom 265 (41.9%), 211 (33.4%) and 156 (24.7%) presented with low, intermediate and high SS, respectively. Patients with higher SS were older, with more frequent peripheral artery disease, less current smoking, lower creatinine clearance, and higher use of catecholamine. A stepwise increase in the incidence of adverse events transitioning from low to intermediate and high SS was observed with the 30-day risk of death or renal replacement therapy as well as the 1-year risk of all-cause death (p for trend <0.001, for all). After multiple adjustment, intermediate and high SS remained strongly associated with 30-day risk of death and renal replacement therapy and 1-year risk of all-cause death (Figure). There was no significant interaction between SYNTAX score and the coronary revascularization strategy for all endpoints. Conclusion In patients presenting with acute MI, multivessel disease and CS, the SYNTAX score was strongly associated to 30-day and 1-year mortality</ss≤<ss≤32)> Acknowledgement/Funding The CULPRIT-SHOCK trial was Supported by a grant agreement (602202) from the European Union Seventh Framework Program and by the German Heart Research

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