scholarly journals Acquired inducible antimicrobial resistance in Gram-positive bacteria

2012 ◽  
Vol 7 (8) ◽  
pp. 959-978 ◽  
Author(s):  
Scott T Chancey ◽  
Dorothea Zähner ◽  
David S Stephens
Keyword(s):  
Antimicrobial Resistance ◽  
Gram Positive ◽  
Gram Positive Bacteria

scholarly journals Re-thinking antimicrobial resistance transmission dynamics: a meta-analysis of cross-sectional studies at referral hospitals in Uganda

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 878
Author(s):  
Gerald Mboowa ◽  
Ivan Sserwadda ◽  
Dickson Aruhomukama
Keyword(s):  
Antimicrobial Resistance ◽  
Transmission Dynamics ◽  
Gram Positive ◽  
Cross Sectional ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Extended Spectrum ◽  
Hospital Environments ◽  
Referral Hospitals ◽  
Cross Sectional Studies

Background: Antimicrobial resistance threatens the achievements of modern medicine as well as the sustainability of effective global public health responses to the threat posed by infectious diseases. Extended-spectrum β-lactamase production in bacteria provides the main mechanism of resistance in gram-negative bacteria, particularly those belonging to the Enterobacteriaceae family as well as gram-positive bacteria. This study hence aimed at providing insights into the potential role of in-patients, their immediate hospital environments, out-patients, and their communities in the transmission of antimicrobial resistance via identifying gram-negative and gram-positive bacteria commonly isolated in samples collected from each of these patients/sites as well as their antimicrobial susceptibility profiles using extended-spectrum β-lactamase production in the same as the basis. Methods: Our study reviewed four cross-sectional studies conducted at national and regional referral hospitals in Uganda. Data on bacterial aetiology and antimicrobial susceptibility testing retrieved from the studies was imported into Microsoft Excel, cleaned, sand then exported to IBM SPSS statistics (version 16) for statistical analysis. The databases used were PubMed and Embase.  Results: We report that; Escherichia coli and Klebsiella pneumoniae are the most prevalent Enterobacteriaceae species in the samples that were collected in the studies reviewed; these species account for the highest proportions of extended-spectrum β-lactamase producers; Staphylococcus aureus is the most prevalent of the gram-positive bacteria isolated from the same samples, and accounts for the highest proportions of extended-spectrum β-lactamase producers in the gram-positive bacteria isolated, and similar Enterobacteriaceae species and gram-positive bacteria, are predominant in samples from in-patients, their immediate hospital environments, and out-patients. Conclusion: The insights provided indicate antimicrobial resistance transmission dynamics be re-thought and more comprehensive studies aimed at investigating the same be done to ascertain the source and transmission routes of antimicrobial-resistant bacteria in clinical settings.

An alpha/beta chimeric peptide molecular brush for eradicating MRSA biofilms and persister cells to mitigate antimicrobial resistance

2020 ◽  
Vol 8 (24) ◽  
pp. 6883-6889 ◽  
Author(s):  
Ximian Xiao ◽  
Si Zhang ◽  
Sheng Chen ◽  
Yuxin Qian ◽  
Jiayang Xie ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Drug Resistant ◽  
Excellent Performance ◽  
Persister Cells ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Chimeric Peptide ◽  
Alpha Beta ◽  
Chimeric Polypeptide

An α/β chimeric polypeptide molecular brush shows excellent performance in eradicating established biofilms, persister cells, and clinically isolated multi-drug resistant Gram-positive bacteria.

Multifunctional BODIPY for effective inactivation of Gram-positive bacteria and promotion of wound healing

2021 ◽  
Author(s):  
Chaonan Li ◽  
Yite Li ◽  
Qihang Wu ◽  
Tingting Sun ◽  
Zhigang Xie
Keyword(s):  
Wound Healing ◽  
Photodynamic Therapy ◽  
Antimicrobial Resistance ◽  
Infectious Diseases ◽  
Human Health ◽  
Bacterial Infections ◽  
Alternative Therapies ◽  
Gram Positive ◽  
Gram Positive Bacteria

Bacterial infectious diseases and antimicrobial resistance seriously endanger human health, so alternative therapies for bacterial infections are urgently needed. Recently, photodynamic therapy against bacteria has shown great potential because of...

scholarly journals Antimicrobial resistance rates in gram-positive bacteria do not drive glycopeptides use

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0181358 ◽  
Author(s):  
Beryl Primrose Gladstone ◽  
Andrea Cona ◽  
Parichehr Shamsrizi ◽  
Tuba Vilken ◽  
Winfred V. Kern ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Resistance Rates
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