scholarly journals On the road to systems biology of host–pathogen interactions

2010 ◽  
Vol 5 (2) ◽  
pp. 131-133 ◽  
Author(s):  
Klaus Früh ◽  
Brett Finlay ◽  
Grant McFadden
Keyword(s):  
Systems Biology ◽  
Host Pathogen Interactions ◽  
The Road ◽  
Host Pathogen ◽  
On The Road

scholarly journals Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind

2012 ◽  
Vol 8 (11) ◽  
pp. e1003007 ◽  
Author(s):  
Elena Gómez-Díaz ◽  
Mireia Jordà ◽  
Miguel Angel Peinado ◽  
Ana Rivero
Keyword(s):  
Host Pathogen Interactions ◽  
The Road ◽  
Host Pathogen

Uncovering complex molecular networks in host–pathogen interactions using systems biology

2019 ◽  
Vol 3 (4) ◽  
pp. 371-378
Author(s):  
Joshua M. Peters ◽  
Sydney L. Solomon ◽  
Christopher Y. Itoh ◽  
Bryan D. Bryson
Keyword(s):  
Systems Biology ◽  
High Throughput ◽  
Cell Biology ◽  
Molecular Networks ◽  
Host Pathogen Interactions ◽  
Exciting Field ◽  
Specific Host ◽  
Biomolecular Network ◽  
Host Pathogen ◽  
Analytical Frameworks

Abstract Interactions between pathogens and their hosts can induce complex changes in both host and pathogen states to privilege pathogen survival or host clearance of the pathogen. To determine the consequences of specific host–pathogen interactions, a variety of techniques in microbiology, cell biology, and immunology are available to researchers. Systems biology that enables unbiased measurements of transcriptomes, proteomes, and other biomolecules has become increasingly common in the study of host–pathogen interactions. These approaches can be used to generate novel hypotheses or to characterize the effects of particular perturbations across an entire biomolecular network. With proper experimental design and complementary data analysis tools, high-throughput omics techniques can provide novel insights into the mechanisms that underlie processes from phagocytosis to pathogen immune evasion. Here, we provide an overview of the suite of biochemical approaches for high-throughput analyses of host–pathogen interactions, analytical frameworks for understanding the resulting datasets, and a vision for the future of this exciting field.

GENOMICS: DOE Hits Potholes on the Road to Systems Biology

Science ◽  
2006 ◽  
Vol 311 (5765) ◽  
pp. 1226a-1226a
Author(s):  
E. Pennisi
Keyword(s):  
Systems Biology ◽  
The Road ◽  
On The Road

Using a Systems Biology Approach To Study Host-Pathogen Interactions

2020 ◽  
pp. 337-347
Author(s):  
Amy Yeung ◽  
Christine Hale ◽  
Simon Clare ◽  
Sophie Palmer ◽  
Josefin Bartholdson Scott ◽  
...  
Keyword(s):  
Systems Biology ◽  
Host Pathogen Interactions ◽  
Host Pathogen

Using a Systems Biology Approach To Study Host-Pathogen Interactions

2019 ◽  
pp. 349-356 ◽  
Author(s):  
Amy Yeung ◽  
Christine Hale ◽  
Simon Clare ◽  
Sophie Palmer ◽  
Josefin Bartholdson Scott ◽  
...  
Keyword(s):  
Systems Biology ◽  
Host Pathogen Interactions ◽  
Host Pathogen

scholarly journals The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria

2017 ◽  
Vol 8 ◽  
Author(s):  
Meghan Zuck ◽  
Laura S. Austin ◽  
Samuel A. Danziger ◽  
John D. Aitchison ◽  
Alexis Kaushansky
Keyword(s):  
Systems Biology ◽  
Host Pathogen Interactions ◽  
Host Pathogen

scholarly journals Challenges and rewards on the road to translational systems biology in acute illness: four case reports from interdisciplinary teams

2007 ◽  
Vol 22 (2) ◽  
pp. 169-175 ◽  
Author(s):  
Gary An ◽  
C. Anthony Hunt ◽  
Gilles Clermont ◽  
Edmund Neugebauer ◽  
Yoram Vodovotz
Keyword(s):  
Systems Biology ◽  
Case Reports ◽  
Acute Illness ◽  
Interdisciplinary Teams ◽  
The Road ◽  
On The Road

Community Colleges: Vital Partners on the Road to Diversity

ASHA Leader ◽  
2006 ◽  
Vol 11 (5) ◽  
pp. 14-17 ◽  
Author(s):  
Shelly S. Chabon ◽  
Ruth E. Cain
Keyword(s):  
Community Colleges ◽  
The Road ◽  
On The Road
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