An overview of valvular heart disease in the elderly

Author(s):  
Erwan Flécher ◽  
Thierry Langanay ◽  
Alain Leguerrier
2016 ◽  
Vol 8 (12) ◽  
pp. E1701-E1703 ◽  
Author(s):  
Yan Chen ◽  
Kai-Hang Yiu

2020 ◽  
Vol 36 (7) ◽  
pp. 1104-1111 ◽  
Author(s):  
Gabriele Crimi ◽  
Claudio Montalto ◽  
Luca Angelo Ferri ◽  
Luigi Piatti ◽  
Irene Bossi ◽  
...  

1986 ◽  
Vol 4 (2) ◽  
pp. 263-272 ◽  
Author(s):  
Nanette K. Wenger

2011 ◽  
Vol 5 (5) ◽  
pp. 413-421 ◽  
Author(s):  
Peter J. Cawley ◽  
Catherine M. Otto

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Darshan Krishnappa ◽  
Richard Dykoski ◽  
Ilknur Can ◽  
Mackenzie Mbai ◽  
Inder S. Anand ◽  
...  

Abstract Amyloid infiltration of the atrium is described in patients with valvular heart disease and is associated with an increased risk for atrial fibrillation(AF) while amyloid deposits in the ventricles is increasingly being diagnosed in patients with HFpEF. The role of amyloid deposits in patients with AF without valvular heart disease, which represents the most common form of AF globally, is undefined. In this study, we sought to assess the prevalence of sub-clinical isolated cardiac amyloidosis (ICA) at autopsy and the odds of AF in these patients. A total of 1083 patients were included in the study and 3.1% of patients were found to have asymptomatic ICA. Patients with ICA were older and had a higher odds of AF independent of age and CHA2DS2VASc score. Amongst patients with AF, those with ICA were more likely to have persistent forms of AF and had a lower sinus rhythm P-wave amplitude. Further studies are required to further define this entity, identify imaging modalities to aid in antemortem diagnosis of ICA and to establish the optimal management strategies in these patients.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ying Yang ◽  
Zengwu Wang ◽  
Zuo Chen ◽  
Xin Wang ◽  
Linfeng Zhang ◽  
...  

Abstract Background The epidemiology of valvular heart disease (VHD) has changed markedly over the last 50 years worldwide, and the prevalence and features of VHD in China are unknown. The objective of this study was to investigate the current status and etiology of VHD in China. Methods We used a cross-sectional national survey with stratified multistage random sampling from the general Chinese population to estimate the VHD burden. Data on demographic characteristics, medical history, physical examination, blood tests, and potential etiology were collected. Echocardiography was used to detect VHD. Results The national survey enrolled 34,994 people aged 35 years or older across China. Overall, 31,499 people were included in the final analysis, and 1309 participants were diagnosed with VHD. The weighted prevalence was 3.8%, with an estimated 25 million patients in China. The prevalence of VHD increased with age and was higher in participants with hypertension or chronic kidney disease than in their counterparts. Among participants with VHD, 55.1% were rheumatic and 21.3% were degenerative. The proportion of rheumatic decreased with age, and the proportion of degenerative rose with age. However, the prevalence of rheumatic disease was still higher in the elderly population than in the younger population. Logistic regression revealed that age and hypertension were correlated with VHD. Conclusions In China, rheumatic heart disease was still the major cause of the VHD, with a significant increase in degenerative heart disease. Age and hypertension are important and easily identifiable markers of VHD.


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