scholarly journals EVALUATION OF THE EFFECT OF RESOURCE CIRCULATION BY AN ALTERNATIVE RECYCLING TECHNOLOGY-COMPARISON BETWEEN HORIZONTAL RECYCLING AND CASCADE RECYCLING OF WOOD RESOURCE-

2008 ◽  
Vol 36 ◽  
pp. 275-280
Author(s):  
Minoru FUJII ◽  
Emiri NAGASAWA ◽  
Tsuyoshi FUJITA ◽  
Shizuka HASHIMOTO
Author(s):  
A.V. Stomatov ◽  
D.V. Stomatov ◽  
P.V. Ivanov ◽  
V.V. Marchenko ◽  
E.V. Piitsky ◽  
...  

In this work, the authors studied and compared the two main methods used in dental practice for the automated production of orthopedic structures: the widely used CAD / CAM milling method and the 3D printing technology. As an object of research, temporary crowns were used, which were made on the basis of the same digital model: a) by the method of CAD / CAM milling from polymethylmethacrylate disks; b) by 3D printing from photopolymer resin based on LCD technology. Comparison of production methods and finished designs was carried out according to the following characteristics: strength, durability, aesthetic qualities, accuracy of orthopedic designs, etc. According to the results of the study, it was concluded that 3D printing can be a good alternative to CAD / CAM milling in solving problems of temporary prosthetics.


2020 ◽  
Vol 27 (25) ◽  
pp. 4157-4164 ◽  
Author(s):  
Taku Fukuzawa ◽  
Junichi Nezu

Background: The complement system usually helps protect against microbial infection, but it could also be involved in the onset of various diseases. Inhibition of complement component 5 (C5) with eculizumab has resulted in a significant reduction of hemolysis, reduction of thromboembolic events, and increased survival in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH). However, eculizumab requires frequent intravenous infusions due to the abundance of C5 in plasma and some patients may still experience breakthrough hemolysis. This review introduces the recent body of knowledge on recycling technology and discusses the likely therapeutic benefits of SKY59, a novel recycling antibody, for PNH and complement-mediated disorders. Methods: By using recycling technology, we created a novel anti-C5 antibody, SKY59, capable of binding to C5 pH-dependently. Results: In cynomolgus monkeys, SKY59 robustly inhibited C5 and complement activity for significantly longer than a conventional antibody. SKY59 also showed an inhibitory effect on C5 variant p.Arg885His, whereas eculizumab does not suppress complement activity in patients with this type of mutation. Conclusion: SKY59 is a promising anti-C5 biologic agent that has significant advantages over current therapies such as long duration of action and efficacy against C5 variants.


Author(s):  
Antonio Creta ◽  
Viijayabharathy Kanthasamy ◽  
Richard J. Schilling ◽  
James Rosengarten ◽  
Fakhar Khan ◽  
...  

Recycling ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. 31
Author(s):  
Linda Gaines ◽  
Qiang Dai ◽  
John T. Vaughey ◽  
Samuel Gillard

The expected rapid growth in electric vehicle deployment will inevitably be followed by a corresponding rise in the supply of end-of-life vehicles and their lithium-ion batteries (LIBs). The batteries may be reused, but will eventually be spent and provide a potential domestic resource that can help supply materials for future battery production. However, commercial recycling processes depend on profits from recovery of cobalt, use of which is being reduced in new cathode chemistries. The U.S. Department of Energy, therefore, established the ReCell Center in early 2019 to develop robust LIB recycling technology that would be economical even for batteries that contain no cobalt. The central feature of the technology is recovery of the cathode material with its unique crystalline cathode morphology intact in order to retain its value and functionality. Other materials are recovered as well in order to maximize revenues and minimize waste-handling costs. Analysis and modeling serve to evaluate and compare process options so that we can identify those that will be most economical while still minimizing energy use and environmental impacts. This paper provides background and describes highlights of the center’s first 2 years of operation.


Author(s):  
Shinichi Fukushige ◽  
Yuki Matsuyama ◽  
Eisuke Kunii ◽  
Yasushi Umeda

Within the framework of sustainability in manufacturing industry, product lifecycle design is a key approach for constructing resource circulation systems of industrial products that drastically reduce environmental loads, resource consumption and waste generation. In such design, designers should consider both a product and its lifecycle from a holistic viewpoint, because the product’s structure, geometry, and other attributes are closely coupled with the characteristics of the lifecycle. Although product lifecycle management (PLM) systems integrate product data during its lifecycle into one data architecture, they do not focus on support for lifecycle design process. In other words, PLM does not provide explicit models for designing product lifecycles. This paper proposes an integrated model of a product and its lifecycle and a method for managing consistency between the two. For the consistency management, three levels of consistency (i.e., topological, geometric, and semantic) are defined. Based on this management scheme, the product lifecycle model allows designers to evaluate environmental, economic, and other performance of the designed lifecycle using lifecycle simulation.


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