Impact of masticatory behaviors measured with wearable device on metabolic syndrome (Preprint)

2021 ◽  
Author(s):  
Fumiko Uehara ◽  
Kazuhiro Hori ◽  
Yoko Hasegawa ◽  
Shogo Yoshimura ◽  
Shoko Hori ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Energy Intake ◽  
Medical Information ◽  
Wearable Device ◽  
University Hospital ◽  
Abdominal Circumference ◽  
Whole Body ◽  
Data Repository ◽  
Small Scale

BACKGROUND It has been widely recognized that the mastication behaviors are related to the health of the whole body such as lifestyle-related disease. However, many studies were based on subjective questionnaire, or were limited to small-scale research in the laboratory due to the lack of device for measuring mastication behaviors of daily meal objectively. Recently, a small wearable masticatory counter device, called bitescan, for measuring masticatory behavior was developed. This wearable device is designed to assess objective masticatory behavior just by putting on the ear in not only laboratory but also in usual situations. OBJECTIVE This study aimed to compare mastication behaviors in the laboratory with that in daily meals and to clarify the relation between mastication behaviors measured by wearable device and metabolic syndrome (MetS). METHODS Ninety-nine healthy volunteers (50 men and 49 women, 36.4 ± 11.7y) participated in this study. The mastication behaviors i.e. number chews and bite, number of chews per bite, chewing rate were measured using the wearable ear-hung type device. Mastication behaviors during eating a rice ball (100 g) in the laboratory and during usual meals for an entire day were monitored, and the daily energy intake was calculated. Participants’ abdominal circumference, fasting glucose concentration, blood pressure, and serum lipids were also measured. The mastication behaviors in laboratory and in meals for one entire day was compared. The participants were divided into two groups using Japanese criteria for MetS (positive / negative for MetS or each MetS components), and mastication behaviors was compared. RESULTS Mastication behaviors in the laboratory and during daily meals were significantly correlated (number of chews r=.360; P<.001, number of bites r=.493; P<.001, number of chews per bite r=.334; P=.001, chewing rate r=.512; P<.001). Although a positive correlation was observed between the number of chews during the 1-day meals and energy intake (r=.262, P=.009), the number of chews per calorie ingested was negatively correlated with energy intake (r=-.315, P=.002). Eight participants were diagnosed with MetS and 12 with pre-MetS. The number of chews and bites for a rice ball in pre-MetS (+) group was significantly lower than the pre-MetS (-) group (P=.016, P=.027, respectively). Additionally, these scores for the positive abdominal circumference, and blood pressure subgroup were also less than the counterpart groups (P=.006, P=.010 for chews, P=.006, P=.016 for bites, respectively). The number of chews and bites for an entire day in the hypertension subgroup were significantly lower than in the other groups (P=.020, P=.006). Furthermore, the positive abdominal circumference and hypertension subgroups showed lower number of chews per calorie ingested, for 1-day meals (P=.049, P=.021, respectively). CONCLUSIONS These results suggested that masticatory behaviors do not change with environmental, and that masticatory behaviors might have relation to MetS and MetS components. CLINICALTRIAL A protocol containing all methods and materials was uploaded to the Individual Case Data Repository of University Hospital Medical Information Network, prior to the start of data collection (https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000034453).

The Effects of a Modified High-carbohydrate High-fat Diet on Metabolic Syndrome Parameters in Male Rats

2017 ◽  
Vol 126 (04) ◽  
pp. 205-212 ◽  
Author(s):  
Sok Wong ◽  
Kok-Yong Chin ◽  
Farihah Suhaimi ◽  
Fairus Ahmad ◽  
Soelaiman Ima-Nirwana
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
High Fat Diet ◽  
Normal Group ◽  
Male Rats ◽  
Abdominal Circumference ◽  
Whole Body ◽  
High Fat ◽  
Southeast Asians ◽  
High Carbohydrate

AbstractMetabolic syndrome is a cluster of metabolic abnormalities including central obesity, hyperglycemia, hypertension, and dyslipidemia. A previous study has established that high-carbohydrate high-fat diet (HCHF) can induce MetS in rats. In this study, we modified components of the diet so that it resembled the diet of Southeast Asians. This study aimed to determine the effects of this modified HCHF diet on metabolic parameters in rats. Male Wistar rats (n=14) were randomised into two groups. The normal group was given standard rat chow. The MetS group was given the HCHF diet, comprises of fructose, sweetened condensed milk, ghee, Hubble Mendel and Wakeman salt mixture, and powdered rat food. The diet regimen was assigned for a period of 16 weeks. Metabolic syndrome parameters (abdominal circumference, blood glucose, blood pressure, and lipid profile) were measured at week 0, 8, 12, and 16 of the study. The measurement of whole body composition (fat mass, lean mass, and percentage of fat) was performed using dual-energy X-ray absorptiometry at week 0, 8, and 16. Our results indicated that the components of MetS were partially developed after 8 weeks of HCHF diet. Systolic blood pressure, triglyceride, low density lipoprotein cholesterol, fat content, and percentage of fat was significantly higher in the HCHF group compared to normal group (p<0.05). After 12 weeks of HCHF diet, the rats showed significant increases in abdominal circumference, blood pressure, glucose intolerance, and dyslipidemia compared to normal control (p<0.05). In conclusion, MetS is successfully established in male rats induced by the modified HCHF diet after 12 weeks.

scholarly journals Rind from Purple Mangosteen (Garcinia mangostana) Attenuates Diet-Induced Physiological and Metabolic Changes in Obese Rats

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 319
Author(s):  
Oliver D. John ◽  
Peter Mouatt ◽  
Sunil K. Panchal ◽  
Lindsay Brown
Keyword(s):  
Metabolic Syndrome ◽  
Inflammatory Cells ◽  
Left Ventricular ◽  
Metabolic Changes ◽  
Abdominal Circumference ◽  
Whole Body ◽  
Garcinia Mangostana ◽  
Tropical Fruit ◽  
Cardiovascular Parameters ◽  
Left Ventricular Stiffness

The pulp of the purple mangosteen, Garcinia mangostana, is a popular tropical fruit but the rind containing xanthones such as α-mangostin together with procyanidins and anthocyanidins is usually discarded as waste. However, this rind has been used in South-East Asia for diarrhoea, dysentery, skin infections and wounds. As xanthones have reported anti-inflammatory and antioxidant responses, this study has determined the bioactive compounds and evaluated the effects of G. mangostana rind on physiological, metabolic, liver and cardiovascular parameters in rats with diet-induced metabolic syndrome. Rats fed a diet with increased simple sugars and saturated fats developed obesity, hypertension, increased left ventricular stiffness, dyslipidaemia and fatty liver. Administration of G. mangostana rind as 5% of the food to rats with diet-induced metabolic syndrome gave a dose of 168 mg/kg/day α-mangostin, 355 mg/kg/day procyanidins, 3.9 mg/kg/day anthocyanins and 11.8 mg/kg/day hydroxycitric acid for 8 weeks which reduced body weight and attenuated physiological and metabolic changes in rats including decreased abdominal fat deposition, decreased abdominal circumference and whole-body fat mass, improved liver structure and function and improved cardiovascular parameters such as systolic blood pressure, left ventricular stiffness and endothelial function. These responses were associated with decreased infiltration of inflammatory cells, decreased deposition of collagen in both heart and liver and decreased mean adipocyte size in retroperitoneal adipose tissues. We conclude that, in rats with diet-induced metabolic syndrome, chronic intake of G. mangostana rind decreased infiltration of inflammatory cells which decreased physiological, metabolic, liver and cardiovascular symptoms.

scholarly journals Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study

2020 ◽  
Vol 150 (12) ◽  
pp. 3161-3170
Author(s):  
Alicia Julibert ◽  
Maria del Mar Bibiloni ◽  
Laura Gallardo-Alfaro ◽  
Manuela Abbate ◽  
Miguel Á Martínez-González ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Energy Intake ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Virgin Olive Oil ◽  
Hdl Cholesterol ◽  
Excess Weight ◽  
Study Cohort

ABSTRACT Background High nut consumption has been previously associated with decreased prevalence of metabolic syndrome (MetS) regardless of race and dietary patterns. Objectives The aim of this study was to assess whether changes in nut consumption over a 1-y follow-up are associated with changes in features of MetS in a middle-aged and older Spanish population at high cardiovascular disease risk. Methods This prospective 1-y follow-up cohort study, conducted in the framework of the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial, included 5800 men and women (55–75 y old) with overweight/obesity [BMI (in kg/m2) ≥27 and &lt;40] and MetS. Nut consumption (almonds, pistachios, walnuts, and other nuts) was assessed using data from a validated FFQ. The primary outcome was the change from baseline to 1 y in features of MetS [waist circumference (WC), glycemia, HDL cholesterol, triglyceride (TG), and systolic and diastolic blood pressure] and excess weight (body weight and BMI) according to tertiles of change in nut consumption. Secondary outcomes included changes in dietary and lifestyle characteristics. A generalized linear model was used to compare 1-y changes in features of MetS, weight, dietary intakes, and lifestyle characteristics across tertiles of change in nut consumption. Results As nut consumption increased, between each tertile there was a significant decrease in WC, TG, systolic blood pressure, weight, and BMI (P &lt; 0.05), and a significant increase in HDL cholesterol (only in women, P = 0.044). The interaction effect between time and group was significant for total energy intake (P &lt; 0.001), adherence to the Mediterranean diet (MedDiet) (P &lt; 0.001), and nut consumption (P &lt; 0.001). Across tertiles of increasing nut consumption there was a significant increase in extra virgin olive oil intake and adherence to the MedDiet; change in energy intake, on the other hand, was inversely related to consumption of nuts. Conclusions Features of MetS and excess weight were inversely associated with nut consumption after a 1-y follow-up in the PREDIMED-Plus study cohort. This trial was registered at isrctn.com as ISRCTN89898870.

Abstract P247: Gut Microbiota From A Rat Model Of Metabolic Syndrome Lowers Fitness Of High Exercise Capacity Rats (HCR/ Tol ) By Impairing Energy Homeostasis And Increasing Blood Pressure

Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
Guannan Zhou ◽  
Tao Yang ◽  
Sivarajan Kumarasamy ◽  
Bina Joe ◽  
Lauren G Koch
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Energy Metabolism ◽  
Gut Microbiota ◽  
Exercise Capacity ◽  
Energy Homeostasis ◽  
Current Knowledge ◽  
Strong Predictor ◽  
Whole Body ◽  
Acid Oxidation

Introduction: Low exercise capacity is a strong predictor of cardiovascular disease and overall mortality. Previously we have shown that rats artificially selected for low intrinsic exercise capacity (LCR) have reduced longevity and develop features consistent with metabolic syndrome (MetS) compared to high intrinsic exercise capacity rats (HCR). Current knowledge suggests that gut microbiota is an important contributor for host fitness. Thus, we hypothesized that transferring gut microbiota from LCR rats into inbred high capacity runner (HCR /Tol ) rats would increase risk factors for MetS, including high blood pressure (BP), gain in body weight (BW), and altered resting energy metabolism. Methods: Gut microbiota was depleted in male HCR/ Tol rats (4 mo.) by an antibiotic cocktail given orally (50mg/kg of BW/day) for 5 days, followed by weekly fecal microbiota transfer (FMT) from male LCR or HCR rats (13 mo.) to generate HCR/ Tol -LCR FMT (n = 5) or HCR/ Tol -HCR FMT (n = 6) groups. BW was measured every 4 weeks. At week 11, whole body metabolism was measured by indirect calorimetry (Oxymax, Columbus Instruments). Respiratory Exchange Ratio (RER), Energy Expenditure (EE), glucose and fat oxidation were calculated from oxygen consumption and carbon dioxide release (VO 2 and VCO 2 ). At week 12, BP was measured by tail-cuff method (Kent Scientific) and treadmill exercise test was done at week 13. Results: Compared to HCR/ Tol -HCR FMT , HCR/ Tol -LCR FMT showed a significant gain in BW (7.2% vs 1.9%, P<0.05), elevated systolic BP (147 vs 120 mmHg, P<0.0001), diastolic BP (112 vs 91 mmHg, P<0.01), and mean BP (123 vs 100 mmHg, P<0.001). BP changes in HCR/ Tol -LCR FMT associated with 1) increased VO 2 (355 vs 320 ml/hr, P<0.05), 2) elevated VCO 2 (350 vs 298 ml/hr, P<0.01), 3) increased EE (1.8 vs 1.6 kcal/hr, P<0.01), 4) higher RER (0.96 vs 0.91, P<0.001), 5) higher glucose oxidation (1.36 vs 1.12 g/kg/hr, P<0.001) and 6) reduced fatty acid oxidation (0.09 vs 0.15 g/kg/hr, P<0.01) and a 23% lower exercise capacity. Conclusions: Gut microbiota from LCR rats strongly associated with poor health outcomes, notably elevated BP and impaired energy metabolism. These findings suggest that altered energy homeostasis by microbiota is mechanistically linked to host BP regulation within MetS.

scholarly journals Prevalence of metabolic components in university students

2014 ◽  
Vol 22 (6) ◽  
pp. 1041-1047 ◽  
Author(s):  
Ana Roberta Vilarouca da Silva ◽  
Luana Savana Nascimento de Sousa ◽  
Telma de Sousa Rocha ◽  
Ramiro Marx Alves Cortez ◽  
Layla Gonçalves do Nascimento Macêdo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Fasting Blood Glucose ◽  
Significant Proportion ◽  
Hdl Cholesterol ◽  
Clinical Analysis ◽  
Abdominal Circumference ◽  
Sample Collection ◽  
Glucose Levels ◽  
Low Hdl

OBJECTIVE: to identify the frequency of components of Metabolic Syndrome (MetS) among university students.METHOD: descriptive study with 550 students, from various courses run by a public university. The socioeconomic data, lifestyle, and components of MetS were filled out using a questionnaire. Blood sample collection was undertaken in the university itself by a contracted clinical analysis laboratory.RESULTS: 66.2% were female, with a mean age of 22.6±4.41; 71.7% were sedentary; 1.8% stated that they smoke; and 48.5% were classified as at medium risk for alcoholism. 5.8% had raised abdominal circumference and 20.4% had excess weight; 1.3% and 18.9% had raised fasting blood glucose levels and triglycerides, respectively; 64.5% had low HDL cholesterol and 8.7% had blood pressure levels compatible with borderline high blood pressure. Thus, of the sample, 64.4% had at least one component for MetS; 11.6% had two, and 3.5% had three or more.CONCLUSION: a significant proportion of the population already has the components for metabolic syndrome, and this profile reinforces the importance of early diagnosis so as to reduce the risk of developing chronic comorbidities.

scholarly journals Whole-Body Cryotherapy Is an Effective Method of Reducing Abdominal Obesity in Menopausal Women with Metabolic Syndrome

2020 ◽  
Vol 9 (9) ◽  
pp. 2797
Author(s):  
Magdalena Wiecek ◽  
Jadwiga Szymura ◽  
Justyna Sproull ◽  
Zbigniew Szygula
Keyword(s):  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Abdominal Circumference ◽  
Whole Body ◽  
Moderate Physical Activity ◽  
Hip Circumference ◽  
Menopausal Women ◽  
Android Fat ◽  
Total Fat ◽  
Whole Body Cryotherapy

Abdominal obesity predominates in menopausal women (MW) and contributes to the development of metabolic syndrome (MetS). It is associated with increased mortality related to cardiovascular disease, diabetes and fatty liver disease. The effects of whole-body cryotherapy (WBC) on body composition and the blood concentration of irisin, interleukin-6 (IL-6) and C-reactive proteins (CRP) in MW with MetS and in healthy women (HW), were assessed. The study included 19 women with MetS (61.53 ± 3.99 y, BMI 30.09 ± 4.98 kg/m2) and 18 HW (60.28 ± 3.63 y, BMI 25.50 ± 2.37 kg/m2) who were subjected to 20 WBC treatments at −130 °C for 3 min daily. In both groups, body mass (BM), BMI, abdominal circumference, triceps skinfold, total fat mass and percentage of leg fat significantly decreased after 20 WBC sessions. Additionally, the percentage of total, trunk and android fat in the MetS group were significantly decreased after 20 WBC applications. Waist circumference (WC) and waist-to-height ratio (WHtR) significantly decreased in both groups, and in the HW group, hip circumference and abdominal skinfold also significantly decreased after 10 WBC and 20 WBC treatments. In both groups, the concentration of plasma irisin significantly increased after 1 WBC and 10 WBC exposures, while the concentration of IL-6 significantly increased only in MetS group after 10 WBC and 20 WBC, and were significantly higher than in HW. CRP concentrations were significantly higher in the MetS group than in HW before 1 WBC, after 1 WBC and 10 WBC sessions, but not after 20. In the MetS group, there were significant negative correlations between the change in irisin level and the changes in WC and BM, and between the level of irisin and the change in percentage of total fat, and significant negative correlations between the change in IL-6 level and changes in WC, waist-to-hip ratio and WHtR. Whole-body cryotherapy, assuming the application of 20 treatments in the series, reduces abdominal obesity in menopausal women indirectly through the secretion of irisin and IL-6, and can be used as adjunctive therapy in the treatment of metabolic syndrome. Our conclusion is limited to menopausal women with low–moderate physical activity for whom its level as well as diet were not changed during the treatment.

scholarly journals Effect of dental intervention on improvements in metabolic syndrome patients: a randomized controlled clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Midori Doke ◽  
Yuriko Komagamine ◽  
Manabu Kanazawa ◽  
Maiko Iwaki ◽  
Hiroyuki Suzuki ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Medical Information ◽  
Controlled Trial ◽  
Intervention Group ◽  
University Hospital ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Randomized Controlled ◽  
Dental Intervention ◽  
Water Rate

Abstract Background Metabolic syndrome (MetS), caused by the accumulation of visceral fat, is considered a major cause of cardiovascular disease. This randomized controlled trial aimed to clarify the effect of dental intervention, including prosthodontics and/or periodontal treatment, combined with dietary and exercise guidance on MetS. Methods In total, 112 patients who met the Japanese waist circumference criteria of MetS were recruited. The intervention group (ITG) received dental intervention along with dietary and exercise guidance, while the control group (CTG) received dietary and exercise guidance alone. Three outcome measurements were obtained before intervention (BL), 1 month after intervention (1M), and 3 months after intervention (3M). Results Body water rate (p = 0.043) was significantly higher in ITG than in CTG at 1M. Simultaneously, fasting blood sugar level (p = 0.098) tended to be lower in ITG than in CTG. Lean mass (p = 0.037) and muscle mass (p = 0.035) were significantly higher and body weight (p = 0.044) significantly lower in ITG than in CTG at 3M. Body mass index (p = 0.052) tended to be lower in ITG than in CTG. Conclusions Dental intervention combined with lifestyle guidance may improve anthropometric status and reduce the risk of MetS. Trial registration University Hospital Medical Information Network Center Unique UMIN000022753. https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000026176.

scholarly journals PERBAIKAN LINGKAR PERUT, TEKANAN DARAH, DAN BODY MASS INDEX WANITA SINDROM METABOLIK MENGGUNAKAN YOGURT SUSU KECAMBAH KACANG MERAH

2020 ◽  
Vol 4 (2) ◽  
pp. 173
Author(s):  
Hery Winarsi ◽  
Aisyah Tri Septiana ◽  
Avia Roselina
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Skim Milk ◽  
Kidney Bean ◽  
Abdominal Circumference ◽  
Before And After ◽  
Red Kidney Bean ◽  
Red Bean

This study aims to determine the effect of red kidney bean sprout milk yogurt (Rides-Yo) on abdominal circumference, blood pressure, and body mass index of metabolic syndrome women. Red kidney bean sprouts milk added with 10% sucrose and 10% skim milk pasteurized at 70 ° C for 10 minutes, then cooled to 45oC. Inoculated with lactic acid bacteria 2% of the total volume of red bean milk, incubated at 27-35oC for 24 hours. As many as 30 women, 40-65 years aged, central obesity, hypertension, and hyperlipidemia, live in the Baturraden subdistrict, Banyumas Regency, and are willing to sign informed consent. Subjects were randomly divided into 3 groups; the first group was given Rides-Yo; the second group was given a placebo; and group 3 took medicine from a doctor. A total of 200 mL/day of Rides-Yo or placebo was given to the subjects for 2 months. Before and after the intervention, subjects were measured for abdominal circumference, blood pressure, weight and height. There was a decrease in abdominal circumference (P=0,018), systole and diastolic blood pressure (P <0.038 and P=0,032), and BMI (P=0,039) in the group receiving Rides-Yo, compared to placebo and control groups. Thus, Rides-Yo is able to improve the health status of women with metabolic syndrome.  

scholarly journals Biochemical Profile Related to the Metabolic Syndrome in Patients Attended at a Basic Health Unit of Anápolis-GO

2017 ◽  
Vol 44 ◽  
pp. 1
Author(s):  
Deborah Rosa de Souza Albernaz ◽  
Ewerton Rodrigo Gassi ◽  
Kellen Christina Malheiros Borges
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Positive Result ◽  
Biochemical Parameters ◽  
Abdominal Circumference ◽  
Health Unit ◽  
Basic Health ◽  
The Metabolic Syndrome ◽  
Sindrome Metabolica

Abstract: The present study had as objective the monitoring of important biochemical parameters in the evaluation of health status / disease of individuals attended at a basic health unit of Anápolis - Goiás with the purpose of contributing in the prevention and treatment of a disease many times diagnosed late, the Metabolic Syndrome (MS). This is characterized by the correlation of risk factors, among them: obesity, atherogenic dyslipidemia, hypertension and hyperglycemia. Early identification of changes in the biochemical parameters that trigger MS allows a better treatment and prevention, mainly of cardiovascular diseases. The sample consisted of thirty volunteers, five men and twenty five women. Anthropometric, functional and biochemical parameters were evaluated for the determination of the risk factors. Abdominal circumference and body mass index (BMI) were used as anthropometric indicators and blood pressure was used as functional parameter. The biochemical indicators analyzed were: glycemic and lipid profile. The values found were compared with those indicated in the literature as reference values and the presence of MS was confirmed by the combination of the abdominal circumference parameter with two other risk factors, as recommended by the literature. Among the study participants, the results indicate that 3.3% did not present alterations in any of the parameters, 26.3% presented alterations in one or two of the evaluated parameters and 70% had a positive result for MS, being the abdominal circumference, pressure arterial and triglycerides parameters that had the highest frequency of change. Among the patients who had a positive result for MS, 62% had above ideal fasting glycemia values, 71.4% had triglyceride values above normal parameters, 81% had altered blood pressure and 85.7% had HDL-cholesterol levels below normal values. Based on the results found, it is concluded that the investigated population has a high rate of alterations in the biochemical and anthropometric parameters. Keywords: Metabolic syndrome. Biochemical parameters. Risk factors. Abdominal circumference. ---------------------------------------------------------------------------------- Perfil Bioquímico relacionado à Síndrome Metabólica em pacientes adultos ou idosos atendidos em uma Unidade Básica de Saúde de Anápolis-GO Resumo: O presente trabalho teve como objetivo o monitoramento de parâmetros bioquímicos importantes na avaliação do estado de saúde/doença de indivíduos adultos ou idosos atendidos em uma unidade básica de Saúde de Anápolis- Goiás com o intuito de contribuir na prevenção e tratamento de uma doença muitas vezes diagnosticada tardiamente, a Síndrome Metabólica (SM). Esta é caracterizada pela correlação de fatores de risco, dentre eles: obesidade, dislipidemia aterogênica, hipertensão arterial e hiperglicemia. Através da identificação precoce dessas alterações nos parâmetros bioquímicos que desencadeiam a SM é possível um melhor tratamento e prevenção principalmente de doenças cardiovasculares. Participaram da amostra da pesquisa 30 voluntários, sendo (5) homens e (25) mulheres. Para determinação dos fatores de risco foram avaliados parâmetros antropométricos, funcionais e bioquímicos. A circunferência de abdominal e o Índice de Massa Corporal (IMC) foram utilizados como indicadores antropométricos e a pressão arterial foi utilizada como parâmetro funcional. Os indicadores bioquímicos analisados foram: perfil glicêmico e lipídico. Os valores encontrados foram confrontados com os indicados na literatura como valores de referência e a presença da SM foi confirmada pela combinação do parâmetro de circunferência abdominal com mais dois outros fatores de risco, conforme recomenda a literatura. Os resultados indicaram que apenas um dos sujeitos avaliados não apresentou alteração em nenhum dos parâmetros, sendo o circunferência abdominal, pressão arterial e triglicerídeos os parâmetros que apresentaram maior frequência de alteração. Entre os participantes do estudo, 21 voluntários obtiveram resultado positivos para SM. Em relação aos parâmetros bioquímicos, a alteração nos níveis de colesterol foi acompanhada de valores elevados de triglicerídeos, bem como de alterações antropométricas e funcionais. Os indivíduos com níveis de triglicerídeos alterados, por sua vez, apresentaram também alterações antropométricas e funcionais. Com base nos resultados encontrados, conclui-se que a população investigada tem uma taxa elevada de alterações nos parâmetros bioquímicos e antropométricos. Palavras chave: Síndrome metabólica. Parâmetros bioquímicos. Fatores de risco. Circunferência abdominal. ---------------------------------------------------------------------------------- ■ Text in Portuguese

scholarly journals Frequency of metabolic syndrome in patients with newly diagnosed Type II Diabetes at DOW University Hospital, Karachi-Pakistan.

2021 ◽  
Vol 28 (11) ◽  
pp. 1546-1551
Author(s):  
Muhammad Umar Khan ◽  
Akhtar Ali Baloch ◽  
Muhammad Arsalan ◽  
Syed Muhammad Adnan
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Type Ii Diabetes ◽  
University Hospital ◽  
Diabetic Patients ◽  
Type Ii ◽  
Newly Diagnosed ◽  
Cross Sectional ◽  
The Mean

Objectives: To determine the prevalence of metabolic syndrome in patients with newly diagnosed type 2. Study Design: Descriptive Cross Sectional study. Setting: Dow University Hospital. Period: October 2018 to January 2019. Material & Methods: A total 342 patients prevalence of metabolic syndrome in patients with newly diagnosed type II diabetes at Dow University Hospital, Karachi, Pakistan. Data was collected through a questionnaire which is designed to record the age, gender, BMI, FBS, Waist circumference, blood pressure, HDL and triglyceride level of newly diagnosed of diabetic patients. Frequency and percentages were calculated for these variables. SPSS version 21 was used to analyze the overall results. Results: A total of 342 new diagnosed diabetic were included in this study. 189 (55.26%) were males and 153 (44.74%) were females. The mean + SD of age was 48.21±9.28 years. The mean + SD of FBS was about 192±43 mg/dl with ranges from 98 to 482 mg/dl. The mean + SD of Serum TG was about 243±152 mg/dl with ranges from 189 to 325 mg/dl. The mean + SD HDL was about 38.9±9.23 mg/dl with ranges from 12 to 102 mg/dl. The mean + SD of waist circumference was about 110.5±11.90 cm. The mean + SD systolic & diastolic blood pressure was about 150 + 8.23 & 98 + 11.28 respectively. The mean + SD of BMI was 29.23+ 11.23. Metabolic syndrome was diagnosed in 252 (73.68%) in newly diabetic patients. Conclusion: Metabolic syndromes were highly associated with newly diagnosed type II diabetes patients.

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