Pilot Testing A Breast Cancer Self-Management Support mHealth Application in Taiwan (Part 2): A Quantitative Study (Preprint)

2019 ◽  
Author(s):  
I-Ching Hou ◽  
Pei-Yu Tsai ◽  
Shan-Hsiang Shen ◽  
King-Jen Chang ◽  
Hao-Chih Tai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mobile Health ◽  
Rank Correlation ◽  
Ease Of Use ◽  
Self Management ◽  
Pilot Test ◽  
Management Support ◽  
Perceived Ease Of Use ◽  
Spearman’S Rank Correlation ◽  
Spearman’S Rank Correlation Coefficient

BACKGROUND Breast cancer has a high incidence rate among women in Taiwan and worldwide. Advanced surgery and medical therapies have improved survival rates. Today, smartphones are popular and can be used to develop ubiquitous technology for disease self-management and to maintain patients’ quality of life. In Taiwan, a mobile health self-management support app with eight main features was developed to address breast cancer women’s information needs based on prior research using a design thinking approach. OBJECTIVE The aim of this study was to pilot test Taiwan breast cancer women’s acceptance of the app. METHODS An instrument with confirmed reliability and validity based on the modified technology acceptance model for mobile services and aesthetics preference of interface icons was used. Women with breast cancer were recruited to participate in the pilot test workshop and then answer survey questionnaires. Descriptive statistics and Spearman’s rank correlation coefficient method was used to analyze the data. RESULTS A total of 45 women participated the study. They were mostly aged 41-50(40%, 18/45), bachelor’s degree or equivalent (54.4%, 29/45), married (66.7%, 30/45), stage II breast cancer (37.8%, 17/45), had completed treatment (55.6%, 25/45) and received surgical treatment (93.3%, 42/45). The highest mean scores of user acceptance factors rated on the 5-point Likert scale was perceived ease of use (4.14, SD=0.42), followed by actual use (4.12, SD=0.57), perceived value (4.07, SD=0.62), user satisfaction (4.01, SD=0.51), intention to use (3.89, SD=0.58), and the lowest mean score was trust (3.89, SD=0.58). The Spearman’s rank correlation coefficient indicated positive associations between each factor and statistically significant correlations (p value <0.05). Seven of eight interface feature icons in original app were favored over alternative icon options. CONCLUSIONS This study developed a smartphone app to predict Taiwan breast cancer women’s acceptance of mobile health technology for supporting disease self-management. The results suggest that patients positively accepted the app and would like it to be available in the future. However, data security and individual privacy protection features should be enhanced to increase users’ trust. In addition, the design of most interface icons was accepted by the participants which is consistent with their perceived ease of use of the app.

scholarly journals Exploring the Determinants of Mobile Health Adoption by Hospitals in China: Empirical Study (Preprint)

2019 ◽  
Author(s):  
Boumediene Ramdani ◽  
Binheng Duan ◽  
Ilhem Berrou
Keyword(s):  
Health Care ◽  
Mobile Health ◽  
Health Care Services ◽  
External Pressure ◽  
Ease Of Use ◽  
Public Hospitals ◽  
Management Support ◽  
Perceived Ease Of Use ◽  
Environmental Predictors ◽  
Hospital Size

BACKGROUND Although mobile health (mHealth) has the potential to transform health care by delivering better outcomes at a much lower cost than traditional health care services, little is known about mHealth adoption by hospitals. OBJECTIVE This study aims to explore the determinants of mHealth adoption by hospitals using the technology-organization-environment (TOE) framework. METHODS We conducted an interviewer-administered survey with 87 managers in Chinese public hospitals and analyzed the data using logistic regression. RESULTS The results of our survey indicate that perceived ease of use (β=.692; <i>P</i>&lt;.002), system security (β=.473; <i>P</i>&lt;.05), top management support (β=1.466; <i>P</i>&lt;.002), hospital size (β=1.069; <i>P</i>&lt;.004), and external pressure (β=.703; <i>P</i>&lt;.005) are significantly related to hospitals’ adoption of mHealth. However, information technology infrastructure (β=.574; <i>P</i>&lt;.02), system reliability (β=−1.291; <i>P</i>&lt;.01), and government policy (β=2.010; <i>P</i>&lt;.04) are significant but negatively related to hospitals’ adoption of mHealth. CONCLUSIONS We found that TOE model works in the context of mHealth adoption by hospitals. In addition to technological predictors, organizational and environmental predictors are critical for explaining mHealth adoption by Chinese hospitals.

scholarly journals The Development of a Mobile Health App for Breast Cancer Self-Management Support in Taiwan: Design Thinking Approach

10.2196/15780 ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. e15780 ◽  
Author(s):  
I-Ching Hou ◽  
Min-Fang Lan ◽  
Shan-Hsiang Shen ◽  
Pei Yu Tsai ◽  
King Jen Chang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mobile Health ◽  
Cultural Sensitivity ◽  
Information Needs ◽  
Design Thinking ◽  
Self Management ◽  
Management Support ◽  
User Centered Design ◽  
Individual Interviews ◽  
Taiwanese Women

Background Evidence has shown that breast cancer self-management support from mobile health (mHealth) apps can improve the quality of life of survivors. Although many breast cancer self-management support apps exist, few papers have documented the procedure for the development of a user-friendly app from the patient’s perspective. Objective This study aimed to investigate the information needs of Taiwanese women with breast cancer to inform the development of a self-management support mHealth app. Methods A 5-step design thinking approach, comprising empathy, define, ideate, prototype, and test steps, was used in the focus groups and individual interviews conducted to collect information on the requirements and expectations of Taiwanese women with breast cancer with respect to the app. A thematic analysis was used to identify information needs. Results A total of 8 major themes including treatment, physical activity, diet, emotional support, health records, social resources, experience sharing, and expert consultation were identified. Minor themes included the desire to use the app under professional supervision and a trustworthy app manager to ensure the credibility of information. Conclusions The strengths of the design thinking approach were user-centered design and cultural sensitivity. The results retrieved from each step contributed to the development of the app and reduction of the gap between end users and developers. An mHealth app that addresses these 8 main themes can facilitate disease self-management for Taiwanese women with breast cancer.

scholarly journals Motivational and personal differences of students with dissimilar degrees of self-realization in higher school education

2020 ◽  
Vol 48 (6) ◽  
pp. 345-357
Author(s):  
Andrey I. Shutenko ◽  
◽  
Elena N. Shutenko ◽  
Julia P. Derevyanko ◽  
Marina A. Kanishcheva ◽  
...  
Keyword(s):  
Research University ◽  
Rank Correlation ◽  
Personal Characteristics ◽  
University Education ◽  
Self Management ◽  
Learning Activity ◽  
Diagnostic Tools ◽  
Spearman’S Rank Correlation ◽  
Spearman’S Rank Correlation Coefficient ◽  
Student’S T

Effective training of competent specialists in a contemporary university requires the disclosure of personal abilities and internal potential of students who realize themselves as subjects of learning activity. The problem of studying the psychological factors of enhancing learning and self-realization of students in the educational space is of particular relevance. The hypothesis of the study was the assumption about the influence of motivational, personal-orientation and life-sense factors on the level of students' self-realization in university education. The study involved 224 students of the 4-5th courses from Belgorod National Research University and Belgorod State Technological University named after V.G. Shukhov. The author’s questionnaire for identifying the degree of students' self-realization in learning, as well as questionnaires and tests known in psychology for identification of motivational, personal and sense-purpose characteristics, served as diagnostic tools. The results were processed using cluster analysis, Student's t-test and Spearman's rank correlation coefficient. As a result it turned out that students with varying degrees of self-realization in education had differences in personal characteristics. Students with stable self-realization had higher scores for such motivational parameters as: attitude to learning (t = 7.056, p ≤ 0.001), self-expression need (t = 3.08, p = 0.003), satisfaction of achievements (t = 5.33, p ≤ 0.001). Meanwhile, students with low self-realization had an increased safety need (t = 2.26, p = 0.016). According to personal orientations and self-attitude, students with articulated self-realization were characterized by higher scores in terms of self-regard (t = 2.77, p = 0.007), self-management (t = 4.34, p ≤ 0.001), reflected self-attitude (t = 3.18, p = 0.002) and self-esteem (t = 3.02, p = 0.005). With regard to life-sense orientations, students with stable self-realization were distinguished by higher values of internal locus of control t = 4.50, p ≤ 0.001), life management (t = 4.07, p ≤ 0,001), life productivity (t = 3.84, p ≤ 0.001) and interesting eventful life (t = 3.80, p ≤ 0.001). Based on the correlation analysis, a number of positive relationships of self-realization markers in according to the questionnaire with personal characteristics of students were revealed. A positive connection was remarked between attitude to learning and following markers: the intention to work intensively in the classes (r = 0.52, p ≤ 0.01), recognizing of the usefulness of learning for oneself (r = 0.50, p ≤ 0.01), minimal learning frustration (r = 0.49, p ≤ 0.01). Satisfaction of knowledge correlated with markers of achieving a better self-knowledge (r = 0.49, p ≤ 0.01) and developing of personal abilities (r = 0.48, p ≤ 0.01). Self-management correlates with marker of achieving a deeper self-understanding (r = 0.47, p ≤ 0.01). Thus, the study made it possible to present the differentiated personal characteristics of students with different levels of self-realization in learning. The results can be useful for improving university practice in creating psychological and pedagogical conditions for a more complete students’ self-realization in the training process.

scholarly journals The Development of a Mobile Health App for Breast Cancer Self-Management Support in Taiwan: Design Thinking Approach (Preprint)

2019 ◽  
Author(s):  
I-Ching Hou ◽  
Min-Fang Lan ◽  
Shan-Hsiang Shen ◽  
Pei Yu Tsai ◽  
King Jen Chang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mobile Health ◽  
Cultural Sensitivity ◽  
Information Needs ◽  
Design Thinking ◽  
Self Management ◽  
Management Support ◽  
User Centered Design ◽  
Individual Interviews ◽  
Taiwanese Women

BACKGROUND Evidence has shown that breast cancer self-management support from mobile health (mHealth) apps can improve the quality of life of survivors. Although many breast cancer self-management support apps exist, few papers have documented the procedure for the development of a user-friendly app from the patient’s perspective. OBJECTIVE This study aimed to investigate the information needs of Taiwanese women with breast cancer to inform the development of a self-management support mHealth app. METHODS A 5-step design thinking approach, comprising empathy, define, ideate, prototype, and test steps, was used in the focus groups and individual interviews conducted to collect information on the requirements and expectations of Taiwanese women with breast cancer with respect to the app. A thematic analysis was used to identify information needs. RESULTS A total of 8 major themes including treatment, physical activity, diet, emotional support, health records, social resources, experience sharing, and expert consultation were identified. Minor themes included the desire to use the app under professional supervision and a trustworthy app manager to ensure the credibility of information. CONCLUSIONS The strengths of the design thinking approach were user-centered design and cultural sensitivity. The results retrieved from each step contributed to the development of the app and reduction of the gap between end users and developers. An mHealth app that addresses these 8 main themes can facilitate disease self-management for Taiwanese women with breast cancer.

scholarly journals Exploring the Determinants of Mobile Health Adoption by Hospitals in China: Empirical Study

10.2196/14795 ◽  
2020 ◽  
Vol 8 (7) ◽  
pp. e14795
Author(s):  
Boumediene Ramdani ◽  
Binheng Duan ◽  
Ilhem Berrou
Keyword(s):  
Health Care ◽  
Mobile Health ◽  
Health Care Services ◽  
External Pressure ◽  
Ease Of Use ◽  
Public Hospitals ◽  
Management Support ◽  
Perceived Ease Of Use ◽  
Environmental Predictors ◽  
Hospital Size

Background Although mobile health (mHealth) has the potential to transform health care by delivering better outcomes at a much lower cost than traditional health care services, little is known about mHealth adoption by hospitals. Objective This study aims to explore the determinants of mHealth adoption by hospitals using the technology-organization-environment (TOE) framework. Methods We conducted an interviewer-administered survey with 87 managers in Chinese public hospitals and analyzed the data using logistic regression. Results The results of our survey indicate that perceived ease of use (β=.692; P<.002), system security (β=.473; P<.05), top management support (β=1.466; P<.002), hospital size (β=1.069; P<.004), and external pressure (β=.703; P<.005) are significantly related to hospitals’ adoption of mHealth. However, information technology infrastructure (β=.574; P<.02), system reliability (β=−1.291; P<.01), and government policy (β=2.010; P<.04) are significant but negatively related to hospitals’ adoption of mHealth. Conclusions We found that TOE model works in the context of mHealth adoption by hospitals. In addition to technological predictors, organizational and environmental predictors are critical for explaining mHealth adoption by Chinese hospitals.

scholarly journals Deregulation of lncRNA HIST1H2AG-6 and AIM1-3 in peripheral blood mononuclear cells is associated with newly diagnosed type 2 diabetes

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Hui Jiang ◽  
Peian Lou ◽  
Xiaoluo Chen ◽  
Chenguang Wu ◽  
Shihe Shao
Keyword(s):  
Roc Curve ◽  
Multivariate Logistic Regression Analysis ◽  
Rank Correlation ◽  
Differentially Expressed ◽  
Healthy Controls ◽  
Biological Functions ◽  
Multivariate Logistic Regression ◽  
Spearman’S Rank Correlation ◽  
Spearman’S Rank Correlation Coefficient

Abstract Background Type 2 diabetes mellitus (T2DM) is mainly affected by genetic and environmental factors; however, the correlation of long noncoding RNAs (lncRNAs) with T2DM remains largely unknown. Methods Microarray analysis was performed to identify the differentially expressed lncRNAs and messenger RNAs (mRNAs) in patients with T2DM and healthy controls, and the expression of two candidate lncRNAs (lnc-HIST1H2AG-6 and lnc-AIM1-3) were further validated using quantitative real-time polymerase chain reaction (qRT-PCR). Spearman’s rank correlation coefficient was used to measure the degree of association between the two candidate lncRNAs and differentially expressed mRNAs. Furthermore, the KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway and GO (Gene Ontology) enrichment analysis were used to reveal the biological functions of the two candidate lncRNAs. Additionally, multivariate logistic regression analysis and receiver operating characteristic (ROC) curve analysis were performed. Results The microarray analysis revealed that there were 55 lncRNAs and 36 mRNAs differentially expressed in patients with T2DM compared with healthy controls. Notably, lnc-HIST1H2AG-6 was significantly upregulated and lnc-AIM1-3 was significantly downregulated in patients with T2DM, which was validated in a large-scale qRT-PCR examination (90 controls and 100 patients with T2DM). Spearman’s rank correlation coefficient revealed that both lncRNAs were correlated with 36 differentially expressed mRNAs. Furthermore, functional enrichment (KEGG and GO) analysis demonstrated that the two lncRNA-related mRNAs might be involved in multiple biological functions, including cell programmed death, negative regulation of insulin receptor signal, and starch and sucrose metabolism. Multivariate logistic regression analysis revealed that lnc-HIST1H2AG-6 and lnc-AIM1-3 were significantly correlated with T2DM (OR = 5.791 and 0.071, respectively, both P = 0.000). Furthermore, the ROC curve showed that the expression of lnc-HIST1H2AG-6 and lnc-AIM1-3 might be used to differentiate patients with T2DM from healthy controls (area under the ROC curve = 0.664 and 0.769, respectively). Conclusion The profiles of lncRNA and mRNA were significantly changed in patients with T2DM. The expression levels of lnc-HIST1H2AG-6 and lnc-AIM1-3 genes were significantly correlated with some features of T2DM, which may be used to distinguish patients with T2DM from healthy controls and may serve as potential novel biomarkers for diagnosis in the future.

scholarly journals Association between Endoscopic Milk-White Mucosa, Epithelial Intracellular Lipid Droplets, and Histological Grade of Superficial Non-Ampullary Duodenal Epithelial Tumors

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 769
Author(s):  
Yuko Hara ◽  
Kenichi Goda ◽  
Shinichi Hirooka ◽  
Takehiro Mitsuishi ◽  
Masahiro Ikegami ◽  
...  
Keyword(s):  
Lipid Droplets ◽  
Histological Grade ◽  
Rank Correlation ◽  
Intraepithelial Neoplasia ◽  
Low Grade ◽  
Intracellular Lipid ◽  
En Bloc ◽  
Spearman’S Rank Correlation ◽  
Spearman’S Rank Correlation Coefficient ◽  
Positive Rate

We previously reported that superficial non-ampullary duodenal tumors (SNADETs) commonly had a whitish mucosal surface, named milk-white mucosa (MWM). The aim of this study was to evaluate the association of MWM with epithelial intracellular lipid droplets (immunohistochemically stained by adipose differentiation-related protein (ADRP)) and histological tumor grades. We reviewed endoscopic images and the histopathology of SNADETs resected en bloc endoscopically. We analyzed the correlation between the positive rates of endoscopic MWM in preoperative endoscopy and resected specimens, and ADRP-positive rates in the resected specimens. Associations between the MWM-positive rates and tumor grades, high-grade intraepithelial neoplasia (HGIN)/intramucosal carcinoma (IC), and low-grade intraepithelial neoplasia (LGIN) were analyzed. All the 92 SNADETs analyzed were <20 mm and histologically classified into 39 HGIN/IC and 53 LGIN. Spearman’s rank correlation coefficient showed a significant correlation between MWM-positive and ADRP-positive rates (p < 0.001). MWM-positive rates were significantly lower in the HGIN/IC than in the LGIN in preoperative endoscopy (p < 0.001) and resected specimens (p = 0.02). Our results suggest that endoscopic MWM is closely associated with epithelial intracellular lipid droplets and that the MWM-positive rate may be a predictor of histological grade in small SNADETs.

scholarly journals Correlation between nasopharyngoscopy and cephalometry in the diagnosis of hyperplasia of the pharyngeal tonsils

2012 ◽  
Vol 16 (02) ◽  
pp. 209-216 ◽  
Author(s):  
Luana Berwig ◽  
Ana da Silva ◽  
Eliane Corrêa ◽  
Eliane Serpa ◽  
Rodrigo Ritzel
Keyword(s):  
Quantitative Study ◽  
Fiber Optic ◽  
Rank Correlation ◽  
Accurate Diagnosis ◽  
Cross Sectional ◽  
Significance Level ◽  
Spearman’S Rank Correlation ◽  
Spearman’S Rank Correlation Coefficient ◽  
Tonsil Hyperplasia ◽  
Pharyngeal Tonsil

Summary Introduction: Hyperplasia of the pharyngeal tonsil is one of the main causes of mouth breathing, and accurate diagnosis of this alteration is important for proper therapeutic planning. Therefore, studies have been conducted in order to provide information regarding the procedures that can be used for the diagnosis of pharyngeal obstruction. Objective: To verify the correlation between nasopharyngoscopy and cephalometric examinations in the diagnosis of pharyngeal tonsil hyperplasia. Method: This was a cross-sectional, clinical, experimental, and quantitative study. Fifty-five children took part in this study, 30 girls and 25 boys, aged between 7 and 11 years. The children underwent nasofibropharyngoscopic and cephalometric evaluation to determine the grade of nasopharyngeal obstruction. The Spearman's rank correlation coefficient at the 5% significance level was used to verify the correlation between these exams. Results: In the nasopharyngoscopy evaluation, most children showed grade 2 and 3 hyperplasia of the pharyngeal tonsil, which was followed by grade 1. In the cephalometry assessment, most children showed grade 1 hyperplasia of the pharyngeal tonsil, which was followed by grade 2. A statistically significant regular positive correlation was observed between the exams. Conclusion: It was concluded that the evaluation of the pharyngeal tonsil hyperplasia could be carried out by fiber optic nasopharyngoscopy and cephalometry, as these examinations were regularly correlated. However, it was found that cephalometry tended to underestimate the size of the pharyngeal tonsil relative to nasopharyngoscopy.

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