scholarly journals A Practical Do-It-Yourself Recruitment Framework for Concurrent eHealth Clinical Trials: Simple Architecture (Part 1) (Preprint)

2018 ◽  
Author(s):  
Hannah L Palac ◽  
Nameyeh Alam ◽  
Susan M Kaiser ◽  
Jody D Ciolino ◽  
Emily G Lattie ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Academic Research ◽  
Task Assignment ◽  
Management Tools ◽  
Successful Recruitment ◽  
Referral Management ◽  
Study Staff ◽  
Do It Yourself ◽  
Participant Flow ◽  
Group Interviews

BACKGROUND The ability to identify, screen, and enroll potential research participants in an efficient and timely manner is crucial to the success of clinical trials. In the age of the internet, researchers can be confronted with large numbers of people contacting the program, overwhelming study staff and frustrating potential participants. OBJECTIVE This paper describes a “do-it-yourself” recruitment support framework (DIY-RSF) that uses tools readily available in many academic research settings to support remote participant recruitment, prescreening, enrollment, and management across multiple concurrent eHealth clinical trials. METHODS This work was conducted in an academic research center focused on developing and evaluating behavioral intervention technologies. A needs assessment consisting of unstructured individual and group interviews was conducted to identify barriers to recruitment and important features for the new system. RESULTS We describe a practical and adaptable recruitment management architecture that used readily available software, such as REDCap (Research Electronic Data Capture) and standard statistical software (eg, SAS, R), to create an automated recruitment framework that supported prescreening potential participants, consent to join a research registry, triaging for management of multiple trials, capture of eligibility information for each phase of a recruitment pipeline, and staff management tools including monitoring of participant flow and task assignment/reassignment features. The DIY-RSF was launched in July 2015. As of July 2017, the DIY-RSF has supported the successful recruitment efforts for eight trials, producing 14,557 participant records in the referral tracking database and 5337 participants in the center research registry. The DIY-RSF has allowed for more efficient use of staff time and more rapid processing of potential applicants. CONCLUSIONS Using tools already supported at many academic institutions, we describe the architecture and utilization of an adaptable referral management framework to support recruitment for multiple concurrent clinical trials. The DIY-RSF can serve as a guide for leveraging common technologies to improve clinical trial recruitment procedures.

Pesquisas sobre Currículos e Culturas: tensões, movimentos e criações

2020 ◽  
Author(s):  
Maria Patrícia Silva
Keyword(s):  
Health Care ◽  
Research Group ◽  
Training Programs ◽  
Academic Research ◽  
Art Music ◽  
The Other ◽  
Educational Policies ◽  
Cultural Spaces ◽  
Teacher Training Programs ◽  
Do It Yourself

The book Research on Curricula and Cultures: tensions, movements and creations, organized by Marlucy Alves Paraíso and Maria Patrícia Silva, it consists of 17 chapters, one of which is an interesting work by a Canadian scholar who investigates state anti-feminism. The other chapters bring results from 16 researches developed by researchers from the Study and Research Group on Curricula and Cultures (GECC), created and coordinated by Marlucy Alves Paraíso, which has researchers from several Brazilian universities and states. The articles in the book combine the post-critical perspectives used to investigate curricula and cultures in their different nuances, addressing silences, power relations, modes of subjectivation and the movements that prevent their fixity. The book brings research results that discuss the possibilities of creating possibilities at school and in other cultural spaces that also have curricula and develop pedagogies, such as: cyberspace, city, health care programs, teacher training programs, educational policies, etc. In addition, curricula are investigated with emphasis on different practices and aspects: childhood, art, music, dance, gender, sexuality, ethnicity, corporality, politics, with research that also innovates methodologically when operating with openings, experiments, do-it-yourself and compositions in different ways. to research curricula without rigidity, although with the necessary rigor in academic research. O livro reconhece de diferentes modos as possibilidades de conexões entre currículos e culturas, e mostra movimentos capazes de operar transgressões apostando em uma cultura porvir.

Abstract 56: Acute Stroke Reperfusion Treatment Rates at NIH StrokeNET Hospitals

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Opeolu Adeoye ◽  
Dawn Kleindorfer
Keyword(s):  
Clinical Trials ◽  
High Volume ◽  
The United States ◽  
Primary Diagnosis ◽  
Categorical Variables ◽  
Phase 3 ◽  
Chi Square ◽  
Successful Recruitment ◽  
Chi Square Test ◽  
Reperfusion Phase

Background: In 2013, the NIH Stroke Trials Network (StrokeNET) was established to maximize efficiencies in stroke clinical trials. Successful recruitment in future trials was required for participating sites. A high volume of cases treated is a surrogate for the potential to recruit. Among Medicare-eligible acute ischemic stroke (AIS) cases, we estimated the IV rt-PA and endovascular embolectomy treatment rates at StrokeNET Regional Coordinating Centers and their partner hospitals compared with non-StrokeNET hospitals in the United States (US). Methods: We used demographics and IV rt-PA and embolectomy rates in the 2013 Medicare Provider and Analysis Review (MEDPAR) dataset. ICD-9 codes 433.xx, 434.xx and 436 identified AIS cases. ICD-9 code 99.10 defined rt-PA treatment and ICD-9 code 39.74 defined embolectomy. Demographics and treatment rates at StrokeNET and non-StrokeNET sites were compared using t-test for proportions and Chi-square test for categorical variables as appropriate. Results: Of 386,157 AIS primary diagnosis discharges, 5.1% received IV rt-PA and 0.8% had embolectomy (Table). By June 6, 2014, StrokeNET comprised 247 acute care hospitals that discharged 48,946 (13%) out of 386,157 AIS cases. rt-PA (7.4% vs 4.8%) and embolectomy (1.9% vs 0.6%) treatment rates were higher at StrokeNET hospitals. In 2013, 36% of StrokeNET hospitals treated more than 20 AIS cases with rt-PA or embolectomy compared with 6% of non-StrokeNET hospitals (P<0.0001).Conclusions StrokeNET hospitals treat more AIS cases with acute reperfusion therapies. Thus, StrokeNET could successfully recruit in acute reperfusion clinical trials depending on study size, capture of eligible patients and the number of competing trials. We likely underestimated treatment rates due to not accounting for drip-and-ship and non-Medicare cases. To further enhance enrollments in large acute reperfusion phase 3 trials, partnership with high volume non-StrokeNET hospitals may be warranted.

scholarly journals Vegetarian food recommendation in the traditional Islamic teachings to increase the fertility of men

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Reza Dehghani Bidgoli
Keyword(s):  
Clinical Trials ◽  
Male Infertility ◽  
Seminal Fluid ◽  
Medical Science ◽  
Academic Research ◽  
Narrative Texts ◽  
Vegetable Food ◽  
New Knowledge ◽  
Effective Drugs

Abstract About half of the infertilities are due to men’s problems. In medicine, there are valuable treasures that confirm the effectiveness of some of them today and they have been approved for the treatment of diseases. The purpose of this paper is to investigate the drug’s advice in increasing the fertility of men in Muslim narrative texts and compare it with new knowledge of humanity in medicine. For this purpose, we searched the fertility, men, and vegetable food keywords in the database and valid Islamic books and presented them in this article. Also, the results of academic research have also been pointed out to confirm these religious teachings. Some of the issues in traditional Islamic teachings that have been expressed centuries ago have been confirmed by modern medical science and have been the basis of making effective drugs for treating male infertility. Some of them also need further research. According to the emphasis of available Islamic traditional medicine from the infallible on the efficacy of the vegetable food in improving the quality of the seminal fluid and also confirming the usefulness in clinical trials, these plants can be useful in increasing fertility.

scholarly journals Strategies for Successful Recruitment of Pregnant Patients Into Clinical Trials

2017 ◽  
Vol 129 (3) ◽  
pp. 554-559 ◽  
Author(s):  
Elizabeth F. Sutton ◽  
Loren E. Cain ◽  
Porsha M. Vallo ◽  
Leanne M. Redman
Keyword(s):  
Clinical Trials ◽  
Successful Recruitment

scholarly journals Nasjonale prøver – hemmende styringsverktøy eller lokale redskap for praksisutvikling?

2018 ◽  
Vol 12 (4) ◽  
pp. 3
Author(s):  
Ole Petter Vestheim
Keyword(s):  
Standardized Tests ◽  
Theoretical Perspective ◽  
Management Tools ◽  
Practice Architectures ◽  
Group Interviews ◽  
National Tests ◽  
Practice Development ◽  
Shed Light ◽  
Development Practice ◽  
Over Time

Artikkelen bygger på empiri fra en studie som hadde til hensikt å undersøke hva som kjennetegner praksis(er) på skoler som over tid har oppnådd gode resul¬tater på nasjonale prøver. Studiens hensikt var å utvikle forskningsbasert kunnskap om forhold som er av betydning for å lykkes på de nasjonale prøvene og avdekke hvilken plass prøvene hadde i skolenes praksis. Data ble innhentet med bruk av kvalitative singel- og gruppeintervjuer med rektorer og lærere fra sju skoler. Det teoretiske perspektivet og funnene i studien bidrar til å kaste lys over hvordan nasjonale prøver, som inngår i skolenes praksisarkitekturer, bidrar til praksisutvikling.Nøkkelord: standardiserte prøver, nasjonale prøver, skoleutvikling, praksis, praksisarkitekturerNational tests – inhibitory management tools or local tools for practice development?AbstractThe article is based on empirical evidence from a study that intended to investi¬gate what characterizes practice(s) in schools that have achieved good results in national tests over time. The purpose of the study was to develop research-based knowledge about conditions that are important for the success in the national tests and to reveal the place that the tests had in the practice of the schools. Data was obtained using qualitative single and group interviews with principals and teachers from seven schools. The theoretical perspective and the findings in the study help to shed light on how national tests, which are part of the schools’ practice architectures, contribute to practice development.Keywords: standardized tests, national tests, school development, practice, practice architectures

scholarly journals Analysis of costs and strategies for using academic research in a private dental college to develop commercially viable products

2020 ◽  
Author(s):  
Rampalli Viswa Chandra ◽  
Devaraju Rama Raju
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Product Development ◽  
Negative Impact ◽  
Academic Research ◽  
Research Projects ◽  
Trial Duration ◽  
Cycle Times ◽  
Surgical Devices

ABSTRACTBackground & objectivesThe study had two aims. 1) Analysis of research projects done in our institution from 2014-2019 to identify products with a potential for commercialization and 2) To understand the effect of product-development variables on research projects to improve the quality of future commercialization-oriented trials.Methods338 clinical trials were grouped into 188 projects under the headings irrigants, diagnostic devices, surgical devices, biomaterials and gels. Trials per project, capital, material costs, labour and the cycle times per trial were calculated. To understand the effect these variables, five hypotheses were generated to test whether greater number of trials, successes, higher capital, more investigators per trial and a longer trial duration will result in a product worthy of commercialization.Results22 projects had products with a potential for commercialization. Except labour and cycle time (p>0.05), all variables showed significant differences across all projects. Three products were identified as having potential for actual commercialization. It was observed that greater number of trials (χ2=4.6793; p=0.030528) and successes (χ2=20.8134; p<0.00001) in a project along with a higher capital (χ2=12.2662; p=0.000461) will generate a product worthy of commercialization.Interpretation & conclusionsThe results seem to suggest that in trials for commercialization, emphasis must be placed on implementing multiple, well-designed clinical trials on a device or product to successfully identify whether it is commercialization-worthy or not. Due attention must be given to the financial aspects of the projects as deficiencies may result in negative impact on the flow and outcomes of a clinical trial.

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