scholarly journals Cardiovascular Health Effects of Internet-Based Encouragements to Do Daily Workplace Stair-Walks: Randomized Controlled Trial

2013 ◽  
Vol 15 (6) ◽  
pp. e127 ◽  
Author(s):  
Lars Louis Andersen ◽  
Emil Sundstrup ◽  
Marianne Boysen ◽  
Markus Due Jakobsen ◽  
Ole Steen Mortensen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Health Effects ◽  
Cardiovascular Health ◽  
Controlled Trial ◽  
Randomized Controlled

scholarly journals A randomized, controlled trial comparing skin health effects and comfort of two adult incontinence protective underwear

2016 ◽  
Vol 23 (2) ◽  
pp. 202-211 ◽  
Author(s):  
M. M. Trowbridge ◽  
B. Wang ◽  
D. Gutshall ◽  
C. A. Rodenberg ◽  
M. A. Farage
Keyword(s):  
Randomized Controlled Trial ◽  
Health Effects ◽  
Controlled Trial ◽  
Randomized Controlled

scholarly journals Health Effects of Written Emotional Disclosure in Adolescents with Asthma: A Randomized, Controlled Trial

2005 ◽  
Vol 31 (6) ◽  
pp. 557-568 ◽  
Author(s):  
Lori J. Warner ◽  
Mark A. Lumley ◽  
Rita J. Casey ◽  
Wayne Pierantoni ◽  
Reina Salazar ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Health Effects ◽  
Controlled Trial ◽  
Emotional Disclosure ◽  
Written Emotional Disclosure ◽  
Randomized Controlled

Abstract MP72: Feasibility, Safety and Acceptability of Soy-Based Diet for Pregnant Women: Preliminary Results From a Pilot Randomized Controlled Trial

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Ling Shi ◽  
Vidya Iyer ◽  
Errol Norwitz ◽  
Tiffany A Moore Simas ◽  
Nirupa Matthan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Adverse Events ◽  
Pregnant Women ◽  
Health Effects ◽  
Cardiometabolic Risk ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial ◽  
Whole Foods

Introduction: Previous evidence suggests that soy containing foods may have beneficial effects on lipid and glycemic metabolism due to their biologically active components, including soy protein and isoflavones. Pregnancy is associated with changes in glucose and lipid metabolism, partially attributable to elevated estrogen concentrations. We have previously reported a significant, inverse association between urinary excretion of isoflavones and cardiometabolic risk markers in pregnant women, using data from the National Health and Nutrition Examination Survey (NHANES). Further studies are needed to determine the cardiometabolic health effects of soy intake in pregnant women. Hypothesis: We hypothesize that consumption of soy-based whole foods is safe and acceptable for pregnant women and has beneficial cardiometabolic health effects. Methods: A pilot randomized controlled trial (RCT) was conducted in 30 pregnant women who received counseling to consume either a high-soy or low-soy foods containing diet. Assessments (physical and anthropometric measurements, food frequency questionnaires, fasting blood samples) were conducted at 14 and 28 weeks of pregnancy, and 6 weeks’ postpartum. Monthly follow-up calls were conducted by research team coordinator to assess safety and encourage adherence. Results: Both the high-soy and low-soy groups demonstrated high adherence (80-90%), defined as consuming soy foods ≥ 15 days in the past four weeks for high-soy group and ≤ 5 days for low-soy group. Five subjects in the high-soy group reported adverse events (nausea, vomiting, diarrhea, itchy mouth); all were transient and resolved without sequelae. No adverse events were reported in the low-soy group. Skinfold thickness decreased (-4.8 mm) in the high-soy group and increased (+3.6 mm) in the low-soy group (p=0.04). There was a trend towards lower BMI in the high-soy compared to low-soy group at 28 weeks (+1.4 vs. +3.6 kg/m 2 , respectively, p=0.15) and postpartum (-1.2 vs. +0.6 kg/m 2 , respectively, p=0.14). This decrease in BMI was predominantly a loss of body fat and not lean mass. There were no significant differences between groups in fasting glucose, HDL-C, LDL-C, TG, or VLDL concentrations. Conclusions: In conclusion, results from this pilot RCT support the acceptability and safety of consuming soy-based whole foods during pregnancy. A larger-scale RCT is needed to further elucidate the effects of soy-based foods on cardiometabolic risk factors during pregnancy, as well as the transgenerational effects on their offspring.

scholarly journals Enhancing the Cardiovascular Protective Effects of a Healthy Dietary Pattern with Wolfberry (Lycium barbarum): A Randomized Controlled Trial

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 82-82
Author(s):  
Darel Wee Kiat Toh ◽  
Xuejuan Xia ◽  
Jasmine Hui Min Low ◽  
Clarinda Sutanto ◽  
Wan Yee Lee ◽  
...  
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Dietary Pattern ◽  
Cardiovascular Health ◽  
Controlled Trial ◽  
Protective Effects ◽  
Lycium Barbarum ◽  
Endothelin 1 ◽  
Randomized Controlled ◽  
Healthy Dietary Pattern

Abstract Objectives The study aimed to investigate the impact of wolfberry (Lycium barbarum) consumption as part of a healthy dietary pattern on cardiovascular health in Singaporean middle-aged and older adults. It was hypothesized that the consumption of wolfberry could further enhance the cardiovascular protective effects of a healthy dietary pattern. Methods This was a 16 week, parallel design, randomized controlled trial where 40 Singaporean men and women (aged 50 to 64 years) received dietary counselling to follow a healthy dietary pattern either with or without 15 g/day of dried whole wolfberry, cooked and consumed as part of their meals. Blood pressure, serum lipid-lipoprotein concentrations and dietary compliance using 3-day food records were monitored every 4 weeks. Further evaluation of cardiovascular disease (CVD) biomarkers, broadly classified as serological (total nitrate/nitrite, endothelin-1, intercellular adhesion molecule-1, angiopoietin-1, angiopoietin-2 and von-Willebrand factor), structural (carotid intima-media thickness using B-mode ultrasonography) and functional (flow-mediated dilation using B-mode ultrasonography and circulating endothelial progenitor cells (CD34+/KDR+) by fluorescence-activated cell sorting) were analyzed before and after intervention. Results Adherence to a healthy dietary pattern contributed to a time dependent effect on both the plasma total nitrate/nitrite (P < 0.01) and plasma endothelin-1 (P < 0.005) which were raised and lowered respectively at week 16. However, changes were significant only in the wolfberry group (total nitrate/nitrite: 15.9 ± 1.8 to 19.4 ± 2.2 μmol/L, P < 0.05; endothelin-1: 1.31 ± 0.12 to 1.11 ± 0.10 ng/L, P < 0.01) and not in the control group. Moreover, a significant increase in serum high density lipoprotein (HDL) cholesterol was also detected solely in the wolfberry group (1.56 ± 0.10 to 1.65 ± 0.10 mmol/L, P < 0.05). The other serological, structural and functional biomarkers of cardiovascular health showed no observable change after the intervention. Conclusions Incorporating wolfberry to your daily meals may augment the cardiovascular protective benefits of a healthy dietary pattern by improving the regulation of vascular tone and plasma lipid-lipoprotein profile in Singaporean middle-aged and older adults. Funding Sources Ministry of Education, Singapore.

Effects of dry-cured ham rich in bioactive peptides on cardiovascular health: A randomized controlled trial

2017 ◽  
Vol 38 ◽  
pp. 160-167 ◽  
Author(s):  
Silvia Montoro-García ◽  
María Pilar Zafrilla-Rentero ◽  
Francisco Miguel Celdrán-de Haro ◽  
Juan José Piñero-de Armas ◽  
Fidel Toldrá ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cardiovascular Health ◽  
Bioactive Peptides ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Dry Cured Ham

scholarly journals Research protocol for a randomized controlled trial of the health effects of volunteering for seniors

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Simone Pettigrew ◽  
Michelle Jongenelis ◽  
Robert U Newton ◽  
Jeni Warburton ◽  
Ben Jackson
Keyword(s):  
Randomized Controlled Trial ◽  
Health Effects ◽  
Controlled Trial ◽  
Research Protocol ◽  
Randomized Controlled
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