Effects of dry-cured ham rich in bioactive peptides on cardiovascular health: A randomized controlled trial

2017 ◽  
Vol 38 ◽  
pp. 160-167 ◽  
Author(s):  
Silvia Montoro-García ◽  
María Pilar Zafrilla-Rentero ◽  
Francisco Miguel Celdrán-de Haro ◽  
Juan José Piñero-de Armas ◽  
Fidel Toldrá ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cardiovascular Health ◽  
Bioactive Peptides ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Dry Cured Ham

scholarly journals Enhancing the Cardiovascular Protective Effects of a Healthy Dietary Pattern with Wolfberry (Lycium barbarum): A Randomized Controlled Trial

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 82-82
Author(s):  
Darel Wee Kiat Toh ◽  
Xuejuan Xia ◽  
Jasmine Hui Min Low ◽  
Clarinda Sutanto ◽  
Wan Yee Lee ◽  
...  
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Dietary Pattern ◽  
Cardiovascular Health ◽  
Controlled Trial ◽  
Protective Effects ◽  
Lycium Barbarum ◽  
Endothelin 1 ◽  
Randomized Controlled ◽  
Healthy Dietary Pattern

Abstract Objectives The study aimed to investigate the impact of wolfberry (Lycium barbarum) consumption as part of a healthy dietary pattern on cardiovascular health in Singaporean middle-aged and older adults. It was hypothesized that the consumption of wolfberry could further enhance the cardiovascular protective effects of a healthy dietary pattern. Methods This was a 16 week, parallel design, randomized controlled trial where 40 Singaporean men and women (aged 50 to 64 years) received dietary counselling to follow a healthy dietary pattern either with or without 15 g/day of dried whole wolfberry, cooked and consumed as part of their meals. Blood pressure, serum lipid-lipoprotein concentrations and dietary compliance using 3-day food records were monitored every 4 weeks. Further evaluation of cardiovascular disease (CVD) biomarkers, broadly classified as serological (total nitrate/nitrite, endothelin-1, intercellular adhesion molecule-1, angiopoietin-1, angiopoietin-2 and von-Willebrand factor), structural (carotid intima-media thickness using B-mode ultrasonography) and functional (flow-mediated dilation using B-mode ultrasonography and circulating endothelial progenitor cells (CD34+/KDR+) by fluorescence-activated cell sorting) were analyzed before and after intervention. Results Adherence to a healthy dietary pattern contributed to a time dependent effect on both the plasma total nitrate/nitrite (P < 0.01) and plasma endothelin-1 (P < 0.005) which were raised and lowered respectively at week 16. However, changes were significant only in the wolfberry group (total nitrate/nitrite: 15.9 ± 1.8 to 19.4 ± 2.2 μmol/L, P < 0.05; endothelin-1: 1.31 ± 0.12 to 1.11 ± 0.10 ng/L, P < 0.01) and not in the control group. Moreover, a significant increase in serum high density lipoprotein (HDL) cholesterol was also detected solely in the wolfberry group (1.56 ± 0.10 to 1.65 ± 0.10 mmol/L, P < 0.05). The other serological, structural and functional biomarkers of cardiovascular health showed no observable change after the intervention. Conclusions Incorporating wolfberry to your daily meals may augment the cardiovascular protective benefits of a healthy dietary pattern by improving the regulation of vascular tone and plasma lipid-lipoprotein profile in Singaporean middle-aged and older adults. Funding Sources Ministry of Education, Singapore.

scholarly journals The Healing Hearts Together Randomized Controlled Trial and the COVID-19 Pandemic: A Tutorial for Transitioning From an In-Person to a Web-Based Intervention

10.2196/25502 ◽  
2021 ◽  
Vol 23 (4) ◽  
pp. e25502
Author(s):  
Kathleen Lalande ◽  
Paul S Greenman ◽  
Karen Bouchard ◽  
Susan M Johnson ◽  
Heather Tulloch
Keyword(s):  
Randomized Controlled Trial ◽  
Cardiovascular Health ◽  
Transition Planning ◽  
Controlled Trial ◽  
Web Based ◽  
Participant Recruitment ◽  
Randomized Controlled ◽  
Health Quality ◽  
Step Transition

Supportive couple relationships are associated with reduced risk of chronic illness development, such as cardiovascular disease, as well as improved secondary prevention. Healing Hearts Together (HHT) is an 8-week couples-based intervention designed to improve relationship quality, mental health, quality of life, and cardiovascular health among couples in which one partner has experienced a cardiac event. A randomized controlled trial began in October 2019 to test the efficacy of the in-person, group-based HHT program as compared to usual care. In March of 2020, all recruitment, assessments, and interventions halted due to the COVID-19 pandemic. Guided by optimal virtual care principles, as well as by Hom and colleagues’ four-stage framework—consultation, adaptation, pilot-testing, and test launch—this paper is a tutorial for the step-by-step transition planning and implementation of a clinical research intervention from an in-person to a web-based format, using the HHT program as an example. Clinical and research considerations are reviewed, including (1) privacy, (2) therapeutic aspects of the intervention, (3) group cohesion, (4) research ethics, (5) participant recruitment, (6) assessment measures, (7) data collection, and (8) data analyses. This tutorial can assist clinical researchers in transitioning their research programs to a web-based format during the pandemic and beyond.

scholarly journals Kettlebell training for musculoskeletal and cardiovascular health: a randomized controlled trial

2010 ◽  
Vol 37 (3) ◽  
pp. 196-203 ◽  
Author(s):  
Kenneth Jay ◽  
Dennis Frisch ◽  
Klaus Hansen ◽  
Mette K Zebis ◽  
Christoffer H ­ Andersen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cardiovascular Health ◽  
Controlled Trial ◽  
Randomized Controlled
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