scholarly journals Effects of Unfiltered Cigarettes on Smoking Behavior and Toxicant Exposure: Protocol for a Randomized Crossover Clinical Trial

10.2196/19603 ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. e19603
Author(s):  
Eyal Oren ◽  
Kim Pulvers ◽  
Devan R Romero ◽  
Casey Barber ◽  
Erika Carter ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Scientific Evidence ◽  
Research Question ◽  
Smoking Behavior ◽  
Baseline Period ◽  
Self Report ◽  
Future Research ◽  
Institutional Review Boards ◽  
Single Use ◽  
The Impact

Background Plastic filters on cigarette butts are a widespread source of nonbiodegradable, toxic environmental waste. State and local legislation to ban the sale of single-use cigarettes may be considered to prevent this waste, but scientific evidence on the impact of switching smokers to unfiltered cigarettes on smoking behavior and toxicant exposures is needed to inform this policy. We have designed an open-label, randomized, 9-week, crossover clinical trial of adult filtered-cigarette smokers who switch to unfiltered cigarettes. Objective Our objective is to understand the impact of switching smokers of filtered cigarettes to unfiltered cigarettes on smoking behavior and toxic exposures. Methods This trial involves a 1-week baseline period; a 2-week period of smoking filtered or unfiltered cigarettes, where groups are randomly assigned; a 3-week washout period; another 1-week baseline period; and a 2-week crossover period of smoking the opposite condition (ie, filtered or unfiltered cigarettes) for a sufficient sample size of 40 participants. We will determine changes in (1) observed topography (ie, puff count, interpuff interval, and puff volume) and cigarettes smoked per day, via butt counts and self-report, (2) expired carbon monoxide and excretion of urinary cotinine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and volatile organic compounds, and (3) participants’ knowledge and attitudes toward unfiltered cigarettes, satisfaction with smoking, and intention to quit if they were not able to smoke filtered cigarettes. Results This study was funded in June 2018 and approved by the relevant Institutional Review Boards in July 2018. This study has enrolled 37 participants as of October 2020. Data analysis is currently underway, and trial results are expected to be published in spring 2021. Conclusions This pilot proof-of-principle study will inform the design of a larger, future research project that can provide robust scientific evidence on our research question. Such a large study could inform possible state or local legislation to ban the sale of single-use filtered cigarettes in order to mitigate the environmental impact of discarded single-use plastic filters. Trial Registration ClinicalTrials.gov NCT03749876; https://clinicaltrials.gov/ct2/show/NCT03749876 International Registered Report Identifier (IRRID) DERR1-10.2196/19603

scholarly journals Effects of Unfiltered Cigarettes on Smoking Behavior and Toxicant Exposure: Protocol for a Randomized Crossover Clinical Trial (Preprint)

2020 ◽  
Author(s):  
Eyal Oren ◽  
Kim Pulvers ◽  
Devan R Romero ◽  
Casey Barber ◽  
Erika Carter ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Scientific Evidence ◽  
Research Question ◽  
Smoking Behavior ◽  
Baseline Period ◽  
Self Report ◽  
Future Research ◽  
Institutional Review Boards ◽  
Single Use ◽  
The Impact

BACKGROUND Plastic filters on cigarette butts are a widespread source of nonbiodegradable, toxic environmental waste. State and local legislation to ban the sale of single-use cigarettes may be considered to prevent this waste, but scientific evidence on the impact of switching smokers to unfiltered cigarettes on smoking behavior and toxicant exposures is needed to inform this policy. We have designed an open-label, randomized, 9-week, crossover clinical trial of adult filtered-cigarette smokers who switch to unfiltered cigarettes. OBJECTIVE Our objective is to understand the impact of switching smokers of filtered cigarettes to unfiltered cigarettes on smoking behavior and toxic exposures. METHODS This trial involves a 1-week baseline period; a 2-week period of smoking filtered or unfiltered cigarettes, where groups are randomly assigned; a 3-week washout period; another 1-week baseline period; and a 2-week crossover period of smoking the opposite condition (ie, filtered or unfiltered cigarettes) for a sufficient sample size of 40 participants. We will determine changes in (1) observed topography (ie, puff count, interpuff interval, and puff volume) and cigarettes smoked per day, via butt counts and self-report, (2) expired carbon monoxide and excretion of urinary cotinine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and volatile organic compounds, and (3) participants’ knowledge and attitudes toward unfiltered cigarettes, satisfaction with smoking, and intention to quit if they were not able to smoke filtered cigarettes. RESULTS This study was funded in June 2018 and approved by the relevant Institutional Review Boards in July 2018. This study has enrolled 37 participants as of October 2020. Data analysis is currently underway, and trial results are expected to be published in spring 2021. CONCLUSIONS This pilot proof-of-principle study will inform the design of a larger, future research project that can provide robust scientific evidence on our research question. Such a large study could inform possible state or local legislation to ban the sale of single-use filtered cigarettes in order to mitigate the environmental impact of discarded single-use plastic filters. CLINICALTRIAL ClinicalTrials.gov NCT03749876; https://clinicaltrials.gov/ct2/show/NCT03749876 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/19603

scholarly journals Design and Methods of a Randomized Cross-over Clinical Trial of Unfiltered Cigarettes on Smoking Behavior and Toxicant Exposure: Study Protocol for a Randomized Cross-over Clinical Trial

2020 ◽  
Author(s):  
Eyal Oren ◽  
Kim Pulvers ◽  
Devan R. Romero ◽  
Casey Barber ◽  
Erika Carter ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Scientific Evidence ◽  
Smoking Behavior ◽  
Baseline Period ◽  
Self Report ◽  
Open Label ◽  
Study Results ◽  
Single Use ◽  
State And Local ◽  
The Impact

Abstract Background: Plastic filters on cigarette butts are a widespread source of non-biodegradable, toxic environmental waste. State and local legislation to ban the sale of single-use cigarettes may be considered to prevent this waste, but scientific evidence on the impact of switching smokers to unfiltered cigarettes on smoking behavior and toxicant exposures is needed to inform this policy. We have designed an open-label, randomized, 9-week, cross-over clinical trial of adult filtered cigarette smokers who switch to unfiltered cigarettes.Methods: The trial involves a 1-week baseline period, 2 weeks of smoking filtered or unfiltered cigarettes (groups randomly assignd), a 3-week washout period, another 1-week baseline period, and a crossover to 2-weeks of smoking the opposite condition (filtered or unfiltered cigarettes). We will determine changes in: 1) observed topography (i.e., puff count, puff volume) and cigarettes smoked per day (via butt counts and self-report); 2) expired carbon monoxide (CO), urinary cotinine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and volatile organic compound (VOC) excretion; and 3) knowledge and attitudes toward unfiltered cigarettes, satisfaction with smoking, and intention to quit if they were not able to smoke filtered cigarettes.Discussion: This comprehensive proof-of-principle study will provide preliminary evidence to develop a research project with a larger sample size. Study results will inform proposed state or local legislation to ban the sale of single-use filtered cigarettes in order to eliminate the environmental impact of cigarette butt waste stemming from the single-use plastic filter. Trial Registration: NCT03749876

scholarly journals Global Impact of COVID-19 on Weight and Weight-Related Behaviors in the Adult Population: A Scoping Review

2021 ◽  
Vol 18 (4) ◽  
pp. 1876
Author(s):  
Han Shi Jocelyn Chew ◽  
Violeta Lopez
Keyword(s):  
Weight Gain ◽  
Scoping Review ◽  
Screen Time ◽  
Weight Status ◽  
Adult Population ◽  
Self Report ◽  
Future Research ◽  
Sedentary Behaviors ◽  
Management Interventions ◽  
The Impact

Objective: To provide an overview of what is known about the impact of COVID-19 on weight and weight-related behaviors. Methods: Systematic scoping review using the Arksey and O’Malley methodology. Results: A total of 19 out of 396 articles were included. All studies were conducted using online self-report surveys. The average age of respondents ranged from 19 to 47 years old, comprised of more females. Almost one-half and one-fifth of the respondents gained and lost weight during the COVID-19 pandemic, respectively. Among articles that examined weight, diet and physical activity changes concurrently, weight gain was reported alongside a 36.3% to 59.6% increase in total food consumption and a 67.4% to 61.4% decrease in physical activities. Weight gain predictors included female sex, middle-age, increased appetite, snacking after dinner, less physical exercise, sedentary behaviors of ≥6 h/day, low water consumption and less sleep at night. Included articles did not illustrate significant associations between alcohol consumption, screen time, education, place of living and employment status, although sedentary behaviors, including screen time, did increase significantly. Conclusions: Examining behavioral differences alone is insufficient in predicting weight status. Future research could examine differences in personality and coping mechanisms to design more personalized and effective weight management interventions.

Cognitive Impairment and Length of Stay in Acute Care Hospitals: A Scoping Review of the Literature

2021 ◽  
pp. 1-19
Author(s):  
Jonathan Plante ◽  
Karine Latulippe ◽  
Edeltraut Kröger ◽  
Dominique Giroux ◽  
Martine Marcotte ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Length Of Stay ◽  
Acute Care ◽  
Scoping Review ◽  
Research Question ◽  
Positive Association ◽  
Well Being ◽  
Future Research ◽  
Care Hospital ◽  
The Impact

Abstract Older persons experiencing a longer length of stay (LOS) or delayed discharge (DD) may see a decline in their health and well-being, generating significant costs. This review aimed to identify evidence on the impact of cognitive impairment (CI) on acute care hospital LOS/DD. A scoping review of studies examining the association between CI and LOS/DD was performed. We searched six databases; two reviewers independently screened references until November 2019. A narrative synthesis was used to answer the research question; 58 studies were included of which 33 found a positive association between CI and LOS or DD, 8 studies had mixed results, 3 found an inverse relationship, and 14 showed an indirect link between CI-related syndromes and LOS/DD. Thus, cognitive impairment seemed to be frequently associated with increased LOS/DD. Future research should consider CI together with other risks for LOS/DD and also focus on explaining the association between the two.

The Parent–Child Relationship and Sport Parents’ Experiences of Burnout and Engagement

2018 ◽  
Vol 12 (2) ◽  
pp. 218-233
Author(s):  
J.D. DeFreese ◽  
Travis E. Dorsch ◽  
Travis A. Flitton
Keyword(s):  
Youth Sport ◽  
Self Report ◽  
Future Research ◽  
Parent Child Relationship ◽  
Psychosocial Experiences ◽  
Child Relationship ◽  
Study Results ◽  
The Impact ◽  
Parents Experiences ◽  
Parent Child

Burnout and engagement are important psychological outcomes in sport with potential to impact athletes as well as sport parents. The present study examined associations among markers of the sport-based parent child-relationship (warmth and conflict) and parent burnout and engagement in organized youth sport. Youth sport parents (N = 214) aged 26–66 years (M = 43.2,SD = 6.2) completed valid and reliable self-report assessments of study variables. Study results showcased warmth, but not conflict, in the parent–child relationship as a significant negative contributor to global burnout and a significant positive contributor to global engagement in sport parents. Results offer preliminary insight into the impact of parent–child warmth in sport on parents’ experiences of burnout and engagement. Findings have implications for future research and practice designed to promote positive psychosocial experiences for sport families.

Self-Management of Arthritis

2017 ◽  
pp. 171-196
Author(s):  
Jessica M. Brooks ◽  
Kanako Iwanaga ◽  
Fong Chan
Keyword(s):  
Scientific Evidence ◽  
The United States ◽  
Self Management ◽  
Future Research ◽  
Counseling Services ◽  
Evidence Based ◽  
Physical Conditions ◽  
Current State ◽  
The Individual ◽  
The Impact

Arthritis is ranked among the top causes of disability in the United States and worldwide. Despite recent improvements in medications and medical treatment, there is no known cure for arthritis. Providing evidence-based psychoeducation and counseling services to people with arthritis lessens the impact of pain-related symptoms and disability on the individual and society. The purpose of this chapter is to provide an overview of the most common arthritic conditions, co-occurring physical conditions, and psychosocial factors associated with arthritis. Barriers to self-management and existing self-management programs are also discussed along with the current state of scientific evidence. The chapter concludes with some questions for future research.

The Impact of Share 35 Policy on Patient Survival in Patients Undergoing Liver Transplantation With Gender- and Race-Mismatched Donors

2018 ◽  
Vol 28 (2) ◽  
pp. 151-156
Author(s):  
Yefei Zhang ◽  
Maha R. Boktour
Keyword(s):  
Liver Transplantation ◽  
Proportional Hazards Model ◽  
Patient Survival ◽  
Research Question ◽  
Cox Proportional Hazards Model ◽  
Future Research ◽  
Gender And Race ◽  
Risk Of Death ◽  
Share 35 Policy ◽  
The Impact

Introduction: The United Network for Organ Sharing (UNOS) instituted the Share 35 policy in June 2013 in order to reduce death on liver transplant waitlist. The effect of this policy on patient survival among patients with gender- and race-mismatched donors has not been examined. Research Question: To assess the impact of Share 35 policy on posttransplantation patient survival among patients with end-stage liver disease (ESLD) transplanted with gender- and race-mismatched donors. Design: A total of 16 467 adult patients with ESLD who underwent liver transplantation between 2012 and 2015 were identified from UNOS. An overall Cox proportional hazards model adjusting for demographic, clinical, and geographic factors and separate models with a dummy variable of pre- and post-Share 35 periods as well as its interaction with other factors were performed to model the effect of gender and race mismatch on posttransplantation patient survival and to compare the patient survival differences between the first 18 months of Share 35 policy to an equivalent time period before. Results: Comparison of the pre- and post-Share 35 periods did not show significant changes in the numbers of gender- and race-mismatched transplants, or the risk of death for gender-mismatched recipients. However, black recipients with Hispanic donors (hazard ratio: 0.51, 95% confidence interval, 0.29-0.90) had significantly increased patient survival after Share 35 policy took effect. Conclusion: The Share 35 policy had a moderate impact on posttransplantation patient survival among recipients with racially mismatched donors according to the first 18-month experience. Future research is recommended to explore long-term transplantation.

scholarly journals The Impact of Cognitive Anxiety and the Rating of Pain on Care Processes in a Vigilance Task: The Important Part Played by Age

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Luis Pinel ◽  
Miguel A. Perez-Nieto ◽  
Marta Redondo ◽  
Luis Rodríguez-Rodríguez ◽  
Leticia L. Mateos
Keyword(s):  
Chronic Pain ◽  
Linear Regression Analysis ◽  
Public Health Problem ◽  
Vigilance Task ◽  
Significant Negative Correlation ◽  
Self Report ◽  
Future Research ◽  
Mcgill Pain Questionnaire ◽  
Cognitive Anxiety ◽  
The Impact

Chronic pain is a serious public health problem that has grown exponentially in recent years, which is why it has received the attention of numerous researchers. Most of the studies in the field of chronic pain have focused on care as a mediating variable on the perception of painful stimuli and emotions. Nevertheless, there are very few studies that have gone in the opposite direction. This study’s aim is therefore to analyse the impact of emotional variables (anxiety and depression), the rating of pain, and age on vigilance processes in a sample of patients with chronic pain. To do so, the attentional performance of a cohort of 52 patients with chronic pain was measured through the use of a modified dot-probe task. Furthermore, all the participants were evaluated using the following self-report measures: Beck’s Depression Inventory-II (BDI-II), the McGill Pain Questionnaire, and the Pain Anxiety Symptoms Scale-20 (PASS-20). Stepwise multiple linear regression analysis revealed a significant negative correlation between the pain rating index and the number of mistakes the participants made during the attention test. There was also a positive and significant correlation with age and another negative and significant correlation with cognitive anxiety regarding the overall performance times during the undertaking of the experimental task. These results point to the importance of a more in-depth understanding of the impact that the emotional variables and other variables such as age have on attentional processes and the rating of pain. Finally, the discussion focuses on the implications these results could have for clinical practice or for future research studies in this field.

Using self-report and skin conductance measures to evaluate theme park experiences

2020 ◽  
pp. 135676672096973
Author(s):  
Shanshi Li
Keyword(s):  
Skin Conductance ◽  
Self Report ◽  
Future Research ◽  
Theme Park ◽  
Retrospective Evaluation ◽  
Report Data ◽  
Self Report Data ◽  
Affective Intensity ◽  
The Impact ◽  
Practical Implications

This study examines the impact of the key affective moments of a theme park experience on visitors’ post-trip evaluations measured immediately after their visits. One hundred and twenty-three participants visited a theme park while their real-time skin conductance and self-report data were collected. Results indicate that visitors’ pleasure levels (i.e. average, beginning, peak, and end) consistently correlate with satisfaction, which in turn, positively influences behavioural intention. In particular, visitors’ satisfaction levels are better aligned with the affective intensity at the end moment and the average emotion intensity of a theme park experience. Arousal, however, was not found to be a significant indicator of post-trip evaluation. The study extends literature on key moments and retrospective evaluation by illustrating how visitors rely on affective moments of a theme park experience to construct overall evaluations. The study concludes with practical implications and scope for future research.

A snapshot of psycho-social issues in camp living. A Sri Lankan landslide May 2016 in the Kegalle district

2018 ◽  
Author(s):  
Matt Broadway-Horner 1
Keyword(s):  
Professional Growth ◽  
Social Issues ◽  
Lessons Learned ◽  
Self Report ◽  
Future Research ◽  
Trauma Symptoms ◽  
Internally Displaced ◽  
Graduate Degrees ◽  
Adolescents And Adults ◽  
The Impact

This paper seeks to explore the aspects of being made homeless or Internally Displaced person (IDP) and how the team attempted to assess this. The team of 10 psychological researchers and statisticians spent a day at 5 camps in 4 locations within Kegalle, Sri Lanka. The languages within the team are Tamil, English and Sinhalese. The aim to find out if depression, anxiety and trauma symptoms are evident within child, adolescents and adults categories, 3 months after the landslide triggered by the storm Roanu May 2016. The participants volunteered to be interviewed using self report measures. The psychological researchers did have undergraduate and post graduate degrees in psychology. Whilst the project lead had clinical experience, the researchers did not and so this was their first field trip. The research was granted ethical clearance by the ethics board at CIRP – Colombo. Unfortunately, due to low numbers, significance is problematic and so this paper addresses the experience and lessons learned by implication for professional growth and future research with IDP. But the impact upon men’s health becomes clear as the team discovers the psychosocial aspects of being homeless.

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