scholarly journals A Focus on the HIV Care Continuum Through the Healthy Young Men’s Cohort Study: Protocol for a Mixed-Methods Study

10.2196/10738 ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. e10738 ◽  
Author(s):  
Michele D Kipke ◽  
Katrina Kubicek ◽  
Carolyn F Wong ◽  
Yolo Akili Robinson ◽  
Ifedayo C Akinyemi ◽  
...  
2018 ◽  
Author(s):  
Michele D Kipke ◽  
Katrina Kubicek ◽  
Carolyn F Wong ◽  
Yolo Akili Robinson ◽  
Ifedayo C Akinyemi ◽  
...  

BACKGROUND No group is at greater risk for acquiring HIV than young men who have sex with men (YMSM), particularly black or African American (AA) and Hispanic or Latino (L) YMSM living in inner cities, who account for the largest number of new HIV infections each year. Although pre-exposure prophylaxis (PrEP), postexposure prophylaxis (PEP), and treatment as prevention hold enormous promise for changing the course of the epidemic, AA/L-YMSM are the least likely population to be receiving primary health care and HIV prevention/care and are the least likely to be using PrEP and PEP. OBJECTIVE The overarching aim of the Healthy Young Men’s (HYM) cohort study is to conduct longitudinal research with a cohort of AA/L-YMSM to prevent new HIV infections, reduce transmission, and reduce HIV/AIDS-related disparities by focusing on successful engagement in care. Findings from this research will be used to inform the development of new interventions designed to engage AA/L-YMSM in the HIV prevention and care continua. METHODS Longitudinal research (baseline and follow-up assessments every 6 months for a total of 8 waves of data collection) is ongoing with a new cohort of 450 high-risk AA/L-YMSM in Los Angeles. Participants were recruited using a venue-based and social media sampling design. In addition to self-report surveys, the study protocol includes the collection of urine to assess recent use of illicit drugs and the collection of blood and rectal/throat swabs to test for current sexually transmitted infection (STI)/HIV infection. An additional sample of blood/plasma (10 mL for 4 aliquots and 1 pellet) is also collected and stored in the HYM cohort study biorepository for future research. By design, we recruited 400 HIV-negative participants and 50 HIV-positive (HIV+) participants. This mixed-methods study design includes collection and triangulated analysis of quantitative, qualitative, and biological measures (ie, drug use, STI/HIV testing, and adherence to antiretroviral therapy among HIV+ participants) at baseline and every 6 months. The HYM cohort study will provide a platform from which new and emerging biomedical prevention strategies (eg, PrEP, rectal microbicides, and PEP) and other HIV prevention and care engagement interventions can be developed and evaluated with AA/L-YMSM. RESULTS To date, all participants in the HYM cohort study have been recruited and baseline assessment has been conducted. CONCLUSIONS The findings from this research will be used to inform the development of new and/or adaptation of existing evidence-based HIV prevention interventions and interventions designed to engage this population in the HIV prevention and care continua. INTERNATIONAL REGISTERED REPOR DERR1-10.2196/10738


2018 ◽  
Vol 29 (3) ◽  
pp. 475-478 ◽  
Author(s):  
Richard E. Greene ◽  
Albert Luong ◽  
Staci C. Barton ◽  
Farzana Kapadia ◽  
Perry N. Halkitis

2017 ◽  
Vol 20 (1) ◽  
pp. 21848 ◽  
Author(s):  
Sophia A. Hussen ◽  
Rana Chakraborty ◽  
Andrea Knezevic ◽  
Andres Camacho-Gonzalez ◽  
Eugene Huang ◽  
...  

2002 ◽  
Vol 117 (3) ◽  
pp. 231-232 ◽  
Author(s):  
T.Anne Richards ◽  
Karen Vernon ◽  
Herminia Palacio ◽  
James G Kahn ◽  
Stephen F Morin

2021 ◽  
Vol 24 (5) ◽  
Author(s):  
Nathaniel T Yohannes ◽  
Cathy A Jenkins ◽  
Kate Clouse ◽  
Claudia P Cortés ◽  
Fernando Mejía Cordero ◽  
...  

2021 ◽  
Vol 18 (3) ◽  
pp. 229-236
Author(s):  
Jessica P. Ridgway ◽  
Alice Lee ◽  
Samantha Devlin ◽  
Jared Kerman ◽  
Anoop Mayampurath

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S473-S473
Author(s):  
Christina Rizk ◽  
Alice Zhao ◽  
Janet Miceli ◽  
Portia Shea ◽  
Merceditas Villanueva ◽  
...  

Abstract Background It is estimated that 1,295 per 100,000 are people living with HIV (PLWH) in New Haven, which is the second highest rate of HIV prevalence in Connecticut. Since 2009, New Haven has established the Ryan White (RW) HIV Care Continuum. The main goals of HIV care are early linkage to care, ART initiation, and HIV viral suppression. This study is designed to understand the trends and outcomes in newly diagnosed PLWH in New Haven County. Methods This study is a retrospective medical record review of all newly diagnosed RW eligible PLWH from January 1, 2009 to December 31, 2018. The data were collected in REDCap database and included demographics, HIV risk factor, presence of mental health and/or substance abuse disorder, date of diagnosis, date of initial visit, and ART initiation. Health outcomes such as AIDS at diagnosis and rate of viral suppression were evaluated. The data were then analyzed to show the trends over 10 years. Results From January 1, 2009 to December 31, 2018 there were 420 newly diagnosed RW PLWH. Sixty-seven percent of those were male, 56% were non-white, 47% self-identified as Men who have Sex with Men (MSM), and 41% were heterosexual. Twenty-nine percent had AIDS-defining condition at the time of the diagnosis. Thirty-four percent of the 420 patients had a mental health and/or substance use disorder; 53% of those were MSM and 51% were non-white. Over the 10-year period, it was noted that the duration between date of HIV diagnosis and linkage to care as well as ART initiation decreased. This decline was associated with a substantial increase in viral suppression. The average time between the dates of HIV diagnosis and initial visit decreased from 269 days in 2009 to 13 days in 2018. Moreover, the average time between the dates of diagnosis and ART initiation dropped from 308 days in 2009 to 15 days in 2018. The 1-year HIV viral suppression rate subsequently doubled from 44% in 2009 to 87% in 2018 (P < 0.01). Conclusion The Ryan White HIV Care Continuum Model with emphasis on early linkage to care and ART initiation can have a significant impact on HIV viral suppression at a community level for newly diagnosed patients. Another important observation in this study was the alarming high rate of AIDS at diagnosis, which highlights the need for universal HIV testing, and early diagnosis. Disclosures All authors: No reported disclosures.


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