Value of Panendoscopy in the Identification of Synchronous Malignancies in Patients Suffering from Oral Squamous Cell Carcinoma Without Clinical Signs of a Second Primary Tumor

2021 ◽  
Vol 41 (4) ◽  
pp. 2039-2044
Author(s):  
STEFFEN KOERDT ◽  
JAN-DIRK RAGUSE ◽  
FELIX NEUMANN ◽  
BENEDICTA BECK-BROICHSITTER ◽  
KILIAN KREUTZER ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Clinical Signs ◽  
Second Primary ◽  
Second Primary Tumor ◽  
Synchronous Malignancies

PATIENT WITH SQUAMOUS CELL CARCINOMA AND SECOND PRIMARY TUMOR ON THE LIPS: A CASE REPORT

2020 ◽  
Vol 130 (3) ◽  
pp. e144
Author(s):  
ANTONIA TAIANE LOPES DE MORAES ◽  
YASMIM RODRIGUES SENA ◽  
KAROLYNY MARTINS BALBINOT ◽  
BEATRIZ VOSS MARTINS ◽  
SÂMIA CORDOVIL DE ALMEIDA
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Second Primary ◽  
Second Primary Tumor

Cisplatin-fluorouracil exclusive chemotherapy for T1-T3N0 glottic squamous cell carcinoma complete clinical responders: five-year results.

1996 ◽  
Vol 14 (8) ◽  
pp. 2331-2336 ◽  
Author(s):  
O Laccourreye ◽  
D Brasnu ◽  
V Bassot ◽  
M Ménard ◽  
D Khayat ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Local Recurrence ◽  
Cell Carcinoma ◽  
Local Control ◽  
Squamous Cell ◽  
Distant Metastasis ◽  
Primary Tumor ◽  
Second Primary ◽  
Nodal Recurrence ◽  
Second Primary Tumor

PURPOSE To evaluate cisplatin-fluorouracil exclusive chemotherapy (EC) for T1-T3N0 glottic squamous cell carcinoma complete clinical responders (CCR) after cisplatin-fluorouracil induction chemotherapy (IC). PATIENTS AND METHODS A retrospective analysis was performed of 58 patients with T1-T3N0 glottic squamous cell carcinoma CCR after IC consecutively managed at our department between 1985 and 1992. Twenty-one CCR were managed with EC. Thirty-seven CCR were managed with IC and a conventional laryngeal-preservation modality. Analyses of survival, local control, nodal recurrence, distant metastasis, and metachronous second primary tumor were performed using the Kaplan-Meier actuarial life-table method. In CCR managed with EC, the independent factors of age, tumor classification, exact tumor location, true vocal cord motion, arytenoid cartilage motion, total dosage of drugs delivered, and number of courses received were tested for potential correlation with survival, local recurrence, nodal recurence, and distant metastasis. RESULTS The 5-year survival, local control, nodal recurrence, distant metastasis, and metachronous second primary tumor rates in CCR managed with EC were 95.2%, 70.7%, 0%, 0%, and 14.3%, respectively. The 5-year rates of survival, local control, nodal recurrence, distant metastasis, and metachronous second primary tumor in CCR managed with IC and a conventional laryngeal-preservation modality were 86.1%, 97%, 2.7%, 6%, and 14.5%, respectively. Local recurrence was statistically more likely in CCR managed with EC (P = .002). Local recurrence in CCR managed with EC was always salvaged with partial laryngectomy or radiation therapy, which resulted in an overall 100% local control and laryngeal-preservation rate within this group. In CCR managed with EC, none of the variables analyzed was statistically related to survival, local recurrence, nodal recurrence, or distant metastasis. CONCLUSION The present retrospective studies demonstrated that within T1-T3N0 glottic squamous cell carcinoma CCR, there is clearly a significant subset of patients with chemocurable tumors who achieved both perfect preservation of structure-supporting voice and long-term survival after EC. Careful monthly follow-up evaluation allowed for timely successful salvage of local recurrence after EC without the need for total laryngectomy. Such management did not appear to increase the risk for subsequent nodal failure, subsequent distant metastasis, or reduced survival.

scholarly journals Notch Intracellular Domain (NICD) Expression and Clinical Manifestations of Second Primary Tumor at Esophagus in Patients with Head and Neck Squamous Cell Carcinoma

2019 ◽  
Vol Volume 12 ◽  
pp. 11175-11181
Author(s):  
Tauangtham Anekpuritanang ◽  
Warut Pongsapich ◽  
Tanasarun Watcharadilokkul ◽  
Premyot Ngaotepprutaram ◽  
Paveena Pithuksurachai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Clinical Manifestations ◽  
Neck Squamous Cell Carcinoma ◽  
Second Primary ◽  
Second Primary Tumor ◽  
Notch Intracellular Domain

scholarly journals Aggressiveness pattern and second primary tumor risk associated with basaloid squamous cell carcinoma of the larynx

Oncotarget ◽  
2017 ◽  
Vol 8 (56) ◽  
pp. 95791-95798 ◽  
Author(s):  
Filippo Ricciardiello ◽  
Michele Caraglia ◽  
Brigida Iorio ◽  
Teresa Abate ◽  
Mariarosaria Boccellino ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Second Primary ◽  
Basaloid Squamous Cell Carcinoma ◽  
Second Primary Tumor ◽  
Tumor Risk ◽  
Carcinoma Of The Larynx ◽  
Basaloid Squamous

scholarly journals The poor outcome of second primary oral squamous cell carcinoma is attributed to Bmi1 upregulation

2018 ◽  
Vol 7 (4) ◽  
pp. 1056-1069 ◽  
Author(s):  
Qinchao Hu ◽  
Tong Wu ◽  
Xiaobing Chen ◽  
Huan Li ◽  
Zhicheng Du ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Second Primary ◽  
Poor Outcome ◽  
The Poor

Molecular events in relapsed oral squamous cell carcinoma: Recurrence vs secondary primary tumor

Oral Oncology ◽  
2015 ◽  
Vol 51 (8) ◽  
pp. 738-744 ◽  
Author(s):  
Frederico O. Gleber-Netto ◽  
Boudewijn J.M. Braakhuis ◽  
Asterios Triantafyllou ◽  
Robert P. Takes ◽  
Natalie Kelner ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Molecular Events ◽  
Secondary Primary Tumor

Primary tumor induces sentinel lymph node lymphangiogenesis in oral squamous cell carcinoma

Oral Oncology ◽  
2010 ◽  
Vol 46 (5) ◽  
pp. 373-378 ◽  
Author(s):  
Hiroki Ishii ◽  
Kazuaki Chikamatsu ◽  
Koichi Sakakura ◽  
Masanori Miyata ◽  
Nobuhiko Furuya ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor

Risk of second primary cancer in oral squamous cell carcinoma

Head & Neck ◽  
2020 ◽  
Vol 42 (8) ◽  
pp. 1848-1858
Author(s):  
Rayan Mroueh ◽  
Aapeli Nevala ◽  
Aaro Haapaniemi ◽  
Janne Pitkäniemi ◽  
Tuula Salo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Second Primary ◽  
Primary Cancer ◽  
Second Primary Cancer
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