scholarly journals Investigation of Survivin Gene Polymorphism and Serum Survivin Levels in Patients with Brain Tumors

2018 ◽  
Vol 38 (10) ◽  
pp. 5991-5998 ◽  
Author(s):  
DIDEM KAFADAR ◽  
ILHAN YAYLIM ◽  
ALI METIN KAFADAR ◽  
CANAN CACINA ◽  
ARZU ERGEN ◽  
...  
2012 ◽  
Vol 208 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Nasrin Yazdani ◽  
Forough A. Sayahpour ◽  
Vahid Haghpanah ◽  
Parvin Amiri ◽  
Maryam Shahrabi-Farahani ◽  
...  

2012 ◽  
Vol 22 (1) ◽  
pp. 35-37 ◽  
Author(s):  
Parisa Zahedi ◽  
Soheila Aminimoghaddam ◽  
Forough A. Sayahpour ◽  
Vahid Haghpanah ◽  
Parvin Amiri ◽  
...  

ObjectiveSurvivin is an inhibitor of apoptosis protein, which is up-regulated in endometrial cancer (EC). A promoter region polymorphism (−31G/C) in the survivin gene has been reported as a modulator of gene expression. The aim of this study was to explore the frequency of survivin −31G/C polymorphism in tumor tissues from patients with EC in an Iranian population compared to that of healthy controls.Materials and MethodsParaffin-embedded tissue sections from patients diagnosed with EC (n = 31) and healthy controls (n = 30) were examined. Genotyping for survivin −31G/C polymorphism was performed using polymerase chain reaction (PCR) restriction fragment length polymorphism (RFLP).ResultsThe presence of allele C was found to be significantly increased in EC tissues compared to the healthy tissues (GG vs GC + CC, P = 0. 01; OR, 3.6; 95% CI, 1.1–11.9).ConclusionOur data are in keeping with a previous finding regarding the role of survivin gene polymorphism in malignancies. This finding highlights the role of survivin in pathogenesis of various carcinomas, which might have therapeutic implications.


2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A417-A417
Author(s):  
S. Radojevic-Skodric ◽  
G. Basta-Jovanovic ◽  
D. Brasanac ◽  
N. Nikolic ◽  
L. Bogdanovic ◽  
...  

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Sadrettin Pence ◽  
Canan Cacina ◽  
Saime Turan ◽  
Feyza Genc ◽  
Ali Kafadar ◽  
...  

2013 ◽  
Vol 17 (1) ◽  
pp. 74-77 ◽  
Author(s):  
Leila Vazifeh Mostaan ◽  
Azin Tabari ◽  
Parvin Amiri ◽  
Mohammadtaghi Khorsandi Ashtiani ◽  
Aydin Mahdkhah ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A709-A709
Author(s):  
A TAKAGI ◽  
J XUAN ◽  
R DEGUCHI ◽  
J NAGATA ◽  
H KIJIMA ◽  
...  

1992 ◽  
Vol 3 (4) ◽  
pp. 781-789 ◽  
Author(s):  
J. Russell Geyer
Keyword(s):  

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