scholarly journals Prognostic Factors for Survival in Patients Treated with Multimodal Therapy for Anaplastic Thyroid Cancer

2016 ◽  
Vol 36 (9) ◽  
pp. 4697-4700 ◽  
Author(s):  
LUKAS KÄSMANN ◽  
LOUISA BOLM ◽  
STEFAN JANSSEN ◽  
DIRK RADES
Keyword(s):  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Multimodal Therapy ◽  
Anaplastic Thyroid Cancer

scholarly journals Expression of PD-1 and PD-L1 in Anaplastic Thyroid Cancer Patients Treated With Multimodal Therapy: Results From a Retrospective Study

2017 ◽  
Vol 102 (6) ◽  
pp. 1943-1950 ◽  
Author(s):  
Ashish V. Chintakuntlawar ◽  
Kandelaria M. Rumilla ◽  
Carin Y. Smith ◽  
Sarah M. Jenkins ◽  
Robert L. Foote ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Retrospective Study ◽  
Cancer Patients ◽  
Multimodal Therapy ◽  
Anaplastic Thyroid Cancer

scholarly journals Classification, gradation, prognostic factors and risk factors for thyroid carcinoma

2003 ◽  
Vol 50 (3) ◽  
pp. 56-60
Author(s):  
Vladan Zivaljevic ◽  
Ivan Paunovic ◽  
Aleksandar Diklic ◽  
Ksenija Krgovic ◽  
Rastko Zivic ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Thyroid Carcinoma ◽  
Multiple Endocrine Neoplasia ◽  
Endemic Goiter ◽  
Anaplastic Thyroid Cancer ◽  
External Radiation ◽  
Follicular Cells ◽  
Follicular Thyroid Cancer ◽  
Area Increase

Thyroid carcinomas arise from follicular cells (papillary, follicular, Hurthle, anaplastic), parafollicular cells (medullary) and stroma (lymphoma, sarcoma?). Gradation and prognostic factors are different for every one of histological type. Most patients with papillary and follicular thyroid cancer have an excellent prognosis. At the other extreme is anaplastic thyroid cancer whose usual mean survival can be measured in months. Exposure to external radiation and living in endemic goiter area increase the frequency of thyroid cancer. Medullary thyroid carcinoma is often familial and may occur in associations with the multiple endocrine neoplasia syndromes.

Anaplastic Thyroid Cancer (ATC): Prognostic Factors, Patterns of Care, and Overall Survival

2016 ◽  
Vol 94 (4) ◽  
pp. 950-951 ◽  
Author(s):  
S.M. Glaser ◽  
S.F. Mandish ◽  
B.S. Gill ◽  
G. Balasubramani ◽  
D.A. Clump ◽  
...  
Keyword(s):  
Overall Survival ◽  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Anaplastic Thyroid Cancer ◽  
Patterns Of Care

Anaplastic thyroid cancer: Prognostic factors, patterns of care, and overall survival

Head & Neck ◽  
2016 ◽  
Vol 38 (S1) ◽  
pp. E2083-E2090 ◽  
Author(s):  
Scott M. Glaser ◽  
Steven F. Mandish ◽  
Beant S. Gill ◽  
Goundappa K. Balasubramani ◽  
David A. Clump ◽  
...  
Keyword(s):  
Overall Survival ◽  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Anaplastic Thyroid Cancer ◽  
Patterns Of Care

scholarly journals Outcomes of multimodal therapy in a large series of patients with anaplastic thyroid cancer

Cancer ◽  
2019 ◽  
Vol 126 (2) ◽  
pp. 444-452 ◽  
Author(s):  
Dan Fan ◽  
Jennifer Ma ◽  
Andrew C. Bell ◽  
Andries H. Groen ◽  
Kyrie S. Olsen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Multimodal Therapy ◽  
Anaplastic Thyroid Cancer ◽  
Large Series

scholarly journals A Case of Recurrent Anaplastic Thyroid Cancer Treated by Lenvatinib after Successful Long-term Multimodal Therapy

2016 ◽  
Vol 77 (2) ◽  
pp. 291-295 ◽  
Author(s):  
Naoyoshi ONODA ◽  
Mao TOKUMOTO ◽  
Satoru NODA ◽  
Go OHIRA ◽  
Shinichiro KASHIWAGI ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Multimodal Therapy ◽  
Anaplastic Thyroid Cancer

scholarly journals Radiotherapy Plus Chemotherapy Leads to Prolonged Survival in Patients With Anaplastic Thyroid Cancer Compared With Radiotherapy Alone Regardless of Surgical Resection and Distant Metastasis: A Retrospective Population Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Weili Zhou ◽  
Yangyang Yue ◽  
Xin Zhang
Keyword(s):  
Thyroid Cancer ◽  
Prognostic Factors ◽  
Surgical Resection ◽  
Distant Metastasis ◽  
Anaplastic Thyroid Cancer ◽  
Inverse Probability Weighting ◽  
Probability Weighting ◽  
Compete Risk Model ◽  
Inverse Probability ◽  
Radiotherapy Alone

BackgroundWhether anaplastic thyroid cancer (ATC) patients benefit more from radiotherapy plus chemotherapy (RCT) than from radiotherapy alone (RT) was controversial. We aimed to investigate the effectiveness of RCT versus RT on ATC overall and within subgroups by surgical resection and distant metastasis in a large real-world cohort.MethodsPatients with ATC diagnosed between 2004 and 2015 were identified from the Surveillance, Epidemiology, and End Results Program database. Inverse probability weighting (IPW) was performed to balance variables between the two groups. Multivariate Cox proportional hazard model and Fine-Gray compete-risk model were carried out to investigate prognostic factors relating to overall survival (OS) and cancer-specific survival (CSS). Subgroup analysis was carried out, and a forest plot was graphed.ResultsOf the 491 ATC patients, 321 (65.4%) were in the RCT group and 170 (34.6%) were in the RT group. The median OS was 4 months [interquartile range (IQR) 2–7] and 2 months (IQR 1–4) for patients in the RCT and RT groups, respectively. As indicated by the inverse probability weighting multivariate regression, RCT was associated with significantly improved OS (adjusted HR = 0.69, 95% CI = 0.56–0.85, p < 0.001) and CSS (adjusted subdistribution HR = 0.77, 95% CI = 0.61–0.96, p = 0.018). The prominent effect of RCT versus RT alone remains significant within each subgroup stratified by surgical resection and distant metastasis. Older age, single marital status, surgical resection, distant metastasis, and tumor extension were significant prognostic factors of survival.ConclusionsRCT contributes to prolonged OS and CSS compared with RT alone in ATC patients, regardless of surgical resection and distant metastasis. RCT should be preferentially applied to ATC patients.

scholarly journals Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer

2017 ◽  
Vol 102 (12) ◽  
pp. 4506-4514 ◽  
Author(s):  
Naiyarat Prasongsook ◽  
Aditi Kumar ◽  
Ashish V Chintakuntlawar ◽  
Robert L Foote ◽  
Jan Kasperbauer ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Multimodal Therapy ◽  
Anaplastic Thyroid Cancer
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