scholarly journals Pressure Pain Threshold Changes in Masseter Muscle before and after Sustained Maximum Volunary Contraction in the Patients with Masticatory Muscle Pain.

1998 ◽  
Vol 42 (2) ◽  
pp. 220-226 ◽  
Author(s):  
Takanori Kanda
2018 ◽  
Vol 7 (11) ◽  
pp. 454 ◽  
Author(s):  
David Rodríguez-Sanz ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
Marta Losa-Iglesias ◽  
Eva Martínez-Jiménez ◽  
Daniel Muñoz-García ◽  
...  

Objective: To assess clinical differences in the Achilles tendons of runners with ankle equinus wearing either compressive or standard stockings. Design: Case–control study. Methods: In this study, we conducted clinical examinations of 98 sportsmen (runners) with equinus, before and after 30 min of running on a treadmill; 49 runners wore compressive stockings and 49 wore standard stockings. Clinical assessments of the runners’ Achilles tendons were based on the pressure pain threshold (PPT) and skin temperature analysis. Results: Achilles tendon evaluations identified significant differences in skin temperature modification and PPT between the compressive and standard stocking groups. Conclusions: Based on our findings, we propose that higher skin temperatures are associated with lower pressure pain thresholds in the Achilles tendons of runners with ankle equinus.


2014 ◽  
Vol 93 (4) ◽  
pp. 299-309 ◽  
Author(s):  
Chu-Hsu Lin ◽  
Kai-Hua Chen ◽  
Chia-Hao Chang ◽  
Chien-Min Chen ◽  
Ying Chih Huang ◽  
...  

2019 ◽  
Vol 20 (1) ◽  
pp. 139-150
Author(s):  
Suzan Meijs ◽  
Shaojun Liao ◽  
Lars Arendt-Nielsen ◽  
Kelun Wang ◽  
Brian E. Cairns

AbstractBackground and aimsPreclinical studies have reported that activation of peripheral γ-aminobutyric acid A (GABAA) receptors may result in analgesia. The current study was conducted in young healthy men (n = 30) and women (n = 28) to determine whether injections of GABA into the masseter muscle reduce pain in a sex-related manner.MethodsThe effect of injection of GABA alone, or in combination with the non-inflammatory algogen glutamate, was assessed in two separate studies. Lorazepam, a positive allosteric modulator of the GABAA-receptor, was co-injected with GABA in both studies to explore the role of this receptor in muscle pain responses of healthy human volunteers. Masticatory muscle mechanical pain intensity was recorded on an electronic visual analogue scale (VAS) while muscle pain sensitivity was assessed by determining the pressure pain threshold (PPT), tolerance and maximal jaw opening (MJO) of the subjects prior to, and again after the various intramuscular injections.ResultsIntramuscular injection of GABA alone was reported to be significantly more painful, in a concentration related manner, than saline control injections, and this pain was further increased by co-injection of lorazepam with GABA. Co-injection of GABA with glutamate was found to significantly increase glutamate-evoked masseter muscle pain in men, but not in women. There was no effect of injections of either GABA alone, or GABA with glutamate, on PPT, tolerance or maximum jaw opening.ConclusionsInjection of GABA into the human masseter muscle appears to excite nociceptors to produce muscle pain without a longer term effect on mechanical pain sensitivity in the muscle. The findings suggest that GABA-mediated pain in humans is produced through peripheral GABAA receptor activation. The mechanism underlying the sex-related difference in the effect of GABA on glutamate-evoked muscle pain was speculated to be due to a methodological artifact.ImplicationsThis study was designed to detect analgesic rather than algesic effects of peripherally administered GABA, and as a result, the concentration of glutamate chosen for injection was close to the maximal pain response for healthy women, based on previously determined pain-concentration response relationships for glutamate. This may explain the finding of greater pain in men than women, when GABA and glutamate were co-injected. Overall, the findings suggest that activation of peripheral GABAA receptors in human masticatory muscle produces pain, possibly due to depolarization of the masticatory muscle afferent fibers.


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