scholarly journals Influence of Glucosaminilemuramylpentapeptide on the Functional Peculiarities of the Respiratory System and the Dynamics of IL-6 in Patients with Infiltrative Tuberculosis Combined with Chronic Bronchitis

2017 ◽  
Vol 24 (3) ◽  
Author(s):  
Olha Melnyk-Sheremeta ◽  
Mykola Ostrovskyy
Keyword(s):  
Chronic Bronchitis ◽  
Respiratory System ◽  
Bronchial Obstruction ◽  
Dynamic Changes ◽  
Basic Therapy ◽  
Immune Modulator ◽  
Pulmonary System ◽  
Bronchial Mucous Membrane ◽  
Nonspecific Inflammation

The aim of our study was to evaluate the functional peculiarities of the respiratory system and the dynamics of IL-6 in patients with infiltrative tuberculosis combined with chronic bronchitis.Materials and methods. There were examined 40 patients with infiltrative tuberculosis combined with chronic bronchitis: 18 patients receiving basic therapy according to the category and 22 patients who were added glucosaminilemuramylpentapeptide to basic therapy. Determination of IL-6 in bronchoalveolar content was performed by ELISA analysis.Results. The additional inclusion of glucosaminilemuramylpentapeptide into the complex therapy of patients with infiltrative tuberculosis combined with chronic bronchitis in acute phase manifests itself with positively aimed dynamic changes of the bronchial mucous membrane according to the data of endoscopy. The standard scheme of treatment combined with immune modulator affects the recovery of lung function in comorbidity of pathologies explaining it as the action of the means aimed at enhancing of sanogenetic mechanisms of liquidation of combination of specific and nonspecific inflammation in the broncho-pulmonary system, and thus – the reduction of the basis for secondary bronchial obstruction. The results of this study indicate the advisability of administration of immune modulator of muramylpeptide series.

scholarly journals Erythrocyte Antioxidative Enzymes in Experimentally Induced Osteopenia in Rats

2012 ◽  
Vol 56 (4) ◽  
pp. 669-675 ◽  
Author(s):  
Radosław P. Radzki ◽  
Marek Bieńko ◽  
Edyta Albera ◽  
Marta Kankofer
Keyword(s):  
Mineral Content ◽  
Mineral Density ◽  
Initial Body Weight ◽  
Dynamic Changes ◽  
Bone Parameters ◽  
Dynamic Relationship ◽  
Healthy Female ◽  
Female Wistar Rats ◽  
Determination Of Activity

Abstract The study aimed at the determination of dynamic relationship between mineralisation processes and antioxidative/oxidative status during the development of osteopenia. One hundred and two healthy female Wistar rats at the age of 2 months and initial body weight of 200 g were used in the experiment. The rats were divided into control (CON, n=6), sham operated (SHO, n=48), and ovariectomised (OVX, n=48) groups. Animals from SHO (n=6) and OVX (n=6) groups were sacrificed every week during 8 weeks of the experiment in order to detect dynamic changes in examined parameters. The samples were collected weekly from day 7 to day 56. The femora were examined with the use of DXA (bone mineral density) and pQCT (area, mineral content, volumetric density of trabecular and cortical part of distal femora). The pQCT scans were performed 5 mm from distal end of the tibia. The determination of activity of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in haemolysates of erythrocytes were performed spectrophotometrically. Obtained data showed wave like changes in both enzyme activities and bone parameters and indicated the importance of the 2nd-3rd and 5th-6th week after surgery as a key moment for bone metabolism and activity of enzymatic antioxidative defence during the development of osteopenia induced by bilateral ovariectomy. The obtained results proved that alterations in activity of GSH-Px and SOD, and pQCT ahead the changes registered by DXA by 7 d.

scholarly journals 173 DETERMINATION OF TOTAL. RESPIRATORY SYSTEM COMPLIANCE FROM RESONANT FREQUENCY IN INTUBATED SLBJECTS

1990 ◽  
Vol 28 (3) ◽  
pp. 306-306
Author(s):  
Andreas Schulze ◽  
Peter Schaller ◽  
Jürgen Dinger ◽  
Dieter Gmyrek
Keyword(s):  
Resonant Frequency ◽  
Respiratory System ◽  
Respiratory System Compliance

105-PA11 The importance of reversibility in the assessment of different bronchial obstruction in asthma and chronic bronchitis

1995 ◽  
Vol 76 ◽  
pp. 62-63
Author(s):  
E. Öztürk ◽  
Y. Yilmazkaya ◽  
A. Hazar ◽  
S. Kuleci ◽  
M. Kurutepe
Keyword(s):  
Chronic Bronchitis ◽  
Bronchial Obstruction

Interrupter airway and tissue resistance: errors caused by valve properties and respiratory system compliance

1999 ◽  
Vol 87 (4) ◽  
pp. 1546-1554 ◽  
Author(s):  
Volker Kessler ◽  
Georg Mols ◽  
Holger Bernhard ◽  
Christoph Haberthür ◽  
Josef Guttmann
Keyword(s):  
Computer Simulation ◽  
Respiratory System ◽  
Limiting Factor ◽  
Respiratory System Compliance ◽  
Closing Time ◽  
Closed State ◽  
Occlusion Device ◽  
Tissue Resistance ◽  
Technical Properties

The interrupter technique is used to determine airway and tissue resistance. Their accuracy is influenced by the technical properties of the interrupter device and the compliance of the respiratory system. We investigated the influence of valve characteristics and respiratory system compliance on the accuracy of determining airway and tissue resistance by means of a computer simulation. With decreasing compliance we found increasing errors in both airway and tissue resistance determination of up to 34 and 71%, respectively. On this basis we developed a new occlusion valve, with special emphasis on rapid closing time and tightness in the closed state to improve the accuracy of resistance determination. The newly developed occlusion device greatly improves the accuracy of airway and tissue resistance determination. We conclude that respiratory system compliance is a limiting factor for the accuracy of the interrupter technique. To apply the interrupter technique in patients with extremely low respiratory system compliances, we need sophisticated technical devices.

P-257 Preneoplastic lesions in the respiratory system of chernobyl chronic bronchitis patients

Lung Cancer ◽  
2003 ◽  
Vol 41 ◽  
pp. S157
Author(s):  
Svetlana Yu. Chikina ◽  
Maria V. Samsonova ◽  
Andrey L. Chernyaev ◽  
Viktor V. Chizhikov ◽  
Alexander G. Chuchalin ◽  
...  
Keyword(s):  
Chronic Bronchitis ◽  
Respiratory System ◽  
Preneoplastic Lesions

Methods for determination of cell volume in tissue culture

1992 ◽  
Vol 70 (S1) ◽  
pp. S323-S333 ◽  
Author(s):  
H. K. Kimelberg ◽  
E. R. O'Connor ◽  
P. Sankar ◽  
C. Keese
Keyword(s):  
Tissue Culture ◽  
Cell Volume ◽  
Suspension Cultures ◽  
Coulter Counter ◽  
Dynamic Changes ◽  
Physical Methods ◽  
Monolayer Cultures ◽  
Primary Astrocyte

In this paper we present an overview of methods for determining cell volume in both suspension and monolayer cultures. Data from the use of selected methods such as the Coulter counter system for suspension cultures and radiolabelled intracellular markers for substratum-attached, monolayer cultures are presented. The advantages, limitations, and conditions under which the different methods can be used are discussed. It is pointed out that there is a need for more direct physical methods for measuring dynamic changes in the cell volume of monolayer cultures without removing the cells from the substratum. Data from a method applicable to such cultures that measures extracellular impedance are presented.Key words: cell volume, monolayer cultures, extracellular impedance, radiolabelled intracellular markers, primary astrocyte cultures.

Possible errors using esophageal balloon in determination of pressure-volume characteristics of the lung and thoracic cage

1959 ◽  
Vol 14 (4) ◽  
pp. 525-530 ◽  
Author(s):  
John H. Knowles ◽  
Suk Ki Hong ◽  
Hermann Rahn
Keyword(s):  
Respiratory System ◽  
Supine Position ◽  
Static Pressure ◽  
Thoracic Cage ◽  
Lung Volumes ◽  
Esophageal Balloon ◽  
Volume Characteristics

The static pressure-volume curves of the lung, thoracic cage and total respiratory system were studied in the sitting, supine, prone and knee-elbow position in four subjects. The lung and thoracic-cage pressures were measured with the aid of an esophageal balloon and recorded on a water manometer. The analysis of these various components suggests that in the supine position the esophageal balloon is compressed by the mediastinal content, giving rise to an artifact in the recording of the lung pressure. If this artifact is taken into consideration, it would appear that the effect of posture on the compliance of the lung is negligible. Lung pressures calculated for various lung volumes during active breathing are compared with static values recorded on a water manometer. Submitted on December 19, 1958

scholarly journals Determination of respiratory system compliance during pressure support ventilation by small variations of pressure support

2017 ◽  
Vol 32 (4) ◽  
pp. 741-751 ◽  
Author(s):  
Tobias Becher ◽  
Dirk Schädler ◽  
Philipp Rostalski ◽  
Günther Zick ◽  
Inéz Frerichs ◽  
...  
Keyword(s):  
Respiratory System ◽  
Pressure Support Ventilation ◽  
Pressure Support ◽  
Respiratory System Compliance ◽  
Support Ventilation
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