scholarly journals Data-Driven Sonification of CFD Aneurysm Models

2018 ◽  
Author(s):  
Daniel E. MacDonald ◽  
Thangam Natarajan ◽  
Richard C. Windeyer ◽  
Peter Coppin ◽  
David A. Steinman
Keyword(s):  
Fluid Dynamics ◽  
Blood Flow ◽  
Cerebral Aneurysms ◽  
Spatiotemporal Data ◽  
Data Driven ◽  
Flow Fluctuations ◽  
Novel Method ◽  
Computational Fluid Dynamics Cfd ◽  
Flow Visualizations ◽  
Blood Flow Patterns

A novel method is presented for inspecting and characterizing turbulent-like hemodynamic structures in intracranial cerebral aneurysms by sonification of data generated using Computational Fluid Dynamics (CFD). The intention of the current research is to intuitively communicate flow complexity by augmenting conventional flow visualizations with data-driven sound, thereby increasing the ease of interpretation of dense spatiotemporal data through multimodal presentation. The described implementation allows the user to listen to flow fluctuations thought to indicate turbulent-like blood flow patterns that are often visually difficult to discriminate in conventional flow visualizations.

CFD Study on Effect of Branch Sizes in Human Coronary Arteries

2011 ◽  
Author(s):  
Liza Shrestha ◽  
Justin Garvin ◽  
Richard W. Downe ◽  
Milan Sonka ◽  
Andreas Wahle ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Coronary Artery Disease ◽  
Blood Flow ◽  
Shear Stress ◽  
Causes Of Death ◽  
Developed Countries ◽  
Unidirectional Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Artery Disease ◽  
Blood Flow Patterns

Coronary Artery Disease (CAD) is one of the leading causes of death in developed countries. The link between Wall Shear Stress (WSS) and CAD development is well established, with studies indicating the accumulation of lesions in regions of low WSS, flow separation, and in the regions where there is departure from axially aligned unidirectional flow [5]. It has been well established that blood flow patterns are highly affected by branch flows, as bifurcations are one of the leading locations of plaque accumulation [5]. Computational fluid dynamics (CFD) is an important tool for quantifying hemodynamics.

scholarly journals A Workflow for Patient-Individualized Virtual Angiogram Generation Based on CFD Simulation

2012 ◽  
Vol 2012 ◽  
pp. 1-24 ◽  
Author(s):  
Jürgen Endres ◽  
Markus Kowarschik ◽  
Thomas Redel ◽  
Puneet Sharma ◽  
Viorel Mihalef ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Blood Flow ◽  
Shear Stress ◽  
Cfd Simulation ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Hemodynamic Parameters ◽  
Risk Of Rupture ◽  
Computational Fluid Dynamics Cfd ◽  
Subsequent Comparison

Increasing interest is drawn on hemodynamic parameters for classifying the risk of rupture as well as treatment planning of cerebral aneurysms. A proposed method to obtain quantities such as wall shear stress, pressure, and blood flow velocity is to numerically simulate the blood flow using computational fluid dynamics (CFD) methods. For the validation of those calculated quantities, virtually generated angiograms, based on the CFD results, are increasingly used for a subsequent comparison with real, acquired angiograms. For the generation of virtual angiograms, several patient-specific parameters have to be incorporated to obtain virtual angiograms which match the acquired angiograms as best as possible. For this purpose, a workflow is presented and demonstrated involving multiple phantom and patient cases.

scholarly journals Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

2021 ◽  
Vol 11 (4) ◽  
pp. 520
Author(s):  
Emily R. Nordahl ◽  
Susheil Uthamaraj ◽  
Kendall D. Dennis ◽  
Alena Sejkorová ◽  
Aleš Hejčl ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Kinetic Energy ◽  
Swirling Flow ◽  
Morphological Changes ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Aneurysm Wall ◽  
Aneurysm Growth ◽  
Computational Fluid Dynamics Cfd

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.

Computational Fluid Dynamics (CFD) Study of the 4th Generation Prototype of a Continuous Flow Ventricular Assist Device (VAD)

2004 ◽  
Vol 126 (2) ◽  
pp. 180-187 ◽  
Author(s):  
Xinwei Song ◽  
Houston G. Wood ◽  
Don Olsen
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Flow ◽  
Ventricular Assist Device ◽  
Continuous Flow ◽  
Surrounding Tissue ◽  
Assist Device ◽  
Ventricular Assist ◽  
Wide Range ◽  
Computational Fluid Dynamics Cfd

The continuous flow ventricular assist device (VAD) is a miniature centrifugal pump, fully suspended by magnetic bearings, which is being developed for implantation in humans. The CF4 model is the first actual prototype of the final design product. The overall performances of blood flow in CF4 have been simulated using computational fluid dynamics (CFD) software: CFX, which is commercially available from ANSYS Inc. The flow regions modeled in CF4 include the inlet elbow, the five-blade impeller, the clearance gap below the impeller, and the exit volute. According to different needs from patients, a wide range of flow rates and revolutions per minute (RPM) have been studied. The flow rate-pressure curves are given. The streamlines in the flow field are drawn to detect stagnation points and vortices that could lead to thrombosis. The stress is calculated in the fluid field to estimate potential hemolysis. The stress is elevated to the decreased size of the blood flow paths through the smaller pump, but is still within the safe range. The thermal study on the pump, the blood and the surrounding tissue shows the temperature rise due to magnetoelectric heat sources and thermal dissipation is insignificant. CFD simulation proved valuable to demonstrate and to improve the performance of fluid flow in the design of a small size pump.

scholarly journals Hemodynamic Consideration of Intracranial Aneurysm

2017 ◽  
Vol 3 (4) ◽  
pp. 229-236
Author(s):  
Hiroshi Ujiie ◽  
Chie Shinohara ◽  
Yoshinori Tamano ◽  
Kouichi Katou ◽  
Akira Teramoto
Keyword(s):  
Fluid Dynamics ◽  
Blood Flow ◽  
Intracranial Aneurysm ◽  
Middle Cerebral Artery ◽  
Internal Carotid ◽  
Cerebral Aneurysms ◽  
Anterior Communicating Artery ◽  
Great Care ◽  
Wall Strength ◽  
Surgical Manipulation

We reviewed basic considerations in fluid dynamics of cerebral aneurysms and applied these in surgery on the three most common types: internal carotid-posterior communicating artery, middle cerebral artery, and anterior communicating artery. It was found that aneurysmal initiation and growth do not occur at symmetric bifurcations. As blood flow always obeys the law of inertia, jet flow into the aneurysm will disperse along the wall; assuming the aneurysmal wall strength is even, the shape of the aneurysm becomes round or oval. When neurosurgeons encounter an aneurysm that is not round or oval, the wall may be fragile and requires great care during surgical manipulation.

scholarly journals Numerical Analysis of Blood Flow Through Discrete Stenosis: Role of Eccentricity and Spacing Ratio

2017 ◽  
Author(s):  
Siyeong Ju ◽  
Linxia Gu
Keyword(s):  
Fluid Dynamics ◽  
Blood Flow ◽  
Recirculation Zone ◽  
Cfd Simulation ◽  
Flow Region ◽  
Flow Recirculation ◽  
Spacing Ratio ◽  
Computational Fluid Dynamics Cfd ◽  
Flow Interference

Stenosis or narrowing of arteries induces a turbulent flow region downstream. Multiple stenosis may lead to flow interference and further disturb the blood flow. This has important clinical implications [1], such as disturbed blood flow and flow recirculation which were correlated with the development of atherosclerosis by upregulating the endothelial cells genes and proteins that cause atherogenesis [2]. Numerical simulation of concentric stenoses by Lee et al [3] have shown that the recirculation zone following the first concentric stenosis affected the flow field at the downstream of the second one, which was dependent on the spacing ratio and degree of stenosis. However, the majority of stenosis is eccentric [2] and the detailed fluid dynamics of multiple stenoses with eccentric constrictions is lacking. The aim of this study is to investigate the interactions between double stenoses with eccentricity using computational fluid dynamics (CFD) simulation. The role of spacing ratio on the recirculation zone and turbulence intensity (TI) were characterized and also compared to concentric cases.

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