scholarly journals 34. Experimental Studies on Peripheral Nerve Regeneration

1963 ◽  
Vol 5 (0) ◽  
pp. 66-67
Author(s):  
Shigeo UEDA ◽  
Yuri INAZUMI ◽  
Yoshihiro KAWAMURA
Keyword(s):  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Experimental Studies

scholarly journals Photobiomodulation in Sciatic Nerve Crush Injuries in Rodents: A Systematic Review of the Literature and Perspectives for Clinical Treatment

2020 ◽  
Vol 11 (3) ◽  
pp. 332-344
Author(s):  
Letícia Lemes Sasso ◽  
Luana Gabriel de Souza ◽  
Carlos Eduardo Girasol ◽  
Alexandre Márcio Marcolino ◽  
Rinaldo Roberto de Jesus Guirro ◽  
...  
Keyword(s):  
Energy Density ◽  
Sciatic Nerve ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Experimental Studies ◽  
Therapeutic Window ◽  
Sciatic Nerve Crush ◽  
Nerve Crush ◽  
Positive Effects

Objective: The aim of the study was to perform a literature review to analyze the effect of photobiomodulation in experimental studies on peripheral nerve regeneration after sciatic nerve crush injury in rodents. Methods: A bibliographic search was performed in the electronic databases, including MEDLINE (PubMed), SCOPUS, and SciELO, from 2008 to 2018. Results: A total of 1912 articles were identified in the search, and only 19 fulfilled all the inclusion criteria. Along with the parameters most found in the manuscripts, the most used wavelengths were 660 nm and 830 nm, power of 30 and 40 mW, and energy density of 4 and 10 J/cm2 . For total energy throughout the intervention period, the lowest energy found with positive effects was 0.70 J, and the highest 1.141 J. Seventeen studies reported positive effects on nerve regeneration. The variables selected to analyze the effect were: Sciatic Functional Index (SFI), Static Sciatic Index (SSI), morphometric, morphological, histological, zymographic, electrophysiological, resistance mechanics and range of motion (ROM). The variety of parameters used in the studies demonstrated that there is yet no pre-determined protocol for treating peripheral nerve regeneration. Only two studies by different authors used the same power, energy density, beam area, and power density. Conclusion: It was concluded that the therapeutic window of the photobiomodulation presents a high variability of parameters with the wavelength (632.8 to 940 nm), power (5 to 170 mW) and energy density (3 to 280 J /cm2 ), promoting nerve regeneration through the expression of cytokines and growth factors that aid in modulating the inflammatory process, improving morphological aspects, restoring the functionality to the animals in a brief period.

Experimental studies on peripheral nerve regeneration enhanced by nerve growth factor

1993 ◽  
Vol 13 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Pang Qing-jiang ◽  
Luo Yong-xiang ◽  
Wu Yang-guan ◽  
Li Zhen-fan ◽  
Fang Huang ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Experimental Studies ◽  
Nerve Growth

Modern approaches to peripheral nerve regeneration after injury: the prospects of gene and cell therapy

2017 ◽  
Author(s):  
M. Karagyaur ◽  
P. Makarevich ◽  
E. Shevchenko ◽  
D. Stambolsky ◽  
N. Kalinina ◽  
...  
Keyword(s):  
Cell Therapy ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Gene And Cell Therapy

Oxidized Galectin-1 is an Essential Factor for Peripheral Nerve Regeneration

2005 ◽  
Vol 6 (4) ◽  
pp. 385-394 ◽  
Author(s):  
Hidenori Horie ◽  
Toshihiko Kadoya ◽  
Kazunori Sango ◽  
Mitsuhiro Hasegawa
Keyword(s):  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Essential Factor
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