scholarly journals Glioblastoma Multiforme in the Left Frontal Lobe Subsequent to Malignant Lymphoma in the Right Orbit —Case Report—

1996 ◽  
Vol 36 (1) ◽  
pp. 11-14 ◽  
Author(s):  
Mamoru TOMIDA ◽  
Masaaki MURAKI ◽  
Hisaya HIRAMATSU ◽  
Katsuyuki TSUKAMOTO ◽  
Kaoru HINOKUMA ◽  
...  
2021 ◽  
Vol 8 (2) ◽  
pp. 1620-1626
Author(s):  
Jiafeng Yu ◽  
Xin Zhao ◽  
Yingfeng Liu ◽  
Qingwei Yan ◽  
Fei Miao

Pulse ◽  
2017 ◽  
Vol 9 (1) ◽  
pp. 45-48
Author(s):  
MR Molla ◽  
F Ferdousi ◽  
DR Shankar ◽  
AKMB Karim

A 13 years old boy admitted with the complaint of progressive exophthalmos and gradually decreasing vision on right eye, also occasional headache and deformity on the right fronto-orbital region. Radiological & clinical findings revealed a case of frontal osteoma in the right frontal sinus extending up to right frontal lobe, eroding right roof of the orbit. Complete excision of the tumor mass was possible surgically. Biopsy confirmed a case of osteoma. Below is a discussion on diagnosis & management of frontal osteomaPulse Vol.9 January-December 2016 p.45-48


2013 ◽  
Vol 17 (3) ◽  
pp. 162-165
Author(s):  
Cathlyn Niranjana Bennett ◽  
Jamuna Rajeswaran ◽  
S. Sampath ◽  
Rita Christopher

1991 ◽  
Vol 4 (3) ◽  
pp. 167-179 ◽  
Author(s):  
Alan J. Parkin ◽  
Caroline Barry

We describe a right-handed patient who suffered a ruptured aneurysm of the anterior communicating artery (ACoA) which was clipped successfully. Computerized tomography indicated a low density area in the genu of the corpus callosum and the infero-lateral aspect of the left frontal lobe. On recovery the patient's most notable deficit was the “alien hand sign” whereby the left hand would frequently interfere with the actions of the right hand. Problems in response initiation were also evident. There was significant memory loss and performance was impaired on some tests of frontal lobe function. Discussion centres on the functional locus of the alien hand sign but other aspects of the patient's deficits are also considered.


2011 ◽  
Vol 22 (2) ◽  
pp. 404-406 ◽  
Author(s):  
Rei Enatsu ◽  
Stephen Hantus ◽  
Jorge Gonzalez-Martinez ◽  
Norman So

2012 ◽  
Vol 30 (4) ◽  
pp. 307-315 ◽  
Author(s):  
Yu Zheng ◽  
Shanshan Qu ◽  
Na Wang ◽  
Limin Liu ◽  
Guanzhong Zhang ◽  
...  

Objective The aim of the present work was to observe the activation/deactivation of cerebral functional regions after electroacupuncture (EA) at Yintang (EX-HN3) and GV20 by functional MRI (fMRI). Design A total of 12 healthy volunteers were stimulated by EA at Yintang and GV20 for 30 min. Resting-state fMRI scans were performed before EA, and at 5 and 15 min after needle removal. Statistical parametric mapping was used to preprocess initial data, and regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) were analysed. Results ReHo at 5 min post stimulation showed increases in the left temporal lobe and cerebellum and decreases in the left parietal lobe, occipital lobe and right precuneus. At 15 min post stimulation, ReHo showed increases in the left fusiform gyrus; lingual gyrus; middle temporal gyrus; postcentral gyrus; limbic lobe; cingulate gyrus; paracentral lobule; cerebellum, posterior lobe, declive; right cuneus and cerebellum, anterior lobe, culmen. It also showed decreases in the left frontal lobe, parietal lobe, right temporal lobe, frontal lobe, parietal lobe and right cingulate gyrus. ALFF at 5 min post stimulation showed increases in the right temporal lobe, but decreases in the right limbic lobe and posterior cingulate gyrus. At 15 min post stimulation ALFF showed increases in the left frontal lobe, parietal lobe, occipital lobe, right temporal lobe, parietal lobe, occipital lobe and cerebellum, but decreases in the left frontal lobe, anterior cingulate gyrus, right frontal lobe and posterior cingulate gyrus. Conclusions After EA stimulation at Yintang and GV20, which are associated with psychiatric disorder treatments, changes were localised in the frontal lobe, cingulate gyrus and cerebellum. Changes were higher in number and intensity at 15 min than at 5 min after needle removal, demonstrating lasting and strong after-effects of EA on cerebral functional regions.


Author(s):  
Joyce JG ◽  
O’Dowd M ◽  
Ryan RS ◽  
Stokes HS ◽  
ONeill MB

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi99-vi99
Author(s):  
Kyu Sang Lee ◽  
Gheeyoung Choe

Abstract Primary glioblastoma develops de novo without clinical or histological evidence of a low-grade precursor lesion, while secondary glioblastoma develops from a low-grade glioma. The same IDH mutation is observed in almost secondary glioblastomas that occurs in low-grade gliomas with IDH mutation. Present report is an extraordinary case of secondary glioblastoma, IDH-wildtype arising in diffuse astrocytoma, IDH-mutant. A 31-year-old female presented with seizure 3 months ago, who had a history of operation for diffuse astrocytoma, IDH-mutant on the left frontal lobe 6 years ago. Magnetic resonance imaging test revealed new infiltrative lesions (6.5cm) in left frontal lobe and corpus callosum, in addition to the non-enhancing mass (3.4cm). New infiltrative lesion suspected anaplastic change and the patient underwent tumorectomy. Microscopically, non-enhancing lesion showed high cellularity, moderate nuclear atypia and brisk mitosis. Microvascular proliferation and necrosis were absent that can be diagnosis as anaplastic astrocytoma. However, new infiltrative lesion showed microvascular proliferation and necrosis that acceptable for diagnosis as glioblastoma. IDH-1 immunohistochemistry (IHC) was positive in anaplastic astrocytoma but negative in glioblastoma. In addition, we assessed NGS based on the SNUBH Brain v1.0 (Macrogen, Seoul, South Korea) panel. Similar to IHC result, IDH-1 (p.Arg132His) mutation was found in anaplastic astrocytoma but not in glioblastoma. Interestingly, ATRX (p.Gln1670Ter) and TP53 (p.His193Arg) mutations were found in both lesions. Additionally, PTEN (p.His296Pro) mutation was identified in glioblastoma component only. Until now, it is well-known hypothesis that the IDH mutation initiated in glial progenitor cell and the other genetic mutations occur sequentially in pathogenesis of secondary glioblastoma. Notably, this is the first case report that other genetic alterations can be initiated before IDH mutation contrary to previous hypothesis. In our case, mutation of ATRX and TP53 might be initiated, and PTEN and IDH-1 mutations were sequentially occurred in glioblastoma and anaplastic astrocytoma, respectively.


The study of patients undergoing unilateral frontal-lobe excisions for the relief of focal epilepsy has revealed specific cognitive disorders that appear against a background of normal functioning on many intellectual, perceptual and memory tasks. Lesions that invade the frontal eye field cause subtle impairments of voluntary oculomotor control, which reveal themselves as an inability to suppress an initial glance at a potentially distracting stimulus. After frontal lobectomy in either hemisphere, deficits are found quite consistently on motor-differentiation tasks (Konorski 1972) in which the subject must learn to produce different responses to different, randomly presented, environmental signals. More directly related to the concept of planning are those sequential tasks in which the subject is free to choose his own order of responding, but must not make the same response twice. Here the left frontal lobe plays the major role, a finding consistent with the notion of left-hemisphere dominance for the programming of voluntary actions. In contrast, the right frontal lobe appears to be more critically involved in monitoring the temporal sequence of externally ordered events, although the verbal or non-verbal nature of the stimuli remains a relevant factor.


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