scholarly journals Characterization of the molecular structure and mechanical properties of polymer surfaces and protein/polymer interfaces by sum frequency generation vibrational spectroscopy and atomic force microscopy

2004 ◽  
Author(s):  
Telly Stelianos Koffas
Materialia ◽  
2021 ◽  
Vol 16 ◽  
pp. 101074
Author(s):  
Fereshteh Jafarbeglou ◽  
Mohammad Ali Nazari ◽  
Fatemeh Keikha ◽  
Saeid Amanpour ◽  
Mojtaba Azadi

2018 ◽  
Vol 12 (4) ◽  
Author(s):  
Tariq Mohana Bahwini ◽  
Yongmin Zhong ◽  
Chengfan Gu ◽  
Zeyad Nasa ◽  
Denny Oetomo

Characterization of cell mechanical properties plays an important role in disease diagnoses and treatments. This paper uses advanced atomic force microscopy (AFM) to measure the geometrical and mechanical properties of two different human brain normal HNC-2 and cancer U87 MG cells. Based on experimental measurement, it measures the cell deformation and indentation force to characterize cell mechanical properties. A fitting algorithm is developed to generate the force-loading curves from experimental data. An inverse Hertzian method is also established to identify Young's moduli for HNC-2 and U87 MG cells. The results demonstrate that Young's modulus of cancer cells is different from that of normal cells, which can help us to differentiate normal and cancer cells from the biomechanical viewpoint.


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