scholarly journals Biosynthesis of long-chain dicarboxylic acid monomers from renewable resources. Final technical report

1999 ◽  
Author(s):  
David P. Mobley
Keyword(s):  
Dicarboxylic Acid ◽  
Renewable Resources ◽  
Technical Report ◽  
Long Chain

scholarly journals Reduced Plasma Levels of Very-Long-Chain Dicarboxylic Acid 28:4 in Italian and Brazilian Colorectal Cancer Patient Cohorts

Metabolites ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 91 ◽  
Author(s):  
Paul Wood ◽  
Michelle Donohue ◽  
John Cebak ◽  
Taylor Beckmann ◽  
Márcia Messias ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dicarboxylic Acid ◽  
Cancer Patients ◽  
Plasma Levels ◽  
High Resolution Mass Spectrometry ◽  
Sporadic Colorectal Cancer ◽  
Inherited Susceptibility ◽  
Potential Biomarker ◽  
Colorectal Cancer Patients ◽  
Long Chain

Background: There are currently no blood-based biomarkers for early diagnosis of colorectal cancer. Previous research has suggested that very-long-chain dicarboxylic acid (VLCDCA) 28:4 might be such a biomarker. Methods: Using high-resolution mass spectrometry, we analyzed VLCDCA 28:4 in the plasma of colorectal cancer patients in Italian [n = 62] and Brazilian [n = 52] cohorts. Additionally, we investigated individuals diagnosed with familial adenomatous polyposis (FAP; n = 27), one of the most important clinical forms of inherited susceptibility to colorectal cancer. Results: Decrements in plasma levels of VLCDCA 28:4 were monitored in colorectal cancer patients. These decreases were independent of the stage of tumor development and the individual’s age. However, no decrements in VLCDCA 28:4 were monitored in FAP patients. Conclusions: The plasma levels of VLCDCA 28:4 represent a potential biomarker of sporadic colorectal cancer. In addition, it is possible that resupply of this anti-inflammatory lipid may represent a new therapeutic strategy for CRC and inflammatory disorders.

Secretion in long-chain dicarboxylic acid fermentation

2000 ◽  
Vol 22 (5) ◽  
pp. 391-396 ◽  
Author(s):  
R. Lin ◽  
Z. Cao ◽  
T. Zhu ◽  
Z. Zhang
Keyword(s):  
Dicarboxylic Acid ◽  
Acid Fermentation ◽  
Long Chain

Intermediary metabolism of Acinetobacter grown on dialkyl ethers

1989 ◽  
Vol 35 (11) ◽  
pp. 1031-1036 ◽  
Author(s):  
Malcolm C. Modrzakowski ◽  
William R. Finnerty
Keyword(s):  
Fatty Acids ◽  
Dicarboxylic Acid ◽  
Chain Length ◽  
Dicarboxylic Acids ◽  
Acid Oxidation ◽  
Methyl Group ◽  
Ether Oxygen ◽  
Dialkyl Ethers ◽  
Long Chain ◽  
Methyl Group Oxidation

The microbial dissimilation of long-chain dialkyl ethers by Acinetobacter sp. H01-N involved a terminal methyl group oxidation of the dialkyl ether substrates, resulting in the formation of ether oxygen containing fatty acids of corresponding chain length. An internal carbon–carbon scission of the dialkyl ethers resulted in the formation of end-product ether fatty acids and corresponding dicarboxylic acids. Cellular carbon and energy were derived from the subsequent metabolism of the dicarboxylic acids. Dicarboxylic acid oxidation, activation, and identification of cellular dicarboxylic acids indicated dibasic acids as intermediates in the metabolism of dialkyl ethers.Key words: dialkyl ethers, dicarboxylic acids, fatty acids, Acinetobacter.

scholarly journals Thermoplastic polyester elastomers based on long-chain crystallizable aliphatic hard segments

2015 ◽  
Vol 6 (40) ◽  
pp. 7133-7137 ◽  
Author(s):  
Florian Stempfle ◽  
Brigitta Schemmer ◽  
Anna-Lena Oechsle ◽  
Stefan Mecking
Keyword(s):  
Dicarboxylic Acid ◽  
Plant Oil ◽  
Hard Segments ◽  
Long Chain

Thermoplastic polyester elastomers prepared from a plant-oil derived crystallizable long-chain aliphatic α,ω-dicarboxylic acid have been investigated.

scholarly journals Synthesis of copolyesters with bio-based lauric diacid: structure and physico-mechanical studies

RSC Advances ◽  
2017 ◽  
Vol 7 (87) ◽  
pp. 55418-55426 ◽  
Author(s):  
Meiling Chen ◽  
Nesren A. H. Saada ◽  
Fei Liu ◽  
Haining Na ◽  
Jin Zhu
Keyword(s):  
Mechanical Properties ◽  
Dicarboxylic Acid ◽  
Biodegradable Materials ◽  
Long Chain ◽  
Mechanical Studies

Copolyesters developed from bio-based long-chain dicarboxylic acid show promising mechanical properties that are helpful for their application as biodegradable materials.

scholarly journals CYP86B1 Is Required for Very Long Chain ω-Hydroxyacid and α,ω-Dicarboxylic Acid Synthesis in Root and Seed Suberin Polyester

2009 ◽  
Vol 150 (4) ◽  
pp. 1831-1843 ◽  
Author(s):  
Vincent Compagnon ◽  
Patrik Diehl ◽  
Irène Benveniste ◽  
Denise Meyer ◽  
Hubert Schaller ◽  
...  
Keyword(s):  
Dicarboxylic Acid ◽  
Acid Synthesis ◽  
Long Chain
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