Planner Individual Project: Hybrid Planner - Final Draft

Flow cytometry remains a commonly used methodology due to its ability to characterise multiple parameters on single particles in a high-throughput manner. In order to address limitations with lacking sensitivity of conventional flow cytometry to characterise extracellular vesicles (EVs), novel, highly sensitive platforms, such as high-resolution and imaging flow cytometers, have been developed. We provided comparative benchmarks of a conventional FACS Aria III, a high-resolution Apogee A60 Micro-PLUS and the ImageStream X Mk II imaging flow cytometry platform. Nanospheres were used to systematically characterise the abilities of each platform to detect and quantify populations with different sizes, refractive indices and fluorescence properties, and the repeatability in concentration determinations was reported for each population. We evaluated the ability of the three platforms to detect different EV phenotypes in blood plasma and the intra-day, inter-day and global variabilities in determining EV concentrations. By applying this or similar methodology to characterise methods, researchers would be able to make informed decisions on choice of platforms and thereby be able to match suitable flow cytometry platforms with projects based on the needs of each individual project. This would greatly contribute to improving the robustness and reproducibility of EV studies.

Download Full-text

Professor George H. Dession's Final Draft of the Code of Correction for Puerto Rico

The Yale Law Journal ◽

10.2307/794393 ◽

1962 ◽

Vol 71 (6) ◽

pp. 1050

Keyword(s):

Puerto Rico ◽

Final Draft

Download Full-text

HERODOTUS BECOMES INTERESTED IN HISTORY

Greece and Rome ◽

10.1017/s001738351300020x ◽

2014 ◽

Vol 61 (1) ◽

pp. 1-6

Author(s):

David Harvey

Keyword(s):

Major Part ◽

The Real ◽

Final Draft ◽

First Time ◽

The Temple ◽

Greek World ◽

The Way

At 3.60 Herodotus tells us that he has dwelt at length on the Samians because ‘they are responsible for three of the greatest buildings in the Greek world’: the tunnel of Eupalinos, the great temple, and the breakwater that protects their harbour. As successive commentators have pointed out, that is not the real reason for the length of his account. We hear about the tunnel for the first time in this chapter (60.1–3); Maiandrios escapes down a secret channel at 146.2, which may or may not be Eupalinos' tunnel; we hear about the temple of Artemis, not of Hera, at Samos in 48; dedications in the temple of Hera are mentioned in passing at 1.70.3, 3.123.1, 4.88.1, and 4.152.4, but the temple itself cannot be said to play a major part in Herodotus' narrative; naval expeditions sail from Samos (e.g. 44.2, 59.4) but there is no emphasis on the harbour or its breakwater. What Herodotus should have said is ‘I have dwelt at length on Samos, because I am interested in the island's history; and, by the way, they are responsible for three…’; but it is not our job to tell him what he ‘should’ have said. As David Asheri remarks, ‘We can explain it [the length of the Samian logos] most simply by supposing that the logos already existed before the final draft of the book’.

Download Full-text

KNOWLEDGE DYNAMICS IN FRAGMENTED INDUSTRIES

International Journal of Innovation and Technology Management ◽

10.1142/s0219877014500047 ◽

2014 ◽

Vol 11 (02) ◽

pp. 1450004

Author(s):

FEDERICA CECI ◽

DAJANA D'ANDREA

Keyword(s):

Organizational Learning ◽

Project Based Learning ◽

Media Content ◽

Economic Activities ◽

Individual Project ◽

Comprehensive Picture ◽

Knowledge Dynamics ◽

Systematic Understanding ◽

The Uk ◽

Over Time

This paper aims to provide a comprehensive picture of knowledge dynamics in fragmented industries in which economic activities are performed through inter-firm projects. The organization performing the project often does not survive the project itself, though knowledge is acquired and retained over time and across the whole industry. Notwithstanding scholars' interest, a systematic understanding of this subject is still lacking. To fill this gap, an analytical model has been developed to describe the processes of knowledge acquisition and retention in fragmented industries. Drawing upon empirical evidence collected from the UK media content industry and literature on project-based learning, project-based organization and organizational learning, the model presents the variables involved in these processes, distinguishing them according to the level at which they act (individual, project, industry) and according to the role they play (process or moderator). Implications for practitioners and policymakers are then discussed.

Download Full-text