Form development sample test matrix

1999 ◽  
Author(s):  
B B Ebbinghaus
2018 ◽  
Vol 4 (4) ◽  
pp. 523-531
Author(s):  
Hina Mumtaz ◽  
Muhammad Asim Farooq ◽  
Zainab Batool ◽  
Anam Ahsan ◽  
Ashikujaman Syed

The main purpose of development pharmaceutical dosage form is to find out the in vivo and in vitro behavior of dosage form. This challenge is overcome by implementation of in-vivo and in-vitro correlation. Application of this technique is economical and time saving in dosage form development. It shortens the period of development dosage form as well as improves product quality. IVIVC reduce the experimental study on human because IVIVC involves the in vivo relevant media utilization in vitro specifications. The key goal of IVIVC is to serve as alternate for in vivo bioavailability studies and serve as justification for bio waivers. IVIVC follows the specifications and relevant quality control parameters that lead to improvement in pharmaceutical dosage form development in short period of time. Recently in-vivo in-vitro correlation (IVIVC) has found application to predict the pharmacokinetic behaviour of pharmaceutical preparations. It has emerged as a reliable tool to find the mode of absorption of several dosage forms. It is used to correlate the in-vitro dissolution with in vivo pharmacokinetic profile. IVIVC made use to predict the bioavailability of the drug of particular dosage form. IVIVC is satisfactory for the therapeutic release profile specifications of the formulation. IVIVC model has capability to predict plasma drug concentration from in vitro dissolution media.


2018 ◽  
Vol 1 ◽  
pp. 107
Author(s):  
Adi Heryadi ◽  
Evianawati Evianawati

This study aims to prove whether transformational leadership training is effective for building anti-corruption attitudes of villages in Kebonharjo village, subdistrict Samigaluh Kulonprogo. This research is an experimental research with one group pre and posttest design.Subject design is 17 people from village of 21 candidates registered. Measuring tool used in this research is the scale of anti-corruption perception made by the researcher referring to the 9 anti-corruption values with the value of reliability coefficient of 0.871. The module used as an intervention made by the researcher refers to the transformational leadership dimension (Bass, 1990). The data collected is analyzed by statistical analysis of different test Paired Sample Test. Initial data collection results obtained sign value of 0.770 which means> 0.05 or no significant difference between anti-corruption perception score between before and after training. After a period of less than 1 (one) month then conducted again the measurement of follow-up of the study subjects in the measurement again using the scale of anti-corruption perception. The results of the second data collection were analysed with Paired Samples Test and obtained the value of 0.623 sign meaning p> 0.05 or no significant difference between post test data with follow-up data so that the hypothesis of this study was rejected.


1986 ◽  
Author(s):  
Ronnie Warm ◽  
J. T. Roth ◽  
J. A. Fitzpatrick

2021 ◽  
Vol 5 (1) ◽  
pp. 10
Author(s):  
Mark Levene

A bootstrap-based hypothesis test of the goodness-of-fit for the marginal distribution of a time series is presented. Two metrics, the empirical survival Jensen–Shannon divergence (ESJS) and the Kolmogorov–Smirnov two-sample test statistic (KS2), are compared on four data sets—three stablecoin time series and a Bitcoin time series. We demonstrate that, after applying first-order differencing, all the data sets fit heavy-tailed α-stable distributions with 1<α<2 at the 95% confidence level. Moreover, ESJS is more powerful than KS2 on these data sets, since the widths of the derived confidence intervals for KS2 are, proportionately, much larger than those of ESJS.


1973 ◽  
Vol 8 (2) ◽  
pp. 22-23 ◽  
Author(s):  
Gerhard Zielke
Keyword(s):  

1990 ◽  
Vol 33 (3) ◽  
pp. 337-366 ◽  
Author(s):  
Harry Dym ◽  
Nicholas Young

Let N(λ) be a square matrix polynomial, and suppose det N is a polynomial of degree d. Subject to a certain non-singularity condition we construct a d by d Hermitian matrix whose signature determines the numbers of zeros of N inside and outside the unit circle. The result generalises a well known theorem of Schur and Cohn for scalar polynomials. The Hermitian “test matrix” is obtained as the inverse of the Gram matrix of a natural basis in a certain Krein space of rational vector functions associated with N. More complete results in a somewhat different formulation have been obtained by Lerer and Tismenetsky by other methods.


2019 ◽  
Vol 11 (20) ◽  
pp. 5850 ◽  
Author(s):  
Henryk Wojtaszek ◽  
Ireneusz Miciuła

This paper analyzes the actions that improve innovativeness in production enterprises in the Silesian province. Innovation is one of the elements that allows to achieve a competitive advantage. It is justified to research various factors that are important in improving innovativeness. The research includes selected production enterprises in the Silesian province, adopting the descriptive statistics measures and statistic tests: random sample test, chi-square independence test and the non-parametric Kruskal-Wallis test based on a survey questionnaire. Some of the most important factors determining the possibilities of innovation by manufacturing companies were detected contacts with other enterprises, R&D centers and counseling institutions, competitive position of the company, and creating appropriate incentive systems.


Author(s):  
Qi D. Van Eikema Hommes

As the content and variety of technology increases in automobiles, the complexity of the system increases as well. Decomposing systems into modules is one of the ways to manage and reduce system complexity. This paper surveys and compares a number of state-of-art components modularity metrics, using 8 sample test systems. The metrics include Whitney Index (WI), Change Cost (CC), Singular value Modularity Index (SMI), Visibility-Dependency (VD) plot, and social network centrality measures (degree, distance, bridging). The investigation reveals that WI and CC form a good pair of metrics that can be used to assess component modularity of a system. The social network centrality metrics are useful in identifying areas of architecture improvements for a system. These metrics were further applied to two actual vehicle embedded software systems. The first system is going through an architecture transformation. The metrics from the old system revealed the need for the improvements. The second system was recently architected, and the metrics values showed the quality of the architecture as well as areas for further improvements.


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