scholarly journals SOIL ME! Soil activation estimates for the g-2 target area and beam dump

1989 ◽  
Author(s):  
D. Beavis
2018 ◽  
Vol 24 (1) ◽  
Author(s):  
SHVETA PATEL ◽  
RAJENDRA SINGH

Extensive survey of mantids in the northeastern Uttar Pradesh was conducted. Two mantid species were recorded for the first time from the target area, viz.: Pyrgomantis pallida, 1917 and Bactromantis mexicana.


2016 ◽  
Vol 5 (2) ◽  
pp. 83-91
Author(s):  
Miftafu Darussalam ◽  
Dwi Kartika Rukmi

Background: Uric acid is a final product or a waste that is resulted from the metabolism of purines. A high level of uric acid (hyperuricemia) will cause several health problems, such as vascular inflammation, smooth muscle proliferation, and vascular lesion in kidneys. The syzygium polyanthum leaves contain bioactive substances that may affect the level of uric acid in blood. Objective: This study aimed to determine the influence of boiled water of syzygium polyanthum leaves to the changes of uric acid levels in the target area of Puskesmas Pandak 1 Bantul. Methods: This study employed pre- and post-test without control group design. The population consisted of all patients with hyperuricemia in the target area of Puskesmas Pandak 1 Bantul. Sample was selected with a concecutive sampling, gaining a total number of 24 respondents. Data were analyzed with the Wilcoxon test. The dose of boiled water of syzygium polyanthum leaves intake was 0.36g/ KgBW, once a day for 14 days. Result: This research showed that the boiled water of syzygium polyanthum leaves decreased hyperuricemia (uric acid levels), along with the significancy value of 0.009 (p <0.05). At the pre-test time, the average level of uric acid reached 7.279 mg/dl, and after the treatment, it decreased to 6.76 mg/dl. Conclusion: This study has established evidence that the boiled water of syzygium polyanthum leaves is able to decrease hyperuricemia (uric acid level in blood). Keywords: syzygium polyanthum, boiled water of syzygium polyanthum leaves, hyperuricemia


2019 ◽  
Vol 99 (7) ◽  
Author(s):  
Anthony Fradette ◽  
Maxim Pospelov ◽  
Josef Pradler ◽  
Adam Ritz
Keyword(s):  

2021 ◽  
Vol 22 (8) ◽  
pp. 4087
Author(s):  
Maria Quitério ◽  
Sandra Simões ◽  
Andreia Ascenso ◽  
Manuela Carvalheiro ◽  
Ana Paula Leandro ◽  
...  

Insulin is a peptide hormone with many physiological functions, besides its use in diabetes treatment. An important role of insulin is related to the wound healing process—however, insulin itself is too sensitive to the external environment requiring the protective of a nanocarrier. Polymer-based nanoparticles can protect, deliver, and retain the protein in the target area. This study aims to produce and characterize a topical treatment for wound healing consisting of insulin-loaded poly-DL-lactide/glycolide (PLGA) nanoparticles. Insulin-loaded nanoparticles present a mean size of approximately 500 nm and neutral surface charge. Spherical shaped nanoparticles are observed by scanning electron microscopy and confirmed by atomic force microscopy. SDS-PAGE and circular dichroism analysis demonstrated that insulin preserved its integrity and secondary structure after the encapsulation process. In vitro release studies suggested a controlled release profile. Safety of the formulation was confirmed using cell lines, and cell viability was concentration and time-dependent. Preliminary safety in vivo assays also revealed promising results.


2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Matthew J. Dolan ◽  
Torben Ferber ◽  
Christopher Hearty ◽  
Felix Kahlhoefer ◽  
Kai Schmidt-Hoberg

A mistake has been found in the numerical code used to reproduce the bounds from proton beam dump experiments from ref. [1] in figures 2 and 7 of ref. [2]. Correcting this mistake leads to slightly stronger bounds as shown below. We note that this correction does not include recent improvements in the analysis of proton beam dump experiments [3]. Additional recent bounds on GeV-scale ALPs can be found in refs. [4–8].


Author(s):  
Simona Malaspina ◽  
Vesa Oikonen ◽  
Anna Kuisma ◽  
Otto Ettala ◽  
Kalle Mattila ◽  
...  

Abstract Purpose This phase 1 open-label study evaluated the uptake kinetics of a novel theranostic PET radiopharmaceutical, 18F-rhPSMA-7.3, to optimise its use for imaging of prostate cancer. Methods Nine men, three with high-risk localised prostate cancer, three with treatment-naïve hormone-sensitive metastatic disease and three with castration-resistant metastatic disease, underwent dynamic 45-min PET scanning of a target area immediately post-injection of 300 MBq 18F-rhPSMA-7.3, followed by two whole-body PET/CT scans acquired from 60 and 90 min post-injection. Volumes of interest (VoIs) corresponding to prostate cancer lesions and reference tissues were recorded. Standardised uptake values (SUV) and lesion-to-reference ratios were calculated for 3 time frames: 35–45, 60–88 and 90–118 min. Net influx rates (Ki) were calculated using Patlak plots. Results Altogether, 44 lesions from the target area were identified. Optimal visual lesion detection started 60 min post-injection. The 18F-rhPSMA-7.3 signal from prostate cancer lesions increased over time, while reference tissue signals remained stable or decreased. The mean (SD) SUV (g/mL) at the 3 time frames were 8.4 (5.6), 10.1 (7) and 10.6 (7.5), respectively, for prostate lesions, 11.2 (4.3), 13 (4.8) and 14 (5.2) for lymph node metastases, and 4.6 (2.6), 5.7 (3.1) and 6.4 (3.5) for bone metastases. The mean (SD) lesion-to-reference ratio increases from the earliest to the 2 later time frames were 40% (10) and 59% (9), respectively, for the prostate, 65% (27) and 125% (47) for metastatic lymph nodes and 25% (19) and 32% (30) for bone lesions. Patlak plots from lesion VoIs signified almost irreversible uptake kinetics. Ki, SUV and lesion-to-reference ratio estimates showed good agreement. Conclusion 18F-rhPSMA-7.3 uptake in prostate cancer lesions was high. Lesion-to-background ratios increased over time, with optimal visual detection starting from 60 min post-injection. Thus, 18F-rhPSMA-7.3 emerges as a very promising PET radiopharmaceutical for diagnostic imaging of prostate cancer. Trial Registration NCT03995888 (24 June 2019).


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Chiaki Yamada ◽  
Aiko Maeda ◽  
Katsuyuki Matsushita ◽  
Shoko Nakayama ◽  
Kazuhiro Shirozu ◽  
...  

Abstract Background Patients with spinal cord injury (SCI) frequently complain of intractable pain that is resistant to conservative treatments. Here, we report the successful application of 1-kHz high-frequency spinal cord stimulation (SCS) in a patient with refractory neuropathic pain secondary to SCI. Case presentation A 69-year-old male diagnosed with SCI (C4 American Spinal Injury Association Impairment Scale A) presented with severe at-level bilateral upper extremity neuropathic pain. Temporary improvement in his symptoms with a nerve block implied peripheral component involvement. The patient received SCS, and though the tip of the leads could not reach the cervical vertebrae, a 1-kHz frequency stimulus relieved the intractable pain. Conclusions SCI-related symptoms may include peripheral components; SCS may have a considerable effect on intractable pain. Even when the SCS electrode lead cannot be positioned in the target area, 1-kHz high-frequency SCS may still produce positive effects.


2021 ◽  
Vol 2021 (8) ◽  
Author(s):  
Kevin J. Kelly ◽  
Pedro A. N. Machado ◽  
Alberto Marchionni ◽  
Yuber F. Perez-Gonzalez

Abstract We propose the operation of LEvEL, the Low-Energy Neutrino Experiment at the LHC, a neutrino detector near the Large Hadron Collider Beam Dump. Such a detector is capable of exploring an intense, low-energy neutrino flux and can measure neutrino cross sections that have previously never been observed. These cross sections can inform other future neutrino experiments, such as those aiming to observe neutrinos from supernovae, allowing such measurements to accomplish their fundamental physics goals. We perform detailed simulations to determine neutrino production at the LHC beam dump, as well as neutron and muon backgrounds. Measurements at a few to ten percent precision of neutrino-argon charged current and neutrino-nucleus coherent scattering cross sections are attainable with 100 ton-year and 1 ton-year exposures at LEvEL, respectively, concurrent with the operation of the High Luminosity LHC. We also estimate signal and backgrounds for an experiment exploiting the forward direction of the LHC beam dump, which could measure neutrinos above 100 GeV.


Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3262
Author(s):  
Md Sultan Mahmud ◽  
Azlan Zahid ◽  
Long He ◽  
Phillip Martin

Reducing risk from pesticide applications has been gaining serious attention in the last few decades due to the significant damage to human health, environment, and ecosystems. Pesticide applications are an essential part of current agriculture, enhancing cultivated crop productivity and quality and preventing losses of up to 45% of the world food supply. However, inappropriate and excessive use of pesticides is a major rising concern. Precision spraying addresses these concerns by precisely and efficiently applying pesticides to the target area and substantially reducing pesticide usage while maintaining efficacy at preventing crop losses. This review provides a systematic summary of current technologies used for precision spraying in tree fruits and highlights their potential, briefly discusses factors affecting spraying parameters, and concludes with possible solutions to reduce excessive agrochemical uses. We conclude there is a critical need for appropriate sensing techniques that can accurately detect the target. In addition, air jet velocity, travel speed, wind speed and direction, droplet size, and canopy characteristics need to be considered for successful droplet deposition by the spraying system. Assessment of terrain is important when field elevation has significant variability. Control of airflow during spraying is another important parameter that needs to be considered. Incorporation of these variables in precision spraying systems will optimize spray decisions and help reduce excessive agrochemical applications.


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