scholarly journals STUDY OF THE BOOSTER INJECTION AT KEK

1993 ◽  
Author(s):  
Y. Shoji
Keyword(s):  
Booster Injection

Secondary Response to Booster Injection of Alum-Precipitated Tetanus Toxoid

1971 ◽  
Vol 15 (3) ◽  
pp. 273-275 ◽  
Author(s):  
Naohide Takayama ◽  
Nobuo Sakurai ◽  
Muneharu Nakayama
Keyword(s):  
Tetanus Toxoid ◽  
Secondary Response ◽  
Booster Injection

scholarly journals THE X-Y-Z SCHEME OF IMMUNOCYTE MATURATION

1968 ◽  
Vol 127 (2) ◽  
pp. 307-325 ◽  
Author(s):  
Vera S. Byers ◽  
Eli E. Sercarz
Keyword(s):  
Lymph Node ◽  
Antibody Response ◽  
Lymph Nodes ◽  
Large Dose ◽  
Primary Response ◽  
Memory Cells ◽  
Secondary Antibody ◽  
Booster Injection

A set of conditions has been described under which primed rabbit lymph nodes produce a secondary antibody response upon in vivo stimulation with a large dose of antigen, but are subsequently "exhausted;" that is, lymph node cultures prepared at intervals following the booster injection cannot be re-stimulated to display tertiary responses. Rabbits given 100-fold less antigen in the booster inoculum were able to give a tertiary response upon in vitro challenge. The system used permits neither induction nor continuation of a primary response to BSA in vitro. Since it could be demonstrated that no memory cells were generated by the booster injection within the intervals between in vivo injection and culture, the tertiary response in nonexhausted nodes must have been due to residual memory cells which remained untriggered by the in vivo booster injection. The unresponsive state was not caused by antibody feedback. These results are interpreted to mean that a population of memory cells can be exhausted by a supraoptimal dose of antigen, rendering the node temporarily incapable of further response. This implies that long-lived memory is not due to asymmetric division of memory cells. The source and fate of memory cells is discussed with regard to this evidence.

Revision of the Thai Red Cross intradermal rabies post-exposure regimen by eliminating the 90-day booster injection

Vaccine ◽  
2006 ◽  
Vol 24 (16) ◽  
pp. 3084-3086 ◽  
Author(s):  
P KHAWPLOD ◽  
H WILDE ◽  
S SIRIKWIN ◽  
M BENJAWONGKULCHAI ◽  
S LIMUSANNO ◽  
...  
Keyword(s):  
Red Cross ◽  
Booster Injection ◽  
Post Exposure

scholarly journals Immunological characterization of the major chick cartilage proteoglycan and its intracellular localization in cultured chondroblasts: a comparison with Type II procollagen.

1983 ◽  
Vol 97 (6) ◽  
pp. 1724-1736 ◽  
Author(s):  
M Pacifici ◽  
R Soltesz ◽  
G Thal ◽  
D J Shanley ◽  
D Boettiger ◽  
...  
Keyword(s):  
Golgi Complex ◽  
Skin Fibroblasts ◽  
Immunofluorescent Staining ◽  
Cell Protein ◽  
Cytoplasmic Vacuole ◽  
Type Ii ◽  
Chondroitinase Abc ◽  
Characteristic Type ◽  
Booster Injection ◽  
Cartilage Proteoglycan

Polyclonal antibodies were raised in a rabbit against the major proteoglycan of chick sternal cartilage. A total of six antisera was obtained, three after the first booster injection (A1, A2, and A3) and three after the second booster injection (A4, A5, and A6). The A1 antiserum, which was characterized in most detail, immunoprecipitated native as well as chondroitinase ABC-digested or chondroitinase ABC/keratanase-digested cartilage proteoglycan synthesized by cultured chick chondroblasts, but failed to immunoprecipitate the major proteoglycan synthesized by chick skin fibroblasts. This antiserum was also able to immunoprecipitate the cartilage proteoglycan core protein newly synthesized by cultured chondroblasts, but no other major cell protein. However, the late bleed antisera obtained from the same rabbit after a second booster injection reacted with a new chondroblast-specific polypeptide(s) of approximately 60,000 mol wt in addition to the cartilage proteoglycan. By immunofluorescence procedures, the A1 antiserum stained the extracellular proteoglycan matrix of cultured chondroblasts but not that of skin fibroblasts. Following enzymatic removal of the extracellular matrix and cell membrane permeabilization, this antiserum stained primarily a large, juxtanuclear structure. Additional radioautographic evidence suggests that this structure represents the Golgi complex. Similar immunofluorescent staining with antibodies to the cartilage-characteristic Type II collagen revealed that type II procollagen was localized in numerous cytoplasmic, vacuole-like structures which were scattered throughout most of the chondroblast cytoplasm but were notably scanty in the Golgi complex area. In conclusion, our data suggest the transit of the major cartilage proteoglycan through the Golgi complex of cultured chondroblasts and possible differences in the intracellular distribution of newly synthesized cartilage proteoglycan and Type II procollagen.

Zero Gradient Synchrotron Booster Injection

1975 ◽  
Vol 22 (3) ◽  
pp. 1488-1491 ◽  
Author(s):  
D. E. Suddeth ◽  
R. L. Kustom ◽  
D. Schmitt
Keyword(s):  
Booster Injection

scholarly journals Effects of re-immunization of heifers against inhibin on hormonal profiles and ovulation rate

Reproduction ◽  
2004 ◽  
Vol 128 (4) ◽  
pp. 475-482 ◽  
Author(s):  
M S Medan ◽  
S Akagi ◽  
H Kaneko ◽  
G Watanabe ◽  
C G Tsonis ◽  
...  
Keyword(s):  
Follicular Development ◽  
Peak Level ◽  
Ovarian Response ◽  
Ovulation Rate ◽  
Α Subunit ◽  
Oil Emulsion ◽  
Booster Injection ◽  
Hormonal Profiles ◽  
The Mean

To study the effect of re-immunization against inhibin on ovarian response and hormonal profiles, Japanese beef heifers (n = 5) were re-immunized three times with inhibin vaccine (recombinant ovine inhibin α-subunit in oil emulsion, 125 μg ml−1) one year after the primary immunization. Control heifers (n = 5) were injected with placebo (Montanide: Marcol adjuvant alone). Oestrous cycles were synchronized by using prostaglandin F2α (PGF2α) and ovarian response was monitored daily by ultrasonography. Blood samples were collected by jugular venipuncture for assessment of hormonal levels and inhibin antibody titres. In contrast to controls, inhibin re-immunized heifers generated antibodies against inhibin rapidly reaching a peak level 9 days after the first booster injection. The mean concentrations of FSH in re-immunized cows increased significantly in comparison with controls. In addition, there was a significant increase in oestradiol-17β and progesterone levels in re-immunized cows compared with controls. Inhibin re-immunized heifers had a significant increase in small (≥4 < 7 mm), medium (≥7 < 10 mm) and large (≥10 mm in diameter) sized follicles. Moreover, the mean ovulation rate was 5.0 ± 1.1 after the third booster injection in re-immunized heifers compared with control heifers (single ovulation). These results clearly demonstrate that re-immunization of inhibin can be used to enhance ovarian follicular development and ovulation rate. Furthermore, the great number of follicles is a potential source of oocytes that could be harvested for in vitro fertilization and embryo transfer programmes.

scholarly journals Hazard Analysis for 90 MeV Booster Injection Energy Limit

2016 ◽  
Author(s):  
Raymond Fliller ◽  
Stephen Kramer ◽  
Richard Faussete
Keyword(s):  
Hazard Analysis ◽  
Energy Limit ◽  
Booster Injection ◽  
Injection Energy
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