scholarly journals Effect of High-Intensity Intermittent Swimming Training on Fatty Acid Oxidation Enzyme Activity in Rat Skeletal Muscle

2004 ◽  
Vol 54 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Shin Terada ◽  
Izumi Tabata ◽  
Mitsuru Higuchi
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
High Intensity ◽  
Acid Oxidation ◽  
Swimming Training ◽  
Rat Skeletal Muscle ◽  
Fatty Acid Oxidation Enzyme ◽  
Oxidation Enzyme

scholarly journals Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency

2015 ◽  
Vol 24 (11) ◽  
pp. 3238-3247 ◽  
Author(s):  
Manuel Schiff ◽  
Birgit Haberberger ◽  
Chuanwu Xia ◽  
Al-Walid Mohsen ◽  
Eric S. Goetzman ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Fatty Acid ◽  
Disease Severity ◽  
Fatty Acid Oxidation ◽  
Complex I ◽  
Acid Oxidation ◽  
Fatty Acid Oxidation Enzyme ◽  
Complex I Assembly ◽  
Oxidation Enzyme

Fatty Acid Oxidation Enzyme Gene Expression Is Downregulated in the Failing Heart

Circulation ◽  
1996 ◽  
Vol 94 (11) ◽  
pp. 2837-2842 ◽  
Author(s):  
Michael N. Sack ◽  
Toni A. Rader ◽  
Sonhee Park ◽  
Jean Bastin ◽  
Sylvia A. McCune ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
Acid Oxidation ◽  
Enzyme Gene ◽  
Failing Heart ◽  
Fatty Acid Oxidation Enzyme ◽  
Oxidation Enzyme

High-intensity interval training increases intrinsic rates of mitochondrial fatty acid oxidation in rat red and white skeletal muscle

2013 ◽  
Vol 38 (3) ◽  
pp. 326-333 ◽  
Author(s):  
Daisuke Hoshino ◽  
Yuko Yoshida ◽  
Yu Kitaoka ◽  
Hideo Hatta ◽  
Arend Bonen
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
High Intensity ◽  
Interval Training ◽  
Acid Oxidation ◽  
Mitochondrial Fatty Acid Oxidation ◽  
Mitochondrial Fatty Acid ◽  
Mitochondrial Volume ◽  
High Intensity Interval

High-intensity interval training (HIIT) can increase mitochondrial volume in skeletal muscle. However, it is unclear whether HIIT alters the intrinsic capacity of mitochondrial fatty acid oxidation, or whether such changes are associated with changes in mitochondrial FAT/CD36, a regulator of fatty acid oxidation, or with reciprocal changes in the nuclear receptor coactivator (peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1α)) and the corepressor (receptor-interacting protein 140 (RIP140)). We examined whether HIIT alters fatty acid oxidation rates in the isolated subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondria of red and white skeletal muscle and (or) induces changes in muscle PGC-1α and RIP140 proteins and mitochondrial FAT/CD36 protein content. Rats were divided into untrained or HIIT-trained groups. HIIT animals performed 10 bouts of 1-min high-intensity treadmill running (30–55 m·min–1), separated by 2 min of rest, for 5 days a week for 4 weeks. As expected, after the training period, HIIT increased mitochondrial enzymes (citrate synthase, COXIV, and β-hydroxyacyl CoA dehydrogenase) in red and white muscle, indicating that muscle mitochondrial volume had increased. HIIT also increased the rates of palmitate oxidation in mitochondria of red (37% for SS and 19% for IMF) and white (36% for SS and 12% for IMF) muscle. No changes occurred in SS and IMF mitochondrial FAT/CD36 proteins, despite increasing FAT/CD36 at the whole-muscle level (27% for red and 22% for white). Concurrently, muscle PGC-1α protein was increased in red (22%) and white (16%) muscle, but RIP140 was not altered. These results indicate that increases in SS and IMF mitochondrial fatty acid oxidation induced by HIIT are accompanied by an increase in PGC-1α, but not RIP140 or FAT/CD36.

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