scholarly journals High-intensity interval training increases the rate of mitochondrial fatty acid oxidation in rat skeletal muscle

2012 ◽  
Vol 61 (1) ◽  
pp. 55-55
Author(s):  
Daisuke Hoshino ◽  
Yuko Yoshida ◽  
Hideo Hatta
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
High Intensity ◽  
Interval Training ◽  
Acid Oxidation ◽  
High Intensity Interval Training ◽  
Rat Skeletal Muscle ◽  
Mitochondrial Fatty Acid Oxidation ◽  
Mitochondrial Fatty Acid ◽  
High Intensity Interval

High-intensity interval training increases intrinsic rates of mitochondrial fatty acid oxidation in rat red and white skeletal muscle

2013 ◽  
Vol 38 (3) ◽  
pp. 326-333 ◽  
Author(s):  
Daisuke Hoshino ◽  
Yuko Yoshida ◽  
Yu Kitaoka ◽  
Hideo Hatta ◽  
Arend Bonen
Keyword(s):  
Skeletal Muscle ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
High Intensity ◽  
Interval Training ◽  
Acid Oxidation ◽  
Mitochondrial Fatty Acid Oxidation ◽  
Mitochondrial Fatty Acid ◽  
Mitochondrial Volume ◽  
High Intensity Interval

High-intensity interval training (HIIT) can increase mitochondrial volume in skeletal muscle. However, it is unclear whether HIIT alters the intrinsic capacity of mitochondrial fatty acid oxidation, or whether such changes are associated with changes in mitochondrial FAT/CD36, a regulator of fatty acid oxidation, or with reciprocal changes in the nuclear receptor coactivator (peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1α)) and the corepressor (receptor-interacting protein 140 (RIP140)). We examined whether HIIT alters fatty acid oxidation rates in the isolated subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondria of red and white skeletal muscle and (or) induces changes in muscle PGC-1α and RIP140 proteins and mitochondrial FAT/CD36 protein content. Rats were divided into untrained or HIIT-trained groups. HIIT animals performed 10 bouts of 1-min high-intensity treadmill running (30–55 m·min–1), separated by 2 min of rest, for 5 days a week for 4 weeks. As expected, after the training period, HIIT increased mitochondrial enzymes (citrate synthase, COXIV, and β-hydroxyacyl CoA dehydrogenase) in red and white muscle, indicating that muscle mitochondrial volume had increased. HIIT also increased the rates of palmitate oxidation in mitochondria of red (37% for SS and 19% for IMF) and white (36% for SS and 12% for IMF) muscle. No changes occurred in SS and IMF mitochondrial FAT/CD36 proteins, despite increasing FAT/CD36 at the whole-muscle level (27% for red and 22% for white). Concurrently, muscle PGC-1α protein was increased in red (22%) and white (16%) muscle, but RIP140 was not altered. These results indicate that increases in SS and IMF mitochondrial fatty acid oxidation induced by HIIT are accompanied by an increase in PGC-1α, but not RIP140 or FAT/CD36.

scholarly journals High-Intensity Interval Training Improves Markers of Oxidative Metabolism in Skeletal Muscle of Individuals With Obesity and Insulin Resistance

2018 ◽  
Vol 9 ◽  
Author(s):  
Mariana Aguiar de Matos ◽  
Dênia Vargas Vieira ◽  
Kaio Cesar Pinhal ◽  
Jennifer Freitas Lopes ◽  
Marco Fabrício Dias-Peixoto ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Oxidative Metabolism ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

Effects of one‐legged high‐intensity interval training on insulin‐mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

2019 ◽  
Vol 226 (2) ◽  
pp. e13245 ◽  
Author(s):  
Flemming Dela ◽  
Arthur Ingersen ◽  
Nynne B. Andersen ◽  
Maria B. Nielsen ◽  
Helga H. H. Petersen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Glucose Homeostasis ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval
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