scholarly journals Chloroquine treatment against naturally occuring Giardia duodenalis infection in dogs

2017 ◽  
Vol 73 (5) ◽  
pp. 280-283
Author(s):  
Kerem Ural ◽  
Mehmet Gultekin ◽  
Serdar Pasa ◽  
Nuran Aysul ◽  
Adnan Ayan
Keyword(s):  
Treatment Group ◽  
Giardia Duodenalis ◽  
Rapid Test ◽  
Control Group ◽  
Effective Treatment Option ◽  
Geometric Means ◽  
Group I ◽  
Chloroquine Treatment ◽  
Before And After ◽  
And Control

The aim of the present study was to evaluate the efficacy of chloroquine on lessening or eliminating cyst shedding in dogs naturally infected with Giardia duodenalis. A total of 26 dogs naturally infected with G. duodenalis, from various breeds, ages and of both sexes were selected and randomly assigned into two groups based on treatment (group I, n=20 dogs treated orally with 2.5 mg/kg chloroquine twice daily for 5 consecutive days) and control (group II, n=6 untreated control dogs). Diagnosis was based on microscopic faecal examination and rapid test kits. Cyst excretion was determined on days 0, 3, 7 and 10, before and after treatment. Evaluation of the percentage reduction in cyst excretion revealed 99.8% efficacy on day 3 and 99.9 % on days 7 and 10 in the treatment group. Geometric means of the number of excreted cysts did not change significantly in the control group. Chloroquine at the proposed dosage might be a practical in application, low priced and highly effective treatment option in dogs with giardiasis.

The efficacy of chloroquine treatment of Giardia duodenalis infection in calves

2016 ◽  
Vol 85 (6) ◽  
pp. 335-341
Author(s):  
M. Gultekin ◽  
K. Ural ◽  
N. Aysul ◽  
A. Ayan ◽  
C. Balikci ◽  
...  
Keyword(s):  
Placebo Group ◽  
Treatment Group ◽  
Gene Sequence ◽  
Giardia Duodenalis ◽  
Control Group ◽  
Geometric Means ◽  
Group I ◽  
Chloroquine Treatment ◽  
Gene Sequence Analysis ◽  
Before And After

The purpose of the present study was to evaluate the effect of chloroquine treatment on cyst excretion in calves naturally infected with Giardia duodenalis. The calves were randomly assigned into two groups based on placebo (group I, n=7 untreated control calves) or treatment (group II, n=7 calves treated orally with 2.5 mg/kg chloroquine twice daily for five consecutive days). The G. duodenalis isolates were identified by molecular characterization with β-giardin nested PCR and gene sequence analysis as assemblage A3. Cyst excretion was determined on days 0, 3, 7 and 10, before and after treatment. Geometric means of the number of excreted cysts did not change significantly in the control group during the trial. The reduction in cyst excretion after chloroquine treatment was 99% on day 3 and 100% on days 7 and 10. Chloroquine treatment is most probatly practically applicable, relatively inexpensive and highly effective against giardiosis in calves.

scholarly journals Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs

2014 ◽  
pp. 4023-4032 ◽  
Author(s):  
Kerem Ural ◽  
Nuran Aysul ◽  
Huseyin Voyvoda ◽  
Bulent Ulutas ◽  
Osman S. Aldemir ◽  
...  
Keyword(s):  
Single Dose ◽  
Treatment Group ◽  
Clinical Signs ◽  
Giardia Duodenalis ◽  
Positive Control ◽  
Control Group ◽  
Giardia Cyst ◽  
Effective Treatment Option ◽  
Faecal Consistency ◽  
Before And After

ABSTRACTObjective. The purposes of this study were to determine whether secnidazole administered at a single dose of 10 mg/kg, orally, lessens or eliminates Giardia cyst shedding, and to validate the benefit of secnidazole treatment on clinical signs and faecal consistency in lambs naturally infected with Giardia duodenalis. Materials and methods. To this extent weaned 12 weeks of age lambs were selected and randomly assigned into two groups based on placebo (group C, n=7 untreated control group) or treatment (group S, n=10 lambs treated with a single dose of secnidazole at 10 mg/kg). Results. On days 0 and 10, before and after treatment, respectively, reduction in cyst excretion was determined. The faecal consistency and general health were recorded at each sampling day. Conclusions. During the study there was a high (99.98%) reduction in cyst excretion in the secnidazol treatment group compared to the positive control group on day 10, resulting in a significant (p<0.001) reduction, making secnidazole highly effective treatment option.

scholarly journals The efficacy of chloroquine treatment against naturally occuring Giardia duodenalis infection in lambs

2016 ◽  
pp. 5328-5335
Author(s):  
Umit Karademir ◽  
Kerem Ural ◽  
Nuran Aysul ◽  
Adnan Ayan ◽  
Songul Toplu ◽  
...  
Keyword(s):  
Placebo Group ◽  
Treatment Group ◽  
Untreated Control ◽  
Giardia Duodenalis ◽  
Control Group ◽  
Untreated Control Group ◽  
Effective Treatment Option ◽  
Chloroquine Treatment ◽  
Los Grupos ◽  
Very High

Objective. The aim of the present study was to determine the efficacy of Chloroquine (Cq), an antimalarial medicine, administered at a dose of 2.5 mg/kg, orally, during 5 consecutive days, in Sakiz and Merino lambs naturally infected with Giardia duodenalis. Materials and methods. To this extent weaned 10 weeks of aged lambs were enrolled and randomly assigned into two groups based on treatment (group C, n=18 lambs treated with Cq) and placebo (group P, n=8 untreated control animals). Diagnosis was based on detection of trophozoit and/or cysts on fecal flotation. Cyst count per gram feces (days 0, 3, 7 and 10) was analyzed among groups. Results. During the trial, regarding the efficacy of Cq on days 3., 7., and 10. There was significant (p<0.01) reduction in cyst excretion; whereas evaluation of mean geometric cyst excretion revealed 100% reduction. Conclusions. There was a very high (100%) reduction in cyst excretion in the Cq treatment group compared to the positive untreated control group on days 3, 7 and 10, resulting in a significant (p<0.001) reduction, making Cq, safety, and thus highly effective treatment option of lambs with naturally occuring giardiasis.Objetivo. El objetivo del presente estudio fue determinar la eficacia de la cloroquina, un medicamento contra la malaria, administrado a una dosis de 2.5 mg/kg, por vía oral, durante 5 días consecutivos, en Corderos Sakiz y Merino infectados naturalmente con Giardia duodenalis. Materiales y metodos. En esta medida destetados 10 semanas de edad fueron incluidos y asignados al azar en dos grupos sobre la base del tratamiento (grupo C, n = 18 corderos tratados con cloroquina) y placebo (grupo P, n = 8 animales de control no tratados). El diagnóstico se basa en la detección de trophozoit y/o quistes en la flotación fecal. Quiste recuento por gramo de heces (día 0, 3, 7 y 10) se analizó entre los grupos. Resultados. Respecto a la eficacia de la cloroquina en los días 3, 7 y 10 existió una reducción significativa (p<0.01) en la excreción de quistes; mientras que la evaluación de la media de la excreción Rev.MVZ Córdoba 21(2):5328-5335, 2016. ISSN: 0122-0268 ORIGINAL 5329 de quistes reveló una reducción del 100%. Conclusiones. Durante el estudio hubo una reducción del 100% en la excreción de quistes en el grupo de tratamiento con cloroquina en comparación con el grupo control no tratado positivo en los días 3, 7 y 10, lo que resulta en una disminución significativa (p<0.001) por lo que la cloroquina razonablemente es una opción de tratamiento por el costo, seguridad, y por lo tanto muy eficaz de corderos infectados naturalmente con giardiasis.

scholarly journals PERBEDAAN PENURUNAN TEKANAN DARAH PRA LANSIA PRE HIPERTENSI YANG DIBERI JUS TOMAT (Lycopersicum grandifilum)

2018 ◽  
Vol 10 (2) ◽  
pp. 152-158
Author(s):  
Hari Yani Fadillah
Keyword(s):  
Blood Pressure ◽  
Treatment Group ◽  
Block Design ◽  
Pressure Control ◽  
Tomato Juice ◽  
Control Group ◽  
Randomized Block Design ◽  
Before And After ◽  
Blood Pressure Treatment ◽  
And Control

The research aims to know the effect of tomato juice on blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.The design of research was a quasi experiment include pre test post test. This population was all patients posbindu aged 45-59 years. Sampling of this research randomized block design of one factorial were 6 samples divided into treatment and control group. The data which have been analyzed using univariate and bivariate. From this research were obtained the results such as the mean of sistole blood pressure before and after intervention in treatment group p = 0,273 and diastole p = 0,27. Mean systole blood pressure control group p = 0.060 and diastole p = 2.14. Distribution of tomato juice (Lycopersicum grandifilum) did not given affect the decrease in blood pressure of systole diastole before and after intervention in pre-elderly pre hypertension. Whereas the difference in mean systole of blood pressure treatment and control group p = 0.935 and diastolic of blood pressure p = 0.678. There ware not difference in mean of blood pressure in the tomato juice treatment group and control of Vitamin C. The result concluded there were not effect of tomato juice (Lycopersicum grandifilum) on systolic of blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.

scholarly journals The Effect of Occupatioal Therapy on Social Skill in Schizofrenia with Social Isolation

2014 ◽  
Vol 1 (2) ◽  
pp. 081-086
Author(s):  
Rendra Sukmana ◽  
Nawang Wulandari
Keyword(s):  
Social Skills ◽  
Treatment Group ◽  
Occupational Therapy ◽  
Social Isolation ◽  
Rank Test ◽  
Control Group ◽  
Before And After ◽  
Physical Disorders ◽  
Social Capability ◽  
And Control

Occupational therapy is a healing effort against someone who is experiencing mental and physical disorders by giving liveliness job. The purpose of the study to determine the effect of Occupational Therapy on social skills in schizophrenia with social isolation, using Quasy Control Group Pre-test Posttest Design. Sampel used in this experiments were 10 respondents that are divided into 2 groups: treatment and control. The treatment group was given occupational therapy 2 times a week for 3 weeks. Observations by 12 questions was conducted to determine the level of social skills of respondents. The results of this study showed no increase on the level of social skills before and after given granted Occupational Therapy. The level of social capability of 5 respondents in the treatment group before given an Occupational Therapy were 7 and while after given an occupational therapy were 10.2. This result have contrast to the control group which showed level of social capability were 7 . Statistic Analized using Wilcoxon Sign Rank Test showed significant is 0.0205 in the group between pre and post treatment, while the treatment and control group comparisons with Mann Whitney U test showed 0.029 ≤ 0.05. With these results Occupational Therapy can improve social skills clients with social isolation.

scholarly journals Pengaruh suplementasi Zn terhadap perubahan indeks TB/U anak stunted usia 24-36 bulan

2017 ◽  
Vol 5 (2) ◽  
pp. 98-104
Author(s):  
Dewi Pertiwi Dyah Kusudaryati ◽  
Siti Fatimah Muis ◽  
Laksmi Widajanti
Keyword(s):  
Treatment Group ◽  
Dietary Intake ◽  
Child Growth ◽  
Control Group ◽  
Control Group Design ◽  
Dietary Allowance ◽  
Significant Difference ◽  
Before And After ◽  
And Control ◽  
Height For Age

Background : Zn supplementation on stunted children in multiple research get the result inconsistent concerning the effect of Zn on children’s growth.Objective : To examine the effect of Zn supplementation to the change in height for index among stunted children age between 24-36 months.Methods: The research design is randomized pretest posttest control group design. The total of thirty six stunted children are divided into two groups. The treatment group is received syrup with 20 mg ZnSO4 twice a week for three months. The control group received placebo without Zn. Height for age z score (HAZ) on WHO Child Growth 2006 is used to measure height for age index while dietary intake and infection diseases are used as confounding variables.Result : There is significant difference in HAZ before and after supplementation at treatment group (p<0.001) and control group (p<0.001). There is a significant difference of the change in HAZ between the treatment group and control group (p=0.006). Percentage Achievement of Energy, Protein, and Zn Dietary Allowance have significant difference between the treatment group and control group (p=0.009; p<0.001; p<0.001, respectively). The change in HAZ, Percentage Achievement of Energy, Protein, and Zn Dietary Allowance are higher in treatment group than control group. Duration of diarrhea (p=0.045) and morbidity (p=0.019) are lower in treatment group than control group. Conclusion : Zn Supplementation among stunted children have significant effect on the change in HAZ, dietary intake, and infection.

Split weaning increases the growth of light piglets during lactation

1996 ◽  
Vol 47 (4) ◽  
pp. 513 ◽  
Author(s):  
JR Pluske ◽  
IH Williams
Keyword(s):  
Treatment Group ◽  
Milk Intake ◽  
Control Group ◽  
Milk Consumption ◽  
Video Recorder ◽  
Before And After ◽  
And Control

The mechanisms of increased growth of small piglets following split weaning were studied using a total of 10 sows and 100 piglets. Sows and their litters were allocated to a treatment group (piglets split-weaned) or control group (no piglets split-weaned). At day 22 of lactation, piglets in each litter were classified as either 'heavy' or 'light', with equal numbers in each group. 'Heavy' piglets were removed from sows at day 22 (s.e.m. 0.17) in split-weaned litters while 'light' piglets remained with their mothers for an extra week. At 29.5 (s.e.m. 0.21) days of age, sows from both split-weaned and control litters were weaned. Milk consumption was estimated between days 16 and 19 and on day 24 of lactation by weighing piglets before and after sucking. During milk letdown, the teats that piglets sucked from were noted. A video recorder was used to determine the frequency of natural sucklings, the proportion of unsuccessful sucklings, and the time taken for piglets to consume milk during ejection, over a 16-h period before and after split weaning. 'Light' piglets in split-weaned litters grew 61% faster (P < 0.001) than their counterparts in control litters and were 15% heavier (P < 0.01) at weaning. This was explained by a 49% increase in milk intake (64 v. 43 g/sucking, P 5 0.001). Increased milk intake was due to multiple teat swapping with an associated longer duration of sucking during letdown. 'Heavy' piglets weaned at 22 days were lighter at 29 days than their counterparts in control litters (P < 0.01). Gains in growth made by 'light' piglets in split-weaned sows over their counterparts in control litters had disappeared by the time pigs were 9 weeks old, and piglets classed as 'heavy' at day 22 of lactation remained heavier ( P < 0.001) at 62 days of age irrespective of treatment.

scholarly journals PENGARUH PEMBERIAN JUS LIDAH BUAYA TERHADAP KADAR GLUKOSA DARAH PUASA PADA WANITA PREDIABETES

2012 ◽  
Vol 1 (1) ◽  
pp. 107-114 ◽  
Author(s):  
Putri Sukma Pertiwi ◽  
Hesti Murwani Rahayuningsih
Keyword(s):  
Treatment Group ◽  
Fasting Blood Glucose ◽  
Aloe Vera ◽  
Wilcoxon Test ◽  
Control Group ◽  
Food Record ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
And Control

Background: Prediabetes is a condition which pioneers of DM. Diet management is the effective method to decrease fasting blood glucose (FBG) level. One of plant that correlates decreasing FBG level is Aloe vera. The purpose of  the study was to prove the effects of Aloe vera on FBG level in prediabetes women. Method: This study was quasi experiment with pre test-post test design. The subjects were people in Tlogosari Kulon Semarang who taken by consecutive sampling. Total subjects were 26 people which was divided in 2 groups. The treatment group was given juice Aloe vera 150 gram per day during 14 days and control group was not given juice Aloe vera. FBG level was measured before and after intervention using spectrofotometri method. During intervention, both of group recorded food intake using food record and food recall. Data was analyzed by Independent sample t-test, Mann Whitney test, and Wilcoxon test. Result : The decreasing of FBG level in treatment group was 20.38±14.7 (18.92%) mg/dl and control group was 0.38±11.12 mg /dl. Statistic analysis showed that there was significant difference at decreasing of FBG level in treatment group and control group. Conclusion : There was significant decreasing FBG level 20.38 mg/dl after given juice Aloe vera 150 gram per day during 14 days.

scholarly journals Pengaruh Teknik Relaksasi Afirmasi terhadap Stres Mahasiswa yang Menempuh Skripsi di Program Studi Ilmu Keperawatan Universitas Jember

2018 ◽  
Vol 6 (2) ◽  
pp. 319
Author(s):  
Rommiyatun Zainiyah ◽  
Erti Ikhtiarini Dewi ◽  
Wantiyah Wantiyah
Keyword(s):  
Treatment Group ◽  
Sampling Technique ◽  
T Test ◽  
Control Group ◽  
Final Project ◽  
Parasympathetic Nerves ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
And Control

One of stressor in college students is taking a final project as a graduation requirement. The body'sresponse toward stress includes a rise of heart rate, diarrhea and insomnia. One of stressmanagement is affirmation relaxation (AR) technique. This research aimed to analyze the influenceof AR technique towards stress on students who take a final project in Faculty of Nursing, UniversityOf Jember. This research used a quasi experiment with Pretest-Post test approach and controlgroup design. Sampling technique that used is purposive sampling with respondent divided into twogroups, the treatment group and control group with 15 respondents for each group. Data wasanalyzed by using Dependent t test and Independent t test with 95% CI. The result showed thatthere was a significant difference stress before and after given AR technique within average 19,2 to10,87 (p = 0,001). Mean while, there was no significant difference of stress between pretest and posttest in control group within average 18,73 to 18,4 (p = 0,841). Overall, there was a difference ofstress between treatment group and control group (p =0,02, α = 0,05). The AR techniques reducestress because it can influence the sympathetic and parasympathetic nerves to produce endorphinehormone. The conclusion of this research is there was an influence of AR technique towards stresson students who Taking a Final Project in Faculty of Nursing University of Jember.Keywords: affirmation relaxation technique, stress, final project.

scholarly journals Treatment of Non-erosive Effect of Clinical Study of Gastroesophageal Reflux Disease

2018 ◽  
Vol 6 (3) ◽  
Author(s):  
Qian Liu
Keyword(s):  
Treatment Group ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Control Group ◽  
Significant Difference ◽  
Before And After ◽  
And Control

<p class="18">Abstract: Objective: To observe the clinical effect of “Chaihu Shugan Powder Zuojin Pill” in the treatment of non-erosive gastroesophageal reflux disease. Methods: Sixty patients with non-erosive gastroesophageal reflux disease were randomly divided into treatment group and control group (30 cases in each group). The patients were treated with “Zaohu Shugan Powder” and “Zangjin Pills” and omeprazole respectively. For 8 weeks, the clinical efficacy and changes in clinical symptoms were observed. Results: The total effective rate was 93.3% in the treatment group and 80.0% in the control group. There was significant difference between the two groups before and after treatment (P &lt;0.05). Conclusion: “Chaihu Shugan Powder Zuojin Pill” can effectively improve the clinical symptoms of non-erosive gastroesophageal reflux disease.</p>

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