scholarly journals Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production

2016 ◽  
Vol 63 (3.4) ◽  
pp. 187-191 ◽  
Author(s):  
Shinya Yoshida ◽  
Koji Yasutomo ◽  
Toshiyuki Watanabe
Keyword(s):  
Atopic Dermatitis ◽  
Skin Disease ◽  
Ltb4 Production

scholarly journals Substantiation of Using Pimecrolimus 1% Cream in Proactive Therapy of Children with Atopic Dermatitis

2021 ◽  
Vol 20 (5) ◽  
pp. 376-382
Author(s):  
Nikolay N. Murashkin ◽  
Roman A. Ivanov ◽  
Eduard T. Ambarchian ◽  
Roman V. Epishev ◽  
Alexander I. Materikin ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Maintenance Therapy ◽  
Skin Disease ◽  
Pediatric Population ◽  
Efficacy And Safety ◽  
Inflammatory Skin Disease ◽  
High Prevalence ◽  
Proactive Therapy ◽  
Term Maintenance

Atopic dermatitis (AtD) is multifactorial inflammatory skin disease with high prevalence in pediatric population. It is crucial to implement long-term maintenance therapy to prevent AtD exacerbations according to current clinical guidelines and expert reports. The article summarizes the results of the major studies on using pimecrolimus 1% cream. Its efficacy and safety in long-term proactive therapy of children with AtD are presented.

scholarly journals Crocin ameliorated skin tissue inflammation in atopic dermatitis in mice

2020 ◽  
Vol 6 (2) ◽  
pp. 142
Author(s):  
Abdullah Alyoussef
Keyword(s):  
Atopic Dermatitis ◽  
Protein Expression ◽  
Skin Disease ◽  
Therapeutic Effects ◽  
Inflammatory Skin Disease ◽  
Mice Model ◽  
Subsequent Reduction ◽  
Gardenia Jasminoides ◽  
Tnf Α ◽  
Gene And Protein Expression

<p class="abstract"><strong>Background:</strong> Atopic dermatitis (AD) is considered a chronic recurrent inflammatory skin disease. In addition, crocin is the major carotenoid compound found in Gardenia jasminoides. It is previously proved to produce anti-inflammatory actions. Therefore, we conducted this research to investigate the therapeutic effects of crocin on a mice model of AD.</p><p class="abstract"><strong>Methods:</strong> Mice were investigated for the number of scratches and dermatitis score. Skin was isolated and used for measurements of gene and protein expression of β-catenin, NFκB, TNF-α and IL-1β.<strong></strong></p><p class="abstract"><strong>Results:</strong> Authors found that crocin significantly reduced the number of scratches, ear thickness and dermatitis score. In addition, crocin ameliorated AD-induced elevation in the expression of β-catenin, NFκB, TNF-α and IL-1β.</p><p class="abstract"><strong>Conclusions:</strong> Crocin ameliorated DNCB-induced AD in mice via blockage of β-catenin with subsequent reduction in inflammatory pathway.</p><p class="abstract"> </p>

scholarly journals PSYCHOSOCIAL IMPACT OF COMMON SKIN DISORDERS – A REVIEW STUDY

2021 ◽  
Vol 9 (7) ◽  
pp. 1452-1456
Author(s):  
Manish Choudhari ◽  
Nikita Jamadari ◽  
Naresh Jain
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Skin Disease ◽  
Skin Diseases ◽  
Fungal Infections ◽  
Acne Vulgaris ◽  
Well Being ◽  
Psychosocial Impact ◽  
Common Skin

Objective - To increase awareness of the psychosocial impact of Kushtha, Visarpa, Mukhadushika, Sheetpitta, Udarda and Kotha in Ayurveda and Acne vulgaris, Urticaria, Various types of fungal infections, Atopic dermatitis, Psoriasis etc. in modern point of view. Quality Of Evidence - A literature review was based on a MEDLINE search (1966 to 2000). Selected articles from the dermatologic and psychiatric literature, as well as other relevant medical journals, were reviewed and used as the basis for discussion of how skin disease affects patients’ lives and of appropriate management. Message - Dermatologic problems hurt patients’ quality of life. skin disease can produce stress, anxiety, anger, depression, low self-esteem, embarrassment, and other psychological, personal, professional and social life problems that affect patients’ lives in ways comparable to arthritis or other disabling illnesses, as well as showing a bidirectional relationship between skin disease and psychological distress. This review focuses on the effects of five common skin diseases seen by family physicians- Acne, Urticaria, Various types of fungal infections, Atopic dermatitis and Psoriasis. Conclusion - How skin disease affects psychosocial well-being is un- derappreciated. Increased understanding of the psychiatric comorbidity associated with skin disease and a biopsy- chosocial approach to management will ultimately improve patients’ lives. Keywords: Skin disease, Psychosocial Impact, Quality of life.

scholarly journals Wearing a mask and skin disease: patients with atopic dermatitis speak it out

2020 ◽  
Author(s):  
S. Merhand ◽  
L. Misery ◽  
V. Delvigne ◽  
C. Le Floch ◽  
C. Taïeb
Keyword(s):  
Atopic Dermatitis ◽  
Skin Disease

scholarly journals Exacerbation of Atopic Dermatitis after Bacillus Calmette-Guérin Vaccination

1998 ◽  
Vol 91 (3) ◽  
pp. 133-134 ◽  
Author(s):  
S J Dalton ◽  
M R Haeney ◽  
Leena Patel ◽  
T J David
Keyword(s):  
Atopic Dermatitis ◽  
Skin Disease ◽  
Cytokine Profile ◽  
Routine Vaccination ◽  
Severe Exacerbation ◽  
Bacillus Calmette Guerin ◽  
Activated Lymphocytes ◽  
Bcg Vaccination ◽  
Cause And Effect ◽  
Stimulation Of

In two children with atopic dermatitis, routine vaccination with bacillus Calmette-Guérin (BCG) was followed by severe exacerbation of skin disease. If the sequence is cause and effect, a possible mechanism is stimulation of a Th2 lymphocyte cytokine profile by the vaccine, with migration of activated lymphocytes to inflamed skin. In children with active atopic dermatitis, BCG vaccination is best deferred until remission.

scholarly journals Atopic Dermatitis: Global Epidemiology and Risk Factors

2015 ◽  
Vol 66 (Suppl. 1) ◽  
pp. 8-16 ◽  
Author(s):  
Sophie Nutten
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Low Income ◽  
Skin Disease ◽  
Complex Disease ◽  
Symptom Control ◽  
Clinical Manifestations ◽  
Low Income Countries ◽  
Skin Barrier Function ◽  
Global Epidemiology

Atopic dermatitis (AD) is a chronic inflammatory skin disease posing a significant burden on health-care resources and patients' quality of life. It is a complex disease with a wide spectrum of clinical presentations and combinations of symptoms. AD affects up to 20% of children and up to 3% of adults; recent data show that its prevalence is still increasing, especially in low-income countries. First manifestations of AD usually appear early in life and often precede other allergic diseases such as asthma or allergic rhinitis. Individuals affected by AD usually have genetically determined risk factors affecting the skin barrier function or the immune system. However, genetic mutations alone might not be enough to cause clinical manifestations of AD, and it is merely the interaction of a dysfunctional epidermal barrier in genetically predisposed individuals with harmful effects of environmental agents which leads to the development of the disease. AD has been described as an allergic skin disease, but today, the contribution of allergic reactions to the initiation of AD is challenged, and it is proposed that allergy is rather a consequence of AD in subjects with a concomitant underlying atopic constitution. Treatment at best achieves symptom control rather than cure; there is thus a strong need to identify alternatives for disease prevention.

Alternative therapeutic advantages of catfish bile on atopic dermatitis: protection of T cell-mediated skin disease via antioxidant activities

2011 ◽  
Vol 63 (10) ◽  
pp. 1327-1335 ◽  
Author(s):  
Do Ik Lee ◽  
Yoon Joo Huh ◽  
Kwang Woo Hwang ◽  
YoungWook Choi ◽  
Jae-Seok Choi ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
T Cell ◽  
Skin Disease ◽  
Antioxidant Activities
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