scholarly journals BIOLOGICAL IMPACT OF CINNAMON EXTRACT VS. DIAZEPAM ON SUBMANDIBULAR SALIVARY GLANDS OF STRESSED ALBINO RATS.

2016 ◽  
Vol 4 (10) ◽  
pp. 1917-1928
Author(s):  
ElhamHassan Hassan ◽  
◽  
LailaElsayed Amin ◽  
MohamedI. Mourad ◽  
HebaMahmoud Elsabaa ◽  
...  
1959 ◽  
Vol 196 (4) ◽  
pp. 827-830 ◽  
Author(s):  
Herbert Wells ◽  
S. Jerome Zackin ◽  
Paul Gold-Haber ◽  
Paul L. Munson

Periodic amputation of the erupted portion of the lower incisors of albino rats resulted in a marked increase in the wet and dry weight of the submandibular salivary glands as early as 7 days after the first amputation. Enlargement of both serous and mucous acini was observed, but no effect on the cells of the tubules could be detected. Amputation of the upper incisors alone did not result in enlargement of the submandibular glands. Hypophysectomy decreased the extent of the response to amputation of the lower incisors but did not abolish it. Chronic treatment with cortisone had no significant effect on the weight of the glands. A reflex neurologic explanation was offered as a tentative basis for understanding the phenomenon and as a starting point for further investigation.


2021 ◽  
Vol 8 (12) ◽  
pp. 219
Author(s):  
Mahmoud M. Bakr ◽  
Mahmoud M. Al-Ankily ◽  
Sara M. Shogaa ◽  
Mohamed Shamel

Silver nanoparticles (AgNPs) are extensively used in many industries due to their superior antimicrobial properties. However, it is evident from many studies that AgNPs has cytotoxic potential through its effect on excessive formation of reactive oxygen species (ROS). The aim of this study was to examine the toxic effect of AgNPs on the submandibular salivary glands and the attenuating effect of vitamin E, as a natural antioxidant, against this toxicity. Thirty Albino rats were divided into 3 groups (n = 10): control group, AgNPs group receiving 2 mg/kg daily for 28 days, and AgNPs and vitamin E group receiving AgNPs the same as the previous group in addition to vitamin E at a dose of 100 mg/kg. Microscopic, ultrastructural, and cytokeratin immune-reactivity examination of the glands were performed. The AgNPs group showed noticeable degeneration in all structures of the gland as evident in the histological and ultrastructural examination. The AgNPs and vitamin E group revealed an improvement of the glandular elements. A significant increase in cytokeratin immune expression was found after comparison of both groups (p = 0.01). This current study shows that vitamin E has powerful antioxidant properties, which can combat the cytotoxic effect caused by AgNPs. Further studies are deemed necessary to confirm this finding using other immunohistochemical markers, such as myosin and E-cadherin.


2018 ◽  
Vol 64 (2) ◽  
pp. 1293-1303
Author(s):  
Radwa El-sharkawy ◽  
Hala El-kammar ◽  
Raneem Obeid ◽  
Abdelfattah Bdelkhalek

2020 ◽  
Vol 8 (A) ◽  
pp. 49-54
Author(s):  
Sarah Yasser ◽  
Ahmed Shon

AIM: This study was designed to compare the effect of diabetes on the mucous and seromucous acini of the sublingual (SLG) and the submandibular (SMG) salivary glands of albino rats, respectively. METHODS: Twenty male albino rats were assigned into two groups; control and diabetic. Three months following the induction of diabetes mellitus (DM), both the SMG and the SLG glands were removed, randomly sectioned and stained with hematoxylin and eosin to estimate the volume-weighted mean volume of the acini of both glands together with examining their morphology. Furthermore, immunohistochemistry was done to examine the expression of the proliferating cell nuclear antigen (PCNA) in both of them. RESULTS: We found that, unlike the SMG acinar cells, diabetes appeared not to affect both the morphology and the volume of the SLG acini. Interestingly, PCNA expression in diabetic SMG glands acini was significantly higher than diabetic SLG glands acini. Furthermore, we found that the expression pattern of PCNA was significantly higher between the control and diabetic groups in both glands. CONCLUSION: We concluded that the mucous acini of the SLG glands are less affected by the oxidative damage induced by DM.


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