scholarly journals HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN OLDER ADULT SUBJECTS WITH KNEE OSTEOARTHRITIS PAIN

2021 ◽  
Vol 9 (5) ◽  
pp. 952-959
Author(s):  
Nimitha K.J ◽  
◽  
Bhupendra Singh ◽  
Radhey Shyam Gangwar ◽  
RN Srivastava ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Knee Osteoarthritis ◽  
Older Adult ◽  
Short Form ◽  
Health Related Quality ◽  
Osteoarthritis Pain ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

Aim of the study: The study aims to find the health-related quality of life (HRQoL) in older adult subjects with knee osteoarthritis pain. Material and methods: A cross-sectional, telephonic study was done on knee osteoarthritis subjects above 50 years of age. Socio-demographic scales and details,(ShalliBavoria, et al., 2020) i.e., WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index), SF-12 (Short Form survey), PHQ-9 (Patient Health Questionnaire) et al were applied( Soo-Hyun Park and Byeong-Hun Kang., 2020). Information was retrospectively compiled and a semi-structured proforma was selected to gather the clinical variables. Results: Results were identified by domains of Health related quality of life.Results showed that there is significant difference in general health related quality of life based on the KL grading of KOA.(P=0.02,P=0.04)Study concluded that general HRQoL worsens with higher grading of KOA.The results showed that there was a substantial discrepancy witnessed between males and females where females encountered more pain.As stiffness increases HRQoL decreases. More severity of pain was observed in depressed people.(Roger B. Fillingim, et al., 2020) Conclusion: Daily challenges and actions, of which some may be unusual to sufferers in a pastoral setting in India, underlie sedentary and effective strategies to Osteoarthritis and its control. The study concluded that a significant difference in pain and general quality of life-based on the KL grading of KOA (P=0.02, P=0.04) was observed.(Hye-Young Shim, etal, 2018) It was also found that there is a considerable difference in pain based on the duration of ]knee osteoarthritis (P=0.05).( Aliasghar A. Kiadalir, et al., 2017).

scholarly journals The impact of pain on functionality and health related quality of life in patients with knee osteoarthritis

2019 ◽  
Vol 147 (1-2) ◽  
pp. 45-51
Author(s):  
Aleksandra Jurisic-Skevin ◽  
Vesna Grbovic ◽  
Ivana Stankovic ◽  
Aleksandar Radunovic ◽  
Jasmin Nurkovic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Knee Osteoarthritis ◽  
Physical Functioning ◽  
Short Form ◽  
Health Related Quality ◽  
Knee Oa ◽  
Womac Questionnaire ◽  
Related Quality ◽  
Health Related

Introduction/Objective. Pain, stiffness and limited mobility are the main factors that lead to difficulties in performing daily activities and are also responsible for the decline in the quality of life in people with knee osteoarthritis (OA). The aim of this study was to evaluate the functional capacity and health related quality of life (HRQoL) compared to pain in patients with knee OA, as well as to determine the correlation between these three clinical variables. Methods. The study involved 931 patients diagnosed with knee OA. In all patients, pain was evaluated by a short form of the McGill pain questionnaire (SF-MPQ), functional status was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC), while life quality was evaluated using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Results. The average age of patients was 61.21 ? 4.62 years, while 71.3% of them were women. The quality of life in patients with knee OA and all pain parameters contained in the SF-MPQ were highly statistically positively associated (p ? 0.01). In addition, the physical functioning was mostly affected by emotional pain (rho = -0.585). A high statistical correlation (p ? 0.01) was noted between stiffness and physical functioning from the WOMAC questionnaire and all of the parameters from the SF-MPQ. The physical functioning from the WOMAC questionnaire had the strongest correlation with total pain incorporated into the McGill questionnaire (rho = 0.530). Conclusion. Knee pain has a significant impact on functional capacity and HRQoL in patients with knee OA. Therefore, one of the main therapy goals for OA of the knee should be to reduce the pain in the affected knee, which can help to improve the functionality and HRQoL of these patients.

scholarly journals Association of income and health-related quality of life in atrial fibrillation

Open Heart ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. e000974 ◽  
Author(s):  
Emily Guhl ◽  
Andrew Althouse ◽  
Michael Sharbaugh ◽  
Alexandra M Pusateri ◽  
Michael Paasche-Orlow ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Atrial Fibrillation ◽  
Daily Activity ◽  
Short Form ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

ObjectiveHealth-related quality of life (HRQoL) is a patient-centred benchmark promoted by clinical guidelines in atrial fibrillation (AF). Income is associated with health outcomes, but how income effects HRQoL in AF has limited investigation.MethodsWe enrolled a convenience cohort with AF receiving care at a regional healthcare system and assessed demographics, medical history, AF treatment, income, education and health literacy. We defined income as a categorical variable (<$20 000; $20 000–$49 999; $50 000–$99 999; >$100 000). We used two complementary HRQoL measures: (1) the atrial fibrillation effect on quality of life (AFEQT), measuring composite and domain scores (daily activity, symptoms, treatment concerns, treatment satisfaction; range 0–100); (2) the 12-item Short Form Survey (SF-12), measuring general HRQoL with physical and mental health domains (range 0–100). We related income to HRQoL and adjusted for relevant covariates.ResultsIn 295 individuals with AF (age 71±10, 40% women), we observed significant differences in HRQoL by income. Higher mean composite AFEQT scores were observed for higher income groups: participants with income <$20 000 had the lowest HRQoL (n=35, 68.2±21.4), and those with income >$100 000 had the highest HRQoL (n=64, 81.9±17.0; p=0.04). We also observed a significant difference by income in the AFEQT daily activity domain (p=0.02). Lower income was also associated with lower HRQoL in the mental health composite score of the SF-12 (59.7±21.5, income <$20 000 vs 79.3±16.3, income >$100 000; p<0.01).ConclusionWe determined that income was associated with HRQoL in a cohort with prevalent AF. Given the marked differences, we consider income as essential for understanding patient-centred outcomes in AF.

scholarly journals Effect of a Worksite Walking Competition on Health-Related Quality of Life Among University Employees

2015 ◽  
Vol 12 (3) ◽  
Author(s):  
Breanna Orozco ◽  
Lisa Leininger ◽  
Kendra Contente
Keyword(s):  
Quality Of Life ◽  
Health Promotion ◽  
Short Form ◽  
Control Group ◽  
Health Related Quality ◽  
University Employees ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

Worksite health promotion programs (WHPPs) aim to improve the health and wellness of employees in an effort to improve health related quality of life (HRQOL). The effect of exercise on improving HRQOL is well documented among clinical populations. However, few studies have examined the effect of WHPPs on HRQOL. The purpose of this study was to investigate the effect of a six-week “Workplace Walk-Off Competition” (WWC) on HRQOL among university employees. One hundred and nine university employees were included in this study (WWC group: n=47, Control group: n=62). All study participants completed the Short Form 12 Question, Version 2 (SF-12v2), a HRQOL questionnaire, before and after the WWC. The SF-12v2 questionnaire determines HRQOL based on two components and reports scores for a physical component summary (PCS) score and a mental component summary (MCS) score. A two-way repeated measures ANOVA was performed on PCS and MCS scores, followed by dependent t-tests for each group. There was no significant difference in PCS or MCS scores between the groups. Further, there were no statistically significant changes in PCS or MCS scores (p>.05) among either group, following the six-week WWC. Although much research deems WHPPs effective for improving many health indicators, this short-term program was not effective in improving PCS and MCS components of HRQOL. KEYWORDS: Quality of Life, Health Promotion, Walking Competition, University Employees

scholarly journals Impact of Polypharmacy on Health-Related Quality of Life in Dialysis Patients

2021 ◽  
pp. 1-10
Author(s):  
Julia M.T. Colombijn ◽  
Anna A. Bonenkamp ◽  
Anita van Eck van der Sluijs ◽  
Joost A. Bijlsma ◽  
Arnold H. Boonstra ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Self Rated Health ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
The Mean

<b><i>Introduction:</i></b> Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage coexisting comorbidities. However, some studies suggest that a large number of medications could also detrimentally affect patients’ health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of types of medications and HRQoL in dialysis patients. <b><i>Methods:</i></b> A multicentre cohort study was conducted among dialysis patients from Dutch dialysis centres 3 months after initiation of dialysis as part of the ongoing prospective DOMESTICO study. The number of types of medications, defined as the number of concomitantly prescribed types of drugs, was obtained from electronic patient records. Primary outcome was HRQoL measured with the Physical Component Summary (PCS) score and Mental Component Summary (MCS) score (range 0–100) of the Short Form 12. Secondary outcomes were number of symptoms (range 0–30) measured with the Dialysis Symptoms Index and self-rated health (range 0–100) measured with the EuroQol-5D-5L. Data were analysed using linear regression and adjusted for possible confounders, including comorbidity. Analyses for MCS and number of symptoms were performed after categorizing patients in tertiles according to their number of medications because assumptions of linearity were violated for these outcomes. <b><i>Results:</i></b> A total of 162 patients were included. Mean age of patients was 58 ± 17 years, 35% were female, and 80% underwent haemodialysis. The mean number of medications was 12.2 ± 4.5. Mean PCS and MCS were 36.6 ± 10.2 and 46.8 ± 10.0, respectively. The mean number of symptoms was 12.3 ± 6.9 and the mean self-rated health 60.1 ± 20.6. In adjusted analyses, PCS was 0.6 point lower for each additional medication (95% confidence interval [95% CI]: −0.9 to –0.2; <i>p</i> = 0.002). MCS was 4.9 point lower (95% CI: −8.8 to –1.0; <i>p</i> = 0.01) and 1.0 point lower (95% CI: −5.1–3.1; <i>p</i> = 0.63) for the highest and middle tertiles of medications, respectively, than for the lowest tertile. Patients in the highest tertile of medications reported 4.1 more symptoms than in the lowest tertile (95% CI: 1.5–6.6; <i>p</i> = 0.002), but no significant difference in the number of symptoms was observed between the middle and lowest tertiles. Self-rated health was 1.5 point lower for each medication (95% CI: −2.2 to –0.7; <i>p</i> &#x3c; 0.001). <b><i>Discussion/Conclusion:</i></b> After adjustment for comorbidity and other confounders, a higher number of medications were associated with a lower PCS, MCS, and self-rated health in dialysis patients and with more symptoms.

Association of Physical Morbidity and Health-Related Quality of Life in a Representative Sample of Older German People

2018 ◽  
Vol 25 (4) ◽  
pp. 140-151
Author(s):  
Markus A. Wirtz ◽  
Matthias Morfeld ◽  
Elmar Brähler ◽  
Andreas Hinz ◽  
Heide Glaesmer
Keyword(s):  
Quality Of Life ◽  
Representative Sample ◽  
Short Form ◽  
Physical Symptoms ◽  
German Population ◽  
Health Related Quality ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related

Abstract. The association between health-related quality of life (HRQoL; Short-Form Health Survey-12; SF-12) and patient-reported morbidity-related symptoms measured by the Patient Health Questionnaire-15 (PHQ-15) is analyzed in a representative sample of older people in the general German population. Data from 1,659 people aged 60 to 85 years were obtained. Latent class analysis identified six classes of patients, which optimally categorize clusters of physical symptoms the participants reported: musculoskeletal impairments (39.8%), healthy (25.7%), musculoskeletal and respiratory/cardiac impairments (12.8%), musculoskeletal and respiratory impairments, along with bowel and digestion problems (12.9%), general impairments (4.9%), and general impairments with no bowel and digestion problems (4.8%). The participants’ SF-12 Physical Health Scores (η2 = .39) and their Mental Health Scores (η2 = .28) are highly associated with these latent classes. These associations remain virtually identical after controlling for age. The results provide evidence that profiles of patient-reported physical impairments correspond strongly with reduced HRQoL independently from aging processes.

Factors Affecting Health-Related Quality of Life After the Arterial Switch Operation

2021 ◽  
Vol 12 (3) ◽  
pp. 344-351
Author(s):  
Julie Cleuziou ◽  
Anna-Katharina Huber ◽  
Martina Strbad ◽  
Masamichi Ono ◽  
Alfred Hager ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Arterial Switch Operation ◽  
Health Related Quality ◽  
Switch Operation ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Cardiac Medication

Background: Long-term morbidity and mortality outcomes of the arterial switch operation (ASO) in patients with transposition of the great arteries and Taussig-Bing anomaly are excellent. With an increasing number of patients reaching adolescence and adulthood, more attention is directed toward quality of life. Our study aimed to determine the health-related quality of life (hrQoL) outcomes in patients after the ASO and identify factors influencing their hrQoL. Methods: In this cross-sectional study, hrQoL of patients after ASO was assessed with the German version of the Short Form-36 (SF-36) and the potential association of specified clinical factors was analyzed. Patients of at least 14 years of age who underwent ASO in our institution from 1983 were considered eligible. Results: Of the 355 questionnaires sent to eligible patients, 261 (73%) were available for analysis. Compared to the reference population, patients who had undergone ASO had a significantly higher score in all subscales of the SF-36 except for vitality ( P < .01). Patients with an implanted pacemaker ( P = .002), patients who required at least one reoperation ( P < .001), and patients currently taking cardiac medication ( P < .004) or oral anticoagulation ( P = .036) had lower physical component scores compared to patients without these factors. Conclusions: Patients’ self-assessed and self-reported hrQoL after ASO (using German version of the Short Form 36) is very good. In this population, hrQoL is influenced by reoperation, the need for a pacemaker, and current cardiac medication or anticoagulant use. The development of strategies designed to mitigate or minimize the requirements for, and/or impact of these factors may lead to better hrQoL in this patient population.

Health-related quality of life with vertebral fracture, lumbar spondylosis and knee osteoarthritis in Japanese men: the ROAD study

2010 ◽  
Vol 5 (1-2) ◽  
pp. 91-99 ◽  
Author(s):  
Shigeyuki Muraki ◽  
Toru Akune ◽  
Hiroyuki Oka ◽  
Yoshio En-yo ◽  
Munehito Yoshida ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Vertebral Fracture ◽  
Knee Osteoarthritis ◽  
Health Related Quality ◽  
Japanese Men ◽  
The Road ◽  
Related Quality ◽  
Health Related ◽  
Road Study

Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing–remitting multiple sclerosis: findings from the CONFIRM study

2013 ◽  
Vol 20 (2) ◽  
pp. 253-257 ◽  
Author(s):  
Mariko Kita ◽  
Robert J Fox ◽  
J Theodore Phillips ◽  
Michael Hutchinson ◽  
Eva Havrdova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Short Form ◽  
Dimethyl Fumarate ◽  
Phase Iii ◽  
Health Related Quality ◽  
Relapsing Remitting ◽  
Related Quality ◽  
Health Related

Multiple sclerosis (MS) has a significant impact on health-related quality of life (HRQoL) with symptoms adversely affecting many aspects of everyday living. BG-12 (dimethyl fumarate) demonstrated significant efficacy in the phase III studies DEFINE and CONFIRM in patients with relapsing–remitting MS. In CONFIRM, HRQoL was worse in patients with greater disability at baseline, and who relapsed during the study, and improved with BG-12 treatment. Mean Short Form-36 Physical Component Summary scores for BG-12 increased over 2 years and scores for placebo decreased. Coupled with clinical and neuroradiological benefits, these HRQoL results further support BG-12 as an effective oral treatment for relapsing MS.

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