scholarly journals COMPARATIVE CLINICAL EVALUATION OF EFFICACY OF SYSTEMICALLY ADMINISTERED ANTIOXIDANT LYCOPENE (STARMUNE®) AND HERBAL (OXITARDTM) AS AN ADJUNCT TO SCALING AND ROOT PLANING IN PATIENTS WITH CHRONIC GINGIVITIS- A RANDOMIZED CLINICAL TRIAL

2020 ◽  
Vol 8 (7) ◽  
pp. 1058-1065
Author(s):  
Suvidha Uike ◽  
◽  
Rajvir Malik ◽  
Rashmi Bele ◽  
◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Clinical Evaluation ◽  
Scaling And Root Planing ◽  
Root Planing

scholarly journals Assessment of the Effect of Photodynamic Therapy on Treatment of Moderate-to-Severe Periodontitis; a Randomized Clinical Trial Study

2016 ◽  
Vol 9 (4) ◽  
pp. 83
Author(s):  
Babak Amoian ◽  
Aida Mirzaee ◽  
Seyed Mostafa Hosseini
Keyword(s):  
Clinical Trial ◽  
Photodynamic Therapy ◽  
Randomized Clinical Trial ◽  
Chronic Periodontitis ◽  
Time Interval ◽  
Clinical Parameters ◽  
Scaling And Root Planing ◽  
Bleeding On Probing ◽  
Treatment Groups ◽  
Root Planing

<p><strong>BACKGROUND &amp; AIM: </strong>Photodynamic therapy is a localized non-invasive treatment modality for the periodontal disease. Some evidences have shown that this technique is effective in improving the treatment outcome. This study compared the effects of photodynamic therapy with and without scaling and root planing and scaling and root planing alone on the clinical parameters of the chronic periodontitis.</p><p><strong>MATERIALS &amp; METHODS: </strong>In this single-blind, randomized clinical trial, 30 chronic periodontitis patients (10 for each modality) were selected and three different methods; photodynamic therapy alone (Group1) by FotoSan 630 system, scaling and root planning (SRP) alone (Group2), scaling and root planing combined with photodynamic therapy (Group3) were done for them randomly. Clinical parameters of probing pocket depth (PPD), bleeding on probing (BOP), and clinical attachment level (CAL) were measured at the baseline and 3, 6 and 12 weeks later. One-sided analysis of variance test was used to analyze PPD and CAL among the treatment groups in each time interval while the paired comparisons were carried out by employment of Dunnett’s test. The treatment groups were statically analyzed by the chi-square test regarding BOP. <strong></strong></p><p><strong>RESULTS: </strong>Before the treatment; no significant differences observed among treatment modalities regarding clinical parameters; while the differences were significant at three weeks (p&lt;0.0001 for PPD and CAL; p&lt;0.001 for BOP); six weeks (p&lt;0.0001 for PPD and CAL, p&lt;0.002 for BOP); and 12 weeks after the treatment (all: p&lt;0.0001). The least PPD and CAL values and the most frequency of non-bleeding on probing status were measured for PDT+SRP modality at three, six, and twelve weeks after the treatment.</p><p><strong>CONCLUSION: </strong>Photodynamic therapy supported the clinical parameters of periodontitis similar to SRP; however, PDT combined with SRP demonstrated a better result than that of SRP alone. Therefore, PDT combined with SRP can be used to improve outcomes of clinical parameters of periodontitis as compared to SRP alone in the short-term.</p>

Hyaluronic Acid as an Adjunct After Scaling and Root Planing: A Prospective Randomized Clinical Trial

2013 ◽  
Vol 84 (7) ◽  
pp. 941-949 ◽  
Author(s):  
Sigrun Eick ◽  
Antonio Renatus ◽  
Melanie Heinicke ◽  
Wolfgang Pfister ◽  
Stefan-Ioan Stratul ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Randomized Clinical Trial ◽  
Scaling And Root Planing ◽  
Prospective Randomized Clinical Trial ◽  
Root Planing

scholarly journals Efficacy of (−)-epigallocatechin gallate delivered by a new-type scaler tip during scaling and root planing on chronic periodontitis: a split-mouth, randomized clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yanfeng Wang ◽  
Jiajun Zeng ◽  
Qiao Yuan ◽  
Qingxian Luan
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Chronic Periodontitis ◽  
Combined Treatment ◽  
Epigallocatechin Gallate ◽  
Scaling And Root Planing ◽  
Clinical Trial Registry ◽  
Root Planing ◽  
New Type ◽  
And Control

Abstract Background (−)-Epigallocatechin Gallate (EGCG) as green tea catechins possessed antibacterial and anti-inflammatory effects on periodontal disease. This study was designed to evaluate the clinical and microbiological efficacy of scaling and root planing (SRP) using EGCG aqueous solution as coolants through a new-type ultrasonic scaler tip on chronic periodontitis. Methods This split-mouth, randomized clinical trial included 20 patients (2 drop-outs) with chronic periodontitis and the maxillary contra-lateral sides were allocated into test and control groups randomly. Through the new-type scaler tip, 762 sites with probing depth (PD) ≥ 4 mm were treated by SRP using EGCG solution or distilled water as coolants respectively. Clinical parameters and red complex pathogens in subgingival microbiome were evaluated at baseline, 3 and 6 months after treatments. Results During 6 months, the SRP plus EGCG medication contributed to additional PD reduction as 0.33 mm and gain of clinical attachment level as 0.3 mm compared with SRP alone, and approximate 8% more sites obtained PD reduction ≥ 2 mm (p < 0.05). Meanwhile, the mean relative abundance of Tannerella forsythia was significantly lower in the combined treatment group (p < 0.05). Conclusion The purified EGCG showed the potential to improve the outcome of periodontal non-surgical treatment and the new-type scaler tip provided an alternative vehicle for subgingival medication. Trial registration The trial was registered in Chinese Clinical Trial Registry on 15 February 2020 (No.: ChiCTR2000029831, retrospectively registered). http://www.chictr.org.cn/showprojen.aspx?proj=49441.

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