scholarly journals The Usefulness of the Combination of D-Dimer and Soluble Fibrin Monomer Complex for Diagnosis of Venous Thromboembolism in Psychiatric Practice: A Prospective Study

2021 ◽  
Vol Volume 17 ◽  
pp. 239-246
Author(s):  
Masahiro Takeshima ◽  
Hiroyasu Ishikawa ◽  
Masaya Ogasawara ◽  
Munehiro Komatsu ◽  
Dai Fujiwara ◽  
...  
2020 ◽  
Vol 18 (6) ◽  
pp. 1348-1356 ◽  
Author(s):  
Florian Posch ◽  
Julia Riedl ◽  
Eva‐Maria Reitter ◽  
Michael J. Crowther ◽  
Ella Grilz ◽  
...  

Neurology ◽  
2014 ◽  
Vol 82 (19) ◽  
pp. 1674-1677 ◽  
Author(s):  
M. Gladman ◽  
M. DeHaan ◽  
H. Pinto ◽  
W. Geerts ◽  
L. Zinman

Author(s):  
Ann Helen Kristoffersen ◽  
Per Hyltoft Petersen ◽  
Line Bjørge ◽  
Thomas Røraas ◽  
Sverre Sandberg

Background D-dimer increases during pregnancy and is problematic to use in the diagnosis of venous thromboembolism. Fibrin monomer represents an alternative biomarker for venous thromboembolism. However, to be useful in pregnancy, the fibrin monomer concentration should be stable throughout pregnancy and during postpartum. Methods To describe the course of fibrin monomer concentration during pregnancy and the postpartum period in healthy pregnant women and to compare their within-subject biological variation (CVI) with non-pregnant women. Blood samples were obtained every fourth week during pregnancy and three samples after delivery in 20 healthy women and every fourth week during a 40-week period in 19 healthy non-pregnant women. Fibrin monomer (STA Liatest FM, Stago) was analysed in duplicates for all samples. Concentrations of fibrin monomer in pregnant and non-pregnant women were compared and the CVI for fibrin monomer was calculated. Results The median fibrin monomer concentration in pregnant women was 6.2 mg/L (2.5 and 97.5 percentiles 3.7–10.8 mg/L) and in non-pregnant women 4.8 mg/L (3.6–8.2) ( P < 0.01). The fibrin monomer concentration was relatively stable during pregnancy, although a few unexplained high fibrin monomer concentrations were found during pregnancy/postpartum. Fibrin monomer CVI in pregnancy and postpartum was 20.6% (95% CI 18.3, 23.5) and in non-pregnant 16.1% (13.7, 18.9). Conclusions For clinical purposes, fibrin monomer concentration can be considered stable during pregnancy, although it is slightly higher than in non-pregnant women. Pregnant and non-pregnant women have the same CVI. The suitability of fibrin monomer in venous thromboembolism diagnosis in pregnant women should be validated in further studies.


2019 ◽  
Vol 3 (1) ◽  
pp. 26-30
Author(s):  
Shozo Yano ◽  
Yuri Yoshida ◽  
Yasuko Notsu ◽  
Asako Fukuma ◽  
Eri Nitta ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0238216 ◽  
Author(s):  
Alberto Alonso-Fernández ◽  
Nuria Toledo-Pons ◽  
Borja G. Cosío ◽  
Aina Millán ◽  
Néstor Calvo ◽  
...  

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