scholarly journals Dynamic assessment of venous thromboembolism risk in patients with cancer by longitudinal D‐Dimer analysis: A prospective study

2020 ◽  
Vol 18 (6) ◽  
pp. 1348-1356 ◽  
Author(s):  
Florian Posch ◽  
Julia Riedl ◽  
Eva‐Maria Reitter ◽  
Michael J. Crowther ◽  
Ella Grilz ◽  
...  
2021 ◽  
Vol Volume 17 ◽  
pp. 239-246
Author(s):  
Masahiro Takeshima ◽  
Hiroyasu Ishikawa ◽  
Masaya Ogasawara ◽  
Munehiro Komatsu ◽  
Dai Fujiwara ◽  
...  

2007 ◽  
Vol 264 (6) ◽  
pp. 651-657 ◽  
Author(s):  
Pepijn A. Borggreven ◽  
Irma M. Verdonck-de Leeuw ◽  
Martin J. Muller ◽  
Milou L. C. H. Heiligers ◽  
Remco de Bree ◽  
...  

Neurology ◽  
2014 ◽  
Vol 82 (19) ◽  
pp. 1674-1677 ◽  
Author(s):  
M. Gladman ◽  
M. DeHaan ◽  
H. Pinto ◽  
W. Geerts ◽  
L. Zinman

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0238216 ◽  
Author(s):  
Alberto Alonso-Fernández ◽  
Nuria Toledo-Pons ◽  
Borja G. Cosío ◽  
Aina Millán ◽  
Néstor Calvo ◽  
...  

2017 ◽  
Vol 13 (7) ◽  
pp. e613-e622 ◽  
Author(s):  
Allan Ramos-Esquivel ◽  
Álvaro Víquez-Jaikel ◽  
Cristina Fernández

Purpose: Patients with cancer frequently use herbal supplements and concomitant medications along with antineoplastic agents. These patients are at high risk of herb-drug interactions (HDIs) and drug-drug interactions (DDIs). We aimed to determine clinically relevant DDIs and HDIs leading to pharmaceutical intervention. Methods: Patients starting a new anticancer therapy were asked to complete a questionnaire to identify concomitant use of any over-the-counter drug or herbal supplement. Potential DDIs and HDIs were identified using two different databases. If a potentially clinically relevant DDI was recognized by the clinical pharmacist, a notification was sent to the prescribing oncologist, who decided whether to carry out a suggested intervention. Regression analyses were performed to identify variables associated with clinically relevant DDIs. Results: A total of 149 patients were included in this study, with 36 potentially clinically relevant DDIs identified in 26 patients (17.4%; 95% CI, 11.3% to 23.5%), all of them leading to therapy modifications. In total, four patients (2.7%; 95% CI, 0.1% to 5.3%) had experienced clinical consequences from DDIs at the time of pharmacist notification. Additionally, 84 patients (56.4%; 95% CI, 48.4% to 64.4%) reported using concurrent herbal supplements, and 122 possible HDIs were detected. Concomitant use of two or more drugs was independently associated with high risk of a clinically significant DDI (odds ratio, 2.53; 95% CI, 1.08 to 5.91; P = .03). Conclusion: Potentially clinically relevant DDIs and possible HDIs were frequently detected in this prospective study. A multidisciplinary approach is required to identify and avoid potentially harmful combinations with anticancer therapy.


Author(s):  
Joana Duarte ◽  
Ana Tavares e Castro ◽  
Raquel Silva ◽  
Lurdes Correia ◽  
Adélia Simão ◽  
...  

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