scholarly journals Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data

2018 ◽  
Vol Volume 12 ◽  
pp. 153-161 ◽  
Author(s):  
Natacha Biset ◽  
Mélanie Lelubre ◽  
Christelle Senterre ◽  
Karim Amighi ◽  
Olivier Bugnon ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Community Pharmacies ◽  
Pharmacy Refill

Effectiveness of a web-based medication adherence tool with patient centered communication: Results of a clustered randomized controlled trial (Preprint)

2019 ◽  
Author(s):  
Jan van Lieshout ◽  
Joyca Lacroix ◽  
Aart van Halteren ◽  
Martina Teichert
Keyword(s):  
Randomized Controlled Trial ◽  
Medication Adherence ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Community Pharmacies ◽  
Web Based ◽  
Randomized Controlled ◽  
Tailored Interventions ◽  
Increased Risk

BACKGROUND Growing numbers of people use medication for chronic conditions; non-adherence is common, leading to poor disease control. A newly developed web-based tool to identify an increased risk for non-adherence with related potential individual barriers might facilitate tailored interventions and improve adherence. OBJECTIVE To assess the effectiveness of the newly developed tool to improve medication adherence. METHODS A cluster randomized controlled trial assessed the effectiveness of this adherence tool in patients initiating cardiovascular or oral blood glucose lowering medication. Participants were included in community pharmacies. They completed an online questionnaire comprising an assessments of their risk for medication non-adherence and subsequently of barriers to adherence. In pharmacies belonging to the intervention group, individual barriers displayed in a graphical profile on a tablet were discussed by pharmacists and patients at high non-adherence risk in face to face meetings and shared with their general practitioners and practice nurses. Tailored interventions were initiated by the healthcare providers. Barriers of control patients were not presented or discussed and these patients received usual care. The primary outcome was the difference in medication adherence at 8 months follow-up between patients with an increased non-adherence risk from intervention and control group, calculated from dispensing data. RESULTS Data from 492 participants in 15 community pharmacies were available for analyses (intervention 253, 7 pharmacies; control 239, 8 pharmacies). The intervention had no effect on medication adherence (-0.01; 95%CI -0.59 – 0.57; P= .96), neither in the post hoc per protocol analysis (0.19; 95%CI -0.50 – 0.89; P=.58). CONCLUSIONS This study showed no effectiveness of a risk stratification and tailored intervention addressing personal barriers for medication adherence. Various potential explanations for lack of effect were identified. These explanations relate for instance to high medication adherence in the control group, study power and fidelity. Process evaluation should elicit possible improvements and inform the redesign of intervention and implementation. CLINICALTRIAL The Netherlands National Trial Register: NTR5186. Date: May 18, 2015 (http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=5186)

scholarly journals Implicit and Explicit Attitudes Toward Antihypertensive Medications Explain Variation in Pharmacy Refill and Self‐Reported Adherence Beyond Traditional Risk Factors: Potential Novel Mechanism Underlying Adherence

2021 ◽  
Author(s):  
Leslie S. Craig ◽  
Erin Peacock ◽  
Brice L. Mohundro ◽  
Julia H. Silver ◽  
James Marsh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medication Adherence ◽  
Social Determinants Of Health ◽  
Social Determinants ◽  
Antihypertensive Medication ◽  
Explicit Attitudes ◽  
Pharmacy Refill ◽  
Traditional Risk Factors ◽  
Implicit And Explicit ◽  
Implicit And Explicit Attitudes

Background In pursuit of novel mechanisms underlying persistent low medication adherence rates, we assessed contributions of implicit and explicit attitudes, beyond traditional risk factors, in explaining variation in objective and subjective antihypertensive medication adherence. Methods and Results Implicit and explicit attitudes were assessed using the difference scores from the computer‐based Single Category Implicit Association Test and the Necessity and Concerns subscales of the Beliefs about Medicines Questionnaire, respectively. Antihypertensive medication adherence was measured using pharmacy refill proportion of days covered (PDC: mean PDC, low PDC <0.8) and the self‐report 4‐item Krousel‐Wood Medication Adherence Scale (K‐Wood‐MAS‐4: mean K‐Wood‐MAS‐4, low adherence via K‐Wood‐MAS‐4 ≥1). Hierarchical logistic and linear regression models controlled for traditional risk factors including social determinants of health, explicit, and implicit attitudes in a stepwise fashion. Community‐dwelling insured participants (n=85: 44.7% female; 20.0% Black; mean age, 62.3 years; 43.5% low PDC, and 31.8% low adherence via K‐Wood‐MAS‐4) had mean (SD) explicit and implicit attitude scores of 7.188 (5.683) and 0.035 (0.334), respectively. Low PDC was inversely associated with more positive explicit (adjusted odds ratio [aOR], 0.87; 95% CI, 0.78–0.98; P =0.022) and implicit (aOR, 0.12; 95% CI, 0.02–0.80; P =0.029) attitudes, which accounted for an additional 8.6% ( P =0.016) and 6.5% ( P =0.029) of variation in low PDC, respectively. Lower mean K‐Wood‐MAS‐4 scores (better adherence) were associated only with more positive explicit attitudes (adjusted β, −0.04; 95% CI, −0.07 to −0.01; P =0.026); explicit attitudes explained an additional 5.6% ( P =0.023) of K‐Wood‐MAS‐4 variance. Conclusions Implicit and explicit attitudes explained significantly more variation in medication adherence beyond traditional risk factors, including social determinants of health, and should be explored as potential mechanisms underlying adherence behavior.

scholarly journals Implementation of an interprofessional medication adherence program for chronic patients in community pharmacies: how much does it cost for the provider?

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Clemence Perraudin ◽  
Jean-François Locca ◽  
Christophe Rossier ◽  
Olivier Bugnon ◽  
Marie-Paule Schneider
Keyword(s):  
Medication Adherence ◽  
Community Pharmacies ◽  
Chronic Patients

scholarly journals Effects of Emotional Response on Adherence to Antihypertensive Medication and Blood Pressure Improvement

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Robert D. Keeley ◽  
Margaret Driscoll
Keyword(s):  
Blood Pressure ◽  
Medication Adherence ◽  
Emotional Response ◽  
Antihypertensive Medication ◽  
Primary Outcome ◽  
Secondary Outcome ◽  
Behavioral Risk ◽  
Improve Medication Adherence ◽  
Pharmacy Refill ◽  
Adherence Score

Background. Developing interventions to improve medication adherence may depend upon discovery of novel behavioral risk factors for nonadherence.Objective. Explore the effects of emotional response (ER) on adherence to antihypertensive medication and on systolic blood pressure (SBP) improvement.Design. We studied 101 adults with diabetes and hypertension. The primary outcome, 90-day “percentage of days covered” adherence score, was determined from pharmacy refill records. The secondary outcome was change in SBP over 90 days. ER was classified as positive, negative, or neutral.Results. Average adherence was 71.6% (SD 31.4%), and negative and positive ER were endorsed by 25% and 9% of subjects, respectively. Gender moderated the effect of positive or negative versus neutral ER on adherence (interactionP=0.003); regardless of gender, negative and positive ER were associated with similarly high and low adherence, respectively, but males endorsing neutral ER had significantly higher adherence than their female counterparts (85.6% versus 57.1%,Fvalue = 15.3,P=0.0002). Adherence mediated ER's effect on SBP improvement: among participants with negative, but not positive or neutral, ER, increasing adherence and SBP improvement were correlated (Spearman’sr=0.49,P=0.02).Conclusions. Negative, but not positive or neutral, ER predicted better medication adherence and a correlation between medication adherence and improvement in SBP.

scholarly journals Factors Related to Medication Adherence of Cognitively Impaired Patients in Community Pharmacies

2012 ◽  
Vol 03 (03) ◽  
pp. 368-380 ◽  
Author(s):  
Yoko Nanaumi ◽  
Mitsuko Onda ◽  
Yusuke Mukai ◽  
Rie Tanaka ◽  
Kenichi Tubota ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Cognitively Impaired ◽  
Community Pharmacies

Quantifying Glaucoma Medication Adherence: The Relationship Between Self-Report, Electronic Monitoring, and Pharmacy Refill

2016 ◽  
Vol 32 (6) ◽  
pp. 346-354 ◽  
Author(s):  
Jaya B. Kumar ◽  
Hayden B. Bosworth ◽  
Betsy Sleath ◽  
Sandra Woolson ◽  
Maren Olsen ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Electronic Monitoring ◽  
Self Report ◽  
Glaucoma Medication ◽  
Pharmacy Refill ◽  
The Relationship

scholarly journals P008 Measuring medicines adherence in children: a systematic review

2019 ◽  
Vol 104 (7) ◽  
pp. e2.10-e2
Author(s):  
Mohammed Aldosari ◽  
Sharon Conroy ◽  
Ana Oliveira
Keyword(s):  
Systematic Review ◽  
Medication Adherence ◽  
Mobile Phone ◽  
Plasma Levels ◽  
Self Report ◽  
Cochrane Library ◽  
List Type ◽  
Inclusion Criteria ◽  
Advantages And Disadvantages ◽  
Pharmacy Refill

Aim30–70% of children prescribed long-term medicines have poor adherence.1 Knowing the degree of adherence is important to understand the consequences of nonadherence and to develop strategies to improve medication adherence in children. We therefore performed a systematic review to identify measures of medication adherence used in children and the strengths and weaknesses of those measures.MethodsA systematic literature search was performed using PubMed, EMBASE, Medline, CINAHL, IPA and Cochrane library databases covering the period March 2008 to March 2018 in order to focus on the methods recently used to assess adherence. Inclusion criteria were original research studies measuring medication adherence in children (aged 0–18 years) and included all countries and languages. To be included, the assessment tool used to measure adherence in each study needed to be described in detail. Exclusion criteria included: review articles, editorials, conference papers, reports, and studies reporting only adherence outcomes/rates without reporting measurement methods. As a reliability measure, 5% of titles and abstracts were assessed independently by a second researcher.ResultsOf 9,747 papers identified by the search, only 31 articles met the inclusion criteria. Most studies were conducted in the US (14) with four in South Africa, three in Kenya and the remaining ten studies in various countries including one in the UK. Diseases studied included: HIV/AIDS (13), asthma (5), inflammatory bowel disease (3), epilepsy (2), type 1 diabetes (2), others (6). In the commonest disease studied, HIV, self-report, Medication Event Monitoring Systems (MEMS), dose counting, pharmacy refill data and medication plasma levels were used to assess adherence. In patients with diabetes, mobile phone, medication plasma levels and self-report were used. Canister weight and MEMS were used to assess adherence in patients with asthma. Self- reporting was the most commonly used method to assess adherence and was reported to be flexible, inexpensive, and time saving but it was the least accurate and overestimated adherence rates. MEMS was the most accurate method but was also the most expensive. Dose counting was easy to use and inexpensive but adherence was also overestimated with this method. Measuring medication plasma levels was more precise than self-reporting and dose counting but was costly, time consuming and difficult to perform. Pharmacy refill data was more accurate than self-reporting and less accurate than MEMS and medication plasma levels. Mobile phone methods were reported to be very expensive and difficult to perform. Canister weight had the same efficacy as using MEMS and was less expensive, but was only applicable to inhalation devices. ConclusionCurrently, no gold standard method to measure adherence to medicines in children exists as each method has its own advantages and disadvantages. Overall, the MEMS method was the most accurate but most expensive, while self-reporting was the least accurate but least costly.None of these measures were reported to be highly accurate in the assessment of adherence, so it is important to use a combination of multiple measures in order to gain a true picture of adherence.ReferenceChappell F. Medication adherence in children remains a challenge. Prescriber 2015;26(12):31–4.

scholarly journals Impact of Pharmacists’ Interventions and Patients’ Decision on Health Outcomes in Terms of Medication Adherence and Quality Use of Medicines among Patients Attending Community Pharmacies: A Systematic Review

2021 ◽  
Vol 18 (9) ◽  
pp. 4392
Author(s):  
Kingston Rajiah ◽  
Shreeta Sivarasa ◽  
Mari Kannan Maharajan
Keyword(s):  
Medication Adherence ◽  
Health Outcomes ◽  
Systematic Reviews ◽  
Effective Interaction ◽  
Self Care ◽  
Community Pharmacists ◽  
Community Pharmacies ◽  
Quality Use Of Medicines ◽  
The Impact ◽  
Decision Choice

Community pharmacists are responsible for providing the appropriate information on the use of medications to patients, which may enhance their medication adherence. The extent of control that patients have on their health care preferences creates many challenges for community pharmacists. This study aimed to determine the impact of pharmacist interventions and patient decisions on health outcomes concerning medication adherence and the quality use of medicines among patients attending community pharmacies. Appropriate studies were identified in a systematic search using the databases of Medline, Scopus, Google Scholar, and PubMed. The search included literature published between 2004 and 2019. The database searches yielded 683 titles, of which 19 studies were included after the full-text analysis with a total of 9313 participants. Metaprop command in Stata software version 14 was used for the analysis. This study was undertaken based on the general principles of the Cochrane Handbook for Systematic Reviews of Interventions and subsequently reported according to the Preferred Reporting Items for Systematic Reviews (PRISMA) extension. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach was directly used to rate the quality of evidence (high, moderate, low, or very low). The results revealed the effective interaction between patients and community pharmacists, the importance of pharmacist intervention on medication adherence and quality use of medicine, and the role of community pharmacists in counselling patients. Decision/choice of patients in self-care and self-medication is a factor contributing to health outcomes. Effective interaction of community pharmacists with patients in terms of medication adherence and quality use of medicines provided a better health outcome among patients. The community pharmacists influenced the decision/choice of patients in self-care and self-medications.

scholarly journals Association between Asthma Medication Adherence and Patient-Provider Collaboration

2019 ◽  
Vol 20 (2) ◽  
Author(s):  
Lauren Lockwood
Keyword(s):  
Medication Adherence ◽  
Asthma Management ◽  
Health Concern ◽  
Asthma Morbidity ◽  
Pharmacy Refill ◽  
The Family ◽  
Adherence Data ◽  
The Relationship ◽  
Pearson Correlations ◽  
Subjective Reports

Asthma is a significant pediatric public health concern, with 8.3% of children in the U.S. diagnosed with asthma. Pediatric asthma morbidity is consistently linked to medication non-adherence. Medication adherence has been shown to be influenced by patient-provider interactions. The aim of this study is to examine the relationship between medication adherence, using both objective and subjective reports, to patient-provider collaboration in adolescents with poorly controlled asthma. Thirty adolescents ages 12 to 15 were interviewed along with their caregivers using the Family Asthma Management System Scale (FAMSS). Adherence data were collected via pharmacy refill reports and scores on the FAMSS adherence rating subscale. Patient-provider collaboration was assessed using the corresponding subscale from the FAMSS interview. Pearson correlations were conducted to examine the relationships between both measures of adherence and patient-provider collaboration. There was no significant association between adherence measured with pharmacy refills and patient-provider collaboration (r = .27, p = .176). A significant correlation was found between medication adherence, as measured by the FAMSS ratings, and patient-provider collaboration (r = .53, p = .003). These findings suggest that more collaborative patient-provider relationships may be linked to higher medication adherence among adolescents with poorly controlled asthma.

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