Quantifying Glaucoma Medication Adherence: The Relationship Between Self-Report, Electronic Monitoring, and Pharmacy Refill

2016 ◽  
Vol 32 (6) ◽  
pp. 346-354 ◽  
Author(s):  
Jaya B. Kumar ◽  
Hayden B. Bosworth ◽  
Betsy Sleath ◽  
Sandra Woolson ◽  
Maren Olsen ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Electronic Monitoring ◽  
Self Report ◽  
Glaucoma Medication ◽  
Pharmacy Refill ◽  
The Relationship

scholarly journals P008 Measuring medicines adherence in children: a systematic review

2019 ◽  
Vol 104 (7) ◽  
pp. e2.10-e2
Author(s):  
Mohammed Aldosari ◽  
Sharon Conroy ◽  
Ana Oliveira
Keyword(s):  
Systematic Review ◽  
Medication Adherence ◽  
Mobile Phone ◽  
Plasma Levels ◽  
Self Report ◽  
Cochrane Library ◽  
List Type ◽  
Inclusion Criteria ◽  
Advantages And Disadvantages ◽  
Pharmacy Refill

Aim30–70% of children prescribed long-term medicines have poor adherence.1 Knowing the degree of adherence is important to understand the consequences of nonadherence and to develop strategies to improve medication adherence in children. We therefore performed a systematic review to identify measures of medication adherence used in children and the strengths and weaknesses of those measures.MethodsA systematic literature search was performed using PubMed, EMBASE, Medline, CINAHL, IPA and Cochrane library databases covering the period March 2008 to March 2018 in order to focus on the methods recently used to assess adherence. Inclusion criteria were original research studies measuring medication adherence in children (aged 0–18 years) and included all countries and languages. To be included, the assessment tool used to measure adherence in each study needed to be described in detail. Exclusion criteria included: review articles, editorials, conference papers, reports, and studies reporting only adherence outcomes/rates without reporting measurement methods. As a reliability measure, 5% of titles and abstracts were assessed independently by a second researcher.ResultsOf 9,747 papers identified by the search, only 31 articles met the inclusion criteria. Most studies were conducted in the US (14) with four in South Africa, three in Kenya and the remaining ten studies in various countries including one in the UK. Diseases studied included: HIV/AIDS (13), asthma (5), inflammatory bowel disease (3), epilepsy (2), type 1 diabetes (2), others (6). In the commonest disease studied, HIV, self-report, Medication Event Monitoring Systems (MEMS), dose counting, pharmacy refill data and medication plasma levels were used to assess adherence. In patients with diabetes, mobile phone, medication plasma levels and self-report were used. Canister weight and MEMS were used to assess adherence in patients with asthma. Self- reporting was the most commonly used method to assess adherence and was reported to be flexible, inexpensive, and time saving but it was the least accurate and overestimated adherence rates. MEMS was the most accurate method but was also the most expensive. Dose counting was easy to use and inexpensive but adherence was also overestimated with this method. Measuring medication plasma levels was more precise than self-reporting and dose counting but was costly, time consuming and difficult to perform. Pharmacy refill data was more accurate than self-reporting and less accurate than MEMS and medication plasma levels. Mobile phone methods were reported to be very expensive and difficult to perform. Canister weight had the same efficacy as using MEMS and was less expensive, but was only applicable to inhalation devices. ConclusionCurrently, no gold standard method to measure adherence to medicines in children exists as each method has its own advantages and disadvantages. Overall, the MEMS method was the most accurate but most expensive, while self-reporting was the least accurate but least costly.None of these measures were reported to be highly accurate in the assessment of adherence, so it is important to use a combination of multiple measures in order to gain a true picture of adherence.ReferenceChappell F. Medication adherence in children remains a challenge. Prescriber 2015;26(12):31–4.

scholarly journals Association between Asthma Medication Adherence and Patient-Provider Collaboration

2019 ◽  
Vol 20 (2) ◽  
Author(s):  
Lauren Lockwood
Keyword(s):  
Medication Adherence ◽  
Asthma Management ◽  
Health Concern ◽  
Asthma Morbidity ◽  
Pharmacy Refill ◽  
The Family ◽  
Adherence Data ◽  
The Relationship ◽  
Pearson Correlations ◽  
Subjective Reports

Asthma is a significant pediatric public health concern, with 8.3% of children in the U.S. diagnosed with asthma. Pediatric asthma morbidity is consistently linked to medication non-adherence. Medication adherence has been shown to be influenced by patient-provider interactions. The aim of this study is to examine the relationship between medication adherence, using both objective and subjective reports, to patient-provider collaboration in adolescents with poorly controlled asthma. Thirty adolescents ages 12 to 15 were interviewed along with their caregivers using the Family Asthma Management System Scale (FAMSS). Adherence data were collected via pharmacy refill reports and scores on the FAMSS adherence rating subscale. Patient-provider collaboration was assessed using the corresponding subscale from the FAMSS interview. Pearson correlations were conducted to examine the relationships between both measures of adherence and patient-provider collaboration. There was no significant association between adherence measured with pharmacy refills and patient-provider collaboration (r = .27, p = .176). A significant correlation was found between medication adherence, as measured by the FAMSS ratings, and patient-provider collaboration (r = .53, p = .003). These findings suggest that more collaborative patient-provider relationships may be linked to higher medication adherence among adolescents with poorly controlled asthma.

A Scoping Review of Methods Used to Assess Medication Adherence in Patients with Chronic Conditions

2021 ◽  
Author(s):  
Pinelopi Konstantinou ◽  
Orestis Kasinopoulos ◽  
Christiana Karashiali ◽  
Geοrgios Georgiou ◽  
Andreas Panayides ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Quality Indicators ◽  
Scoping Review ◽  
Chronic Conditions ◽  
Electronic Monitoring ◽  
Intervention Development ◽  
Assessment Methods ◽  
Self Report ◽  
Evidence Based ◽  
Gold Standard Method

Abstract Background Medication nonadherence of patients with chronic conditions is a complex phenomenon contributing to increased economic burden and decreased quality of life. Intervention development relies on accurately assessing adherence but no “gold standard” method currently exists. Purpose The present scoping review aimed to: (a) review and describe current methods of assessing medication adherence (MA) in patients with chronic conditions with the highest nonadherence rates (asthma, cancer, diabetes, epilepsy, HIV/AIDS, hypertension), (b) outline and compare the evidence on the quality indicators between assessment methods (e.g., sensitivity), and (c) provide evidence-based recommendations. Methods PubMed, PsycINFO and Scopus databases were screened, resulting in 62,592 studies of which 71 met criteria and were included. Results Twenty-seven self-report and 10 nonself-report measures were identified. The Medication Adherence Report Scale (MARS-5) was found to be the most accurate self-report, whereas electronic monitoring devices such as Medication Event Monitoring System (MEMS) corresponded to the most accurate nonself-report. Higher MA rates were reported when assessed using self-reports compared to nonself-reports, except from pill counts. Conclusions Professionals are advised to use a combination of self-report (like MARS-5) and nonself-report measures (like MEMS) as these were found to be the most accurate and reliable measures. This is the first review examining self and nonself-report methods for MA, across chronic conditions with the highest nonadherence rates and provides evidence-based recommendations. It highlights that MA assessment methods are understudied in certain conditions, like epilepsy. Before selecting a MA measure, professionals are advised to inspect its quality indicators. Feasibility of measures should be explored in future studies as there is presently a lack of evidence.

Abstract P180: Time to Screen for Medication Non-Adherence in Patients with Uncontrolled Hypertension? Comparing the Test Properties of Two Commonly Used Self-Report Adherence Questionnaires

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Ian M Kronish ◽  
Benjamin Gallagher ◽  
Siqin Ye ◽  
Donald Edmondson
Keyword(s):  
Medication Adherence ◽  
Gold Standard ◽  
Electronic Monitoring ◽  
Negative Likelihood Ratio ◽  
Self Report ◽  
Uncontrolled Hypertension ◽  
Care Practice ◽  
Sensitivity Specificity ◽  
Perfect Adherence ◽  
Poor Medication Adherence

Introduction: One major cause of uncontrolled hypertension is poor medication adherence. Yet, clinicians are poor at judging adherence and the gold standard for measuring medication adherence - electronic monitoring - is rarely available in clinic settings. Self-report adherence questionnaires, by contrast, are free, simple to administer, and may be useful for screening. Hypothesis: To compare the test properties of the Morisky Medication Adherence Questionnaire (MMAQ) and the Visual Analog Scale (VAS) for diagnosing non-adherence in patients with uncontrolled hypertension, using electronic pillbox monitoring as the gold standard. Methods: Thus far, 48 patients with uncontrolled hypertension [BP ≥140/90 mmHg (or ≥130/80 mmHg if diabetic) on 2 serial clinic visits] have been enrolled during visits to a hospital-based primary care practice. Patients are asked to take up to 4 of their BP medications from a 4-bin electronic pillbox (MedSignals) that records the date and time each bin is opened. At the next visit, patients complete the MMAQ, comprised of 8 brief questions that assess pill-taking behavior. The MMAQ is scored from 0 to 8; 8 signifies perfect adherence. Patients also complete the VAS by marking an “X” on a line from 0% to 100% to indicate how often they took each of their BP medications. Sensitivity, specificity, and negative likelihood ratio (NLR) were assessed for each test. The gold standard for adherence was ≥ 80% adherence averaged across each of the electronically monitored medications. Results: Mean age is 62 years (range 34 [[Unable to Display Character: –]] 83), 70% women, 62% Hispanic, 52% Black, and 50% with diabetes. Mean BP at enrollment was 160/88 mmHg. Patients were prescribed a mean (SD) of 2.6 (0.9) BP medications. Adherence was monitored for 41 +/- 23 days. Mean adherence by electronic monitoring was 78% (range 13%-100%); 42% were adherent (≥ 80%) by the gold standard. Using a cutpoint of 7.5 (67% of the sample were below this cutpoint), the MMAQ has a sensitivity of 94% and specificity of 54%, corresponding to a NLR of 0.10 (95%CI 0.01 to 0.67). Using a cutpoint of 80% (only 11% of the sample below this cutpoint), the VAS has a sensitivity of 28%, specificity of 67%, and a NLR of 0.72. Conclusions: The MMAQ, but not the VAS, is a sensitive tool for screening for non-adherence in patients with uncontrolled hypertension and may be useful for excluding medication non-adherence as the cause of uncontrolled hypertension for a large proportion of patients.

scholarly journals The Relationship between Glaucoma Medication Adherence, Eye Drop Technique, and Visual Field Defect Severity

Ophthalmology ◽  
2011 ◽  
Vol 118 (12) ◽  
pp. 2398-2402 ◽  
Author(s):  
Betsy Sleath ◽  
Susan Blalock ◽  
David Covert ◽  
Jennifer L. Stone ◽  
Asheley Cockrell Skinner ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Visual Field ◽  
Visual Field Defect ◽  
Glaucoma Medication ◽  
The Relationship ◽  
Field Defect ◽  
Drop Technique

The Relationship of Self-Report and Medication Possession With Glaucoma Medication Administration Success

2019 ◽  
Vol 28 (3) ◽  
pp. e46-e48
Author(s):  
Aaron M. Hein ◽  
Jullia A. Rosdahl ◽  
Hayden B. Bosworth ◽  
Sandra L. Woolson ◽  
Maren K. Olsen ◽  
...  
Keyword(s):  
Medication Administration ◽  
Self Report ◽  
Glaucoma Medication ◽  
Relationship Of ◽  
The Relationship

scholarly journals Examination of Transition Readiness, Medication Adherence, and Resilience in Pediatric Chronic Illness Populations: A Pilot Study

2020 ◽  
Vol 17 (6) ◽  
pp. 1905 ◽  
Author(s):  
Tanvi Verma ◽  
Jennifer Rohan
Keyword(s):  
Medication Adherence ◽  
Chronic Illness ◽  
Transition To Adulthood ◽  
Strong Relationship ◽  
Transition To Adult Care ◽  
Adult Care ◽  
Transition Readiness ◽  
Pharmacy Refill ◽  
Resilience Scale ◽  
The Relationship

The present study assessed the relationship between resilience, adherence, and transition readiness in adolescents/young adults with chronic illness. Participants included 50 patients (Mean age, Mage = 17.3 ± 2.1 years) diagnosed with an oncology disorder (n = 7; 12.1%), hematology disorder (n = 5; 8.6%), nephrology disorder (n = 31; 53.4%), or rheumatology disorder (n = 7; 12.1%). Patients were administered questionnaires assessing resilience (Conner–Davidson Resilience Scale 25-item questionnaire, CD-RISC-25), transition readiness (Self-Management and Transition to Adulthood with Rx=Treatment, STARx), and self-reported medication adherence (Medication Adherence Module, MAM). Medical chart reviews were conducted to determine objective medication adherence rates based on pharmacy refill history (medication adherence ratios). A multivariate correlation analysis was used to examine the relationship between resilience, transition readiness, and adherence. There was a moderate relationship (r = 0.34, p ≤ 0.05) between resilience (M = 74.67 ± 13.95) and transition readiness (M = 67.55 ± 8.20), such that more resilient patients reported increased readiness to transition to adult care. There also was a strong relationship (r = 0.80, p ≤ 0.01) between self-reported medication adherence (M = 86.27% ± 15.98) and pharmacy refill history (Mean Medication Adherence Ratio, MMAR = 0.75 ± 0.27), which indicated that self-reported adherence was consistent with prescription refill history across pediatric illness cohorts. Our findings underscore the importance of assessing resilience, transition readiness, and adherence years before transitioning pediatric patients to adult providers to ensure an easier transition to adult care.

scholarly journals Impact of Once- Versus Twice-Daily Tacrolimus Dosing on Medication Adherence in Stable Renal Transplant Recipients: A Canadian Single-Center Randomized Controlled Trial

2019 ◽  
Vol 6 ◽  
pp. 205435811986799 ◽  
Author(s):  
Theone S. E. Paterson ◽  
Maryam Demian ◽  
Rebecca Jean Shapiro ◽  
Wendy Loken Thornton
Keyword(s):  
Medication Adherence ◽  
Renal Transplant ◽  
Electronic Monitoring ◽  
Self Report ◽  
Categorical Variables ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Multiple Methods ◽  
Once Daily ◽  
Randomized Controlled

Background: Prevalence of immunosuppressant nonadherence in renal transplant recipients is high despite negative clinical outcomes associated with nonadherence. Simplification of dosing has been demonstrated to improve adherence in renal transplant recipients as measured through electronic monitoring and self-report. Objective: The purpose of this study was to replicate and extend previous findings by measuring adherence with multiple methods in a Canadian sample. Design: The study design was a randomized controlled medication dosing trial in adult renal transplant patients. The trial length was 4 months. Setting: This study was conducted within the Solid Organ Transplant (SOT) Clinic at Vancouver General Hospital (VGH; Vancouver, Canada). Patients: A total of 46 adult renal recipients (at least 1 year post-transplant) were recruited through the SOT clinic. With 8 withdrawals, 38 individuals completed all phases of the study. Measurements: Medication adherence was measured for a period of 4 months using multiple methods, including electronic monitoring (MEMS [Medication Event Monitoring System]), pharmacy refill data (medication possession ratio [MPR]), and by self-report using the Adherence subscale of the Transplant Effects Questionnaire (TEQ). Methods: Participants were randomized to twice-daily (n = 19) or once-daily tacrolimus dosing (n = 19) and followed over a 4-month period via monthly clinic study visits. Comparisons between the treatment groups were performed using the Mann-Whitney U and chi-square tests, for continuous and categorical variables, respectively. Results: As outlined in Table 3, the once-daily dosing group showed significantly better MEMS Dose Adherence ( P = .001), whereas MEMS Timing Adherence showed a tendency toward better adherence for this group, but was not significant ( P = .052). MEMS Days Adherent ( P = .418), MPR% ( P = .123), and self-reported adherence ( P = .284) did not differ between the once- and twice-daily dosing groups when measured as continuous variables. The MPR% was significantly better for the once-daily dosing group when measured dichotomously but not continuously ( P = .044). Notably, most of those exposed to once-daily dosing (63.2%) preferred this to the twice-daily regimen. Limitations: Limitations included small sample size and short follow-up period, precluding the examination of clinical outcome differences. Conclusions: Results for dose adherence replicate the finding that dose simplification increases adherence to immunosuppressants as measured through electronic monitoring. Such an advantage for the once-daily dosing group was not seen across the 2 other electronic monitoring measurement variables (days and timing adherence). This study extends previous research by examining adherence in once versus twice-daily dosing via prescription refill data in a Canadian sample. Given the gravity of potential health outcomes associated with nonadherence, although results indicate inconsistencies in significance testing across measurement methods, the medium to large effect sizes seen in the data favoring better adherence with once-daily dosing provide an indication of the potential clinical significance of these findings. Trial registration: This study was registered with ClinicalTrials.gov (NCT01334333) on April 11, 2011.

The Relationship Between Hearing Loss Self-Management and Hearing Aid Benefit and Satisfaction

2019 ◽  
Vol 28 (2) ◽  
pp. 274-284 ◽  
Author(s):  
Elizabeth Convery ◽  
Gitte Keidser ◽  
Louise Hickson ◽  
Carly Meyer
Keyword(s):  
Decision Making ◽  
Hearing Loss ◽  
Hearing Aids ◽  
Clinical Decision Making ◽  
Hearing Aid ◽  
Well Being ◽  
Self Report ◽  
Self Management ◽  
Hearing Aid Benefit ◽  
The Relationship

Purpose Hearing loss self-management refers to the knowledge and skills people use to manage the effects of hearing loss on all aspects of their daily lives. The purpose of this study was to investigate the relationship between self-reported hearing loss self-management and hearing aid benefit and satisfaction. Method Thirty-seven adults with hearing loss, all of whom were current users of bilateral hearing aids, participated in this observational study. The participants completed self-report inventories probing their hearing loss self-management and hearing aid benefit and satisfaction. Correlation analysis was used to investigate the relationship between individual domains of hearing loss self-management and hearing aid benefit and satisfaction. Results Participants who reported better self-management of the effects of their hearing loss on their emotional well-being and social participation were more likely to report less aided listening difficulty in noisy and reverberant environments and greater satisfaction with the effect of their hearing aids on their self-image. Participants who reported better self-management in the areas of adhering to treatment, participating in shared decision making, accessing services and resources, attending appointments, and monitoring for changes in their hearing and functional status were more likely to report greater satisfaction with the sound quality and performance of their hearing aids. Conclusion Study findings highlight the potential for using information about a patient's hearing loss self-management in different domains as part of clinical decision making and management planning.

The Relationship Between Narcissism and Personality Traits of the Five-Factor-Model in Adolescents and Young Adults

2018 ◽  
Vol 46 (6) ◽  
pp. 516-522 ◽  
Author(s):  
Marc Allroggen ◽  
Peter Rehmann ◽  
Eva Schürch ◽  
Carolyn C. Morf ◽  
Michael Kölch
Keyword(s):  
Young Adults ◽  
Personality Traits ◽  
Five Factor Model ◽  
Self Report ◽  
Adolescents And Young Adults ◽  
Personality Factors ◽  
Big Five Personality ◽  
Grandiose Narcissism ◽  
Vulnerable Narcissism ◽  
The Relationship

Abstract.Narcissism is seen as a multidimensional construct that consists of two manifestations: grandiose and vulnerable narcissism. In order to define these two manifestations, their relationship to personality factors has increasingly become of interest. However, so far no studies have considered the relationship between different phenotypes of narcissism and personality factors in adolescents. Method: In a cross-sectional study, we examine a group of adolescents (n = 98; average age 16.77 years; 23.5 % female) with regard to the relationship between Big Five personality factors and pathological narcissism using self-report instruments. This group is compared to a group of young adults (n = 38; average age 19.69 years; 25.6 % female). Results: Grandiose narcissism is primarily related to low Agreeableness and Extraversion, vulnerable narcissism to Neuroticism. We do not find differences between adolescents and young adults concerning the relationship between grandiose and vulnerable narcissism and personality traits. Discussion: Vulnerable and grandiose narcissism can be well differentiated in adolescents, and the pattern does not show substantial differences compared to young adults.

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