scholarly journals Diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in Tigray, Ethiopia: retrospective observational study

2019 ◽  
Vol Volume 10 ◽  
pp. 49-55 ◽  
Author(s):  
Fikaden Berhe Hadgu ◽  
Gereziher Gebremedhin Sibhat ◽  
Letekirstos GebreEgziabher Gebretsadik
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Children And Adolescents ◽  
Diabetic Ketoacidosis ◽  
Retrospective Observational Study ◽  
Newly Diagnosed

scholarly journals A case of diabetic ketoacidosis in a patient with COVID‐19 and newly diagnosed type 1 diabetes

2021 ◽  
Vol 9 (9) ◽  
Author(s):  
Keitaro Ishii ◽  
Hirotsugu Suwanai ◽  
Taishi Saito ◽  
Naoki Motohashi ◽  
Masaru Hirayama ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Newly Diagnosed

455 INCREASED INCIDENCE AND SEVERITY OF DIABETIC KETOACIDOSIS AMONG UNINSURED CHILDREN WITH NEWLY DIAGNOSED TYPE 1 DIABETES

2005 ◽  
Vol 53 (1) ◽  
pp. S158.1-S158
Author(s):  
A. K. Maniatis ◽  
S. H. Goehrig ◽  
A. Rewers ◽  
P. Walravens ◽  
G. J. Klingensmith
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Newly Diagnosed ◽  
Uninsured Children

Frequency, clinical characteristics, biochemical findings and outcomes of DKA at the onset of type-1 DM in young children and adolescents living in a developing country – an experience from a pediatric emergency department

2019 ◽  
Vol 32 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Amna Jawaid ◽  
Arjumand Sohaila ◽  
Nadia Mohammad ◽  
Unaib Rabbani
Keyword(s):  
Diabetes Mellitus ◽  
Emergency Department ◽  
Developing Countries ◽  
Type 1 Diabetes ◽  
Mortality Rate ◽  
Children And Adolescents ◽  
Diabetic Ketoacidosis ◽  
Clinical Characteristics ◽  
Incidence And Mortality

Abstract Background As per the International Society for Pediatrics and Adolescent Diabetes (ISPAD) census, diabetic ketoacidosis (DKA) is the most frequent cause of diabetes-related death. In developing countries, DKA-related mortality rate ranges from 6% to 24% (Onyiriuka AN, Ifebi E. Ketoacidosis at diagnosis of type 1 diabetes in children and adolescents: frequency and clinical characteristics. J Diabetes Metab Disord 2013;12:47) in contrast to 0.15%–0.31% in the Western world (Poovazhagi V. Risk factors for mortality in children with diabetic ketoacidosis from developing countries. World J Diabetes 2014;5:932–93.). In developing countries like Pakistan, the situation is more perplexing owing to uncertain or under-reported statistics about the spectrum of the disease and its prevalence, coupled with limited access to medical care and experts as well as less awareness. These limitations restrict our ability to develop interventions that are patient-centered. Our main objective was to determine the severity, clinical features, bio-chemical findings and outcomes of DKA in children aged 1 month to 16 years. Subjects and methods This retrospective study included the analysis of medical and laboratory records from patients’ medical charts and the electronic database of all children aged 1 month to 16 years with newly diagnosed type-1 diabetes mellitus (T1DM) complicated with ketoacidosis, who presented to the emergency department (ED) at the Aga Khan University Hospital (AKUH), between January 2009 and December 2014. Results Diabetes mellitus complicated with DKA was the predominant diagnosis (n=113 [75.83%]) among endocrine diseases in children visiting the ED. Our study witnessed an increase in the incidence of DKA particularly after 5 years of age, with more severity in females. In our study, the mortality rate was 3.4%. Conclusions Considering the high incidence and mortality rate, it is emphasized that DKA should be considered in differential diagnosis. An awareness campaign for both general pediatricians and physicians as well as for the public is needed for better outcomes.

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