scholarly journals Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation

2013 ◽  
pp. 189 ◽  
Author(s):  
Xuan Zhang ◽  
Duan ◽  
Zhao ◽  
Ren ◽  
Wang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Glioma Cell ◽  
C6 Glioma ◽  
In Vivo Evaluation ◽  
C6 Glioma Cell

Suppressive effects of swainsonine on C6 glioma cell in vitro and in vivo

Phytomedicine ◽  
2009 ◽  
Vol 16 (11) ◽  
pp. 1070-1074 ◽  
Author(s):  
Ji-Yuan Sun ◽  
Hao Yang ◽  
Shan Miao ◽  
Ji-Peng Li ◽  
Si-Wang Wang ◽  
...  
Keyword(s):  
Glioma Cell ◽  
C6 Glioma ◽  
C6 Glioma Cell

Effects of fractal surface on C6 glioma cell morphogenesis and differentiation in vitro

Biomaterials ◽  
2010 ◽  
Vol 31 (24) ◽  
pp. 6201-6206 ◽  
Author(s):  
Ping Wang ◽  
Lei Li ◽  
Cheng Zhang ◽  
Qunfang Lei ◽  
Wenjun Fang
Keyword(s):  
Glioma Cell ◽  
C6 Glioma ◽  
Cell Morphogenesis ◽  
Fractal Surface ◽  
C6 Glioma Cell

Isoproterenol-induced selective phosphorylative modification in vivo of rat C6 glioma cell histones

1980 ◽  
Vol 96 (3) ◽  
pp. 1253-1260 ◽  
Author(s):  
Janie J. Harrison ◽  
Peter Suter ◽  
Susan Suter ◽  
Richard A. Jungmann
Keyword(s):  
Glioma Cell ◽  
C6 Glioma ◽  
C6 Glioma Cell ◽  
Rat C6 Glioma

Radiosensitization of C6 glioma by thymidine and 41.8°C hyperthermia

1990 ◽  
Vol 72 (5) ◽  
pp. 782-785 ◽  
Author(s):  
Justin D. Cohen ◽  
H. Ian Robins ◽  
Manucher J. Javid
Keyword(s):  
Cell Survival ◽  
Cell Line ◽  
Untreated Control ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
C6 Glioma ◽  
Content Type ◽  
C6 Glioma Cell ◽  
Fine Print

✓ The cytotoxic, antiproliferative, and radiosensitizing effects of thymidine (a nucleoside metabolite) were studied using the C6 glioma cell line in vitro. Radiosensitization by a combination of thymidine and 41.8°C hyperthermia was also evaluated. Thymidine concentrations above 100 µg/ml completely inhibited C6 proliferation while concentrations of 100 to 1000 µg/ml (for up to 24 hours) decreased C6 cell survival to as little as 7.4% compared to untreated control cells. Radiosensitivity was enhanced by the administration of thymidine alone (400 µg/ml × 24 hours before irradiation); sensitization by 41.8°C hyperthermia alone (1 hour ending immediately before irradiation) was less pronounced. Thymidine and hyperthermia together produced greater radiosensitization than did heat alone or thymidine alone. These data support the further investigation of thymidine as a neuro-oncology radiosensitizer.

scholarly journals Thymosin Fraction 5 Inhibits the Proliferation of the Rat Neuroendocrine MMQ Pituitary Adenoma and C6 Glioma Cell Lines in Vitro*

Endocrinology ◽  
1998 ◽  
Vol 139 (4) ◽  
pp. 2155-2162 ◽  
Author(s):  
Bryan L. Spangelo ◽  
Derald D. Farrimond ◽  
Mahesh Thapa ◽  
Charles M. Bulathsinghala ◽  
Kay-Lynn Bowman ◽  
...  
Keyword(s):  
Pituitary Adenoma ◽  
Cell Lines ◽  
Glioma Cell ◽  
C6 Glioma ◽  
C6 Glioma Cell ◽  
Glioma Cell Lines

Intravenous administration of trans-resveratrol-loaded TPGS-coated solid lipid nanoparticles for prolonged systemic circulation, passive brain targeting and improved in vitro cytotoxicity against C6 glioma cell lines

RSC Advances ◽  
2016 ◽  
Vol 6 (55) ◽  
pp. 50336-50348 ◽  
Author(s):  
Mahalingam Rajamanickam Vijayakumar ◽  
Lakshmi Kumari ◽  
Krishna Kumar Patel ◽  
Parameswara Rao Vuddanda ◽  
Kiran Yellappa Vajanthri ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Glioma Cell ◽  
Red Wine ◽  
Systemic Circulation ◽  
Lipid Nanoparticles ◽  
C6 Glioma ◽  
In Vitro Cytotoxicity ◽  
Brain Targeting ◽  
C6 Glioma Cell

trans-Resveratrol (RSV), a natural molecule isolated from red wine, is widely known for several therapeutic potentials.

scholarly journals The Effects of Combined SarCNU and Ganglioside Treatment of Growth of C6 Glioma Cell Cultures

1998 ◽  
Vol 1 (1) ◽  
pp. 20-23
Author(s):  
Adlija Jevrić-Čaušević
Keyword(s):  
Cell Culture ◽  
Glioma Cell ◽  
C6 Glioma ◽  
Neuroprotective Effects ◽  
Antiproliferative Effects ◽  
Protein Assay ◽  
C6 Glioma Cell ◽  
Two Agents ◽  
Cytotoxicity Effects

In vitro antiproliferative effects of SarCNU and GMI ganglioside were tested in different concentration ratios in C6 glioma cell culture. Based on MTT assay and a protein assay, cytotoxicity of each agent separately and the two agents combined was tested. When the cells were treated with different concentrations of ganglioside ranging from 10-’ to 10-2, the number of viable cells decreased highly on days two and seven, regardless of the concentration of the agent applied. SarCNU, as expected, has caused antiproliferative effects which highly correlated with the concentration of the agent tested. When the C6 glioma cell culture was treated with the two agents combined in the optimal concentration causing the above mentioned cytotoxicity, effects observed did not correlate with those observed for each agent alone, suggesting in this case the expression of highly neuroprotective effects of ganglioside GMI.

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