scholarly journals Vitamin D3 Supplementation and Stress Fractures in High-Risk Collegiate Athletes – A Pilot Study

2020 ◽  
Vol Volume 12 ◽  
pp. 9-17 ◽  
Author(s):  
Kevin Williams ◽  
Christian Askew ◽  
Christopher Mazoue ◽  
Jeffrey Guy ◽  
Toni M Torres-McGehee ◽  
...  
Keyword(s):  
Pilot Study ◽  
High Risk ◽  
Vitamin D3 ◽  
Collegiate Athletes ◽  
Stress Fractures ◽  
Vitamin D3 Supplementation

Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes

2017 ◽  
Vol 49 (5S) ◽  
pp. 952
Author(s):  
Kevin A. Williams ◽  
Christian Askew ◽  
Christopher Mazoue ◽  
Jeffrey Guy ◽  
Toni M. Torres-McGehee ◽  
...  
Keyword(s):  
High Risk ◽  
Stress Fracture ◽  
Vitamin D3 ◽  
Collegiate Athletes ◽  
Vitamin D3 Supplementation

Open-label pilot study on vitamin D3 supplementation for antipsychotic-associated metabolic anomalies

2013 ◽  
Vol 28 (5) ◽  
pp. 275-282 ◽  
Author(s):  
Neelam Thakurathi ◽  
Shannon Stock ◽  
Claire E. Oppenheim ◽  
Christina P.C. Borba ◽  
Brenda Vincenzi ◽  
...  
Keyword(s):  
Pilot Study ◽  
Vitamin D3 ◽  
Open Label ◽  
Vitamin D3 Supplementation

scholarly journals Vitamin D3 Supplementation Improved Physical Performance in Healthy Older Adults in Japan: A Pilot Study

Health ◽  
2018 ◽  
Vol 10 (09) ◽  
pp. 1200-1209
Author(s):  
Noboru Hasegawa ◽  
Miyako Mochizuki ◽  
Mayumi Kato ◽  
Nobuko Shimizu ◽  
Takako Yamada
Keyword(s):  
Older Adults ◽  
Pilot Study ◽  
Physical Performance ◽  
Vitamin D3 ◽  
Healthy Older Adults ◽  
Vitamin D3 Supplementation

scholarly journals The Effects of Cholecalciferol Supplementation on Vitamin D Status Among a Diverse Population of Collegiate Basketball Athletes: A Quasi-Experimental Trial

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 370 ◽  
Author(s):  
Nicole M. Sekel ◽  
Sina Gallo ◽  
Jennifer Fields ◽  
Andrew R. Jagim ◽  
Tammy Wagner ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D3 ◽  
Injury Risk ◽  
Collegiate Athletes ◽  
Vitamin D Status ◽  
Experimental Trial ◽  
Quasi Experimental ◽  
Vitamin D3 Supplementation ◽  
Collegiate Basketball ◽  
Cholecalciferol Supplementation

Vitamin D may play a role in performance and injury risk, yet the required supplementation dosage for collegiate athletes is unclear. The objective of this study was to define the dosage of vitamin D3 supplementation required to beneficially affect serum 25-hydroxyvitamin D (25(OH)D) among a sample of collegiate basketball athletes. This was a quasi-experimental trial, participants were allocated to one of three groups of vitamin D3 daily at the beginning of pre-season training and dependent upon their baseline vitamin D status as follows: insufficient (<75 nmol/L) to 10,000 IU, sufficient (75–125 nmol/L) to 5000 IU and optimal (>125 nmol/L) to no supplementation. Follow-up assessments were completed ~ 5 months later in post season. The majority (n = 13) were allocated to 10,000 IU vs. n = 5 to 5000 IU and n = 2 to no supplementation. The 10,000 IU group showed the greatest change (35.0 ± 27.0 nmol/L) vs. the 5000 IU group (−9.3 ± 9.6 nmol/L) and no supplementation group (−41.6 ± 11.7 nmol/L, p < 0.01). Only 1 participant reached optimal status in the 10,000 IU group. In conclusion, a daily dosage of 10,000 IU vitamin D3 supplementation mitigated the high prevalence of vitamin D deficiency among collegiate basketball players but was insufficient for all to reach sufficient levels.

scholarly journals Vitamin D in human serum and adipose tissue after supplementation

2020 ◽  
Vol 113 (1) ◽  
pp. 83-91
Author(s):  
Cora M Best ◽  
Devon V Riley ◽  
Thomas J Laha ◽  
Hannah Pflaum ◽  
Leila R Zelnick ◽  
...  
Keyword(s):  
Vitamin D ◽  
Adipose Tissue ◽  
Pilot Study ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Absolute Difference ◽  
Hydroxyvitamin D ◽  
Liquid Chromatography Tandem Mass ◽  
Vitamin D3 Supplementation ◽  
Tissue Vitamin

ABSTRACT Background Serum 25-hydroxyvitamin D [25(OH)D] concentration is an indicator of vitamin D exposure, but it is also influenced by clinical characteristics that affect 25(OH)D production and clearance. Vitamin D is the precursor to 25(OH)D but is analytically challenging to measure in biological specimens. Objectives We aimed to develop and validate a liquid chromatography–tandem mass spectrometry (LC-MS/MS) method for quantification of vitamins D3 and D2 in serum and to explore the potential of circulating vitamin D as a biomarker of exposure in supplementation trials. Methods The method was validated using guideline C62-A from the Clinical and Laboratory Standards Institute and was applied in 2 pilot clinical trials of oral vitamin D3 supplementation. Pilot study 1 included 22 adults randomly assigned to placebo or 2000 IU/d. Blood was collected at baseline, 1, 3, 6, and 12 mo. Pilot study 2 included 15 adults randomly assigned to 2000 or 4000 IU/d. Blood and subcutaneous (SUBQ) adipose tissue were collected at baseline and 3 mo. Results In study 1, mean change (baseline to 3 mo) in serum vitamin D3 was −0.1 ng/mL in the placebo group and 6.8 ng/mL in the 2000 IU/d group (absolute difference: 6.9; 95% CI: 4.5, 9.3 ng/mL). In study 2, mean change (baseline to 3 mo) in serum vitamin D3 was 10.4 ng/mL in the 2000 IU/d group and 22.2 ng/mL in the 4000 IU/d group (fold difference: 2.15; 95% CI: 1.40, 3.37). Serum and adipose tissue vitamin D3 concentrations were correlated, and the dose-response of vitamin D3 in adipose mirrored that in serum. Conclusions We validated a sensitive, robust, and high-throughput LC-MS/MS method to quantify vitamins D3 and D2 in serum. Serum and SUBQ adipose tissue vitamin D3 concentrations increased proportionally to dose with 3 mo of daily supplementation. These trials were registered at clinicaltrials.gov as NCT00552409 (pilot study 1) and NCT01477034 (pilot study 2).

Vitamin D2 versus vitamin D3 supplementation in hemodialysis patients: a comparative pilot study

2012 ◽  
Vol 26 (1) ◽  
pp. 152-157 ◽  
Author(s):  
Maïté Daroux ◽  
Milhad Shenouda ◽  
Jean-Louis Bacri ◽  
Vincent Lemaitre ◽  
Philippe Vanhille ◽  
...  
Keyword(s):  
Pilot Study ◽  
Vitamin D3 ◽  
Hemodialysis Patients ◽  
Vitamin D2 ◽  
Vitamin D3 Supplementation

Effect of vitamin D3 supplementation on the pharmacokinetics of digoxin - a pilot study

2011 ◽  
Vol 26 (4) ◽  
pp. 543-548 ◽  
Author(s):  
Bhavani P. Kota ◽  
Mohi I. M. Abdul ◽  
John D. Allen ◽  
Madan Kalagara ◽  
Basil D. Roufogalis
Keyword(s):  
Pilot Study ◽  
Vitamin D3 ◽  
Vitamin D3 Supplementation
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