scholarly journals Efficacy of cultivated corneal epithelial stem cells for ocular surface reconstruction

2012 ◽  
pp. 1483 ◽  
Author(s):  
Suksri Chotikavanich ◽  
Prabhasawat ◽  
Pattama Ekpo ◽  
Uiprasertkul ◽  
Nattaporn Tesavibul
Keyword(s):  
Stem Cells ◽  
Surface Reconstruction ◽  
Ocular Surface ◽  
Epithelial Stem Cells ◽  
Corneal Epithelial ◽  
Ocular Surface Reconstruction

Human Anterior Lens Capsule as a Biologic Substrate for the Ex Vivo Expansion of Limbal Stem Cells in Ocular Surface Reconstruction

Cornea ◽  
2007 ◽  
Vol 26 (4) ◽  
pp. 473-478 ◽  
Author(s):  
Ahmed Galal ◽  
Juan J Perez-Santonja ◽  
Jose Luis Rodriguez-Prats ◽  
Marta Abad ◽  
Jorge Alio
Keyword(s):  
Stem Cells ◽  
Surface Reconstruction ◽  
Ocular Surface ◽  
Ex Vivo ◽  
Ex Vivo Expansion ◽  
Lens Capsule ◽  
Limbal Stem Cells ◽  
Ocular Surface Reconstruction ◽  
Anterior Lens Capsule

Amniotic Membrane Transplantation for Ocular Surface Reconstruction

2001 ◽  
Vol 21 (4) ◽  
pp. 481-489 ◽  
Author(s):  
S.C.G. Tseng
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Transforming Growth Factor ◽  
Ease Of Use ◽  
Myoblast Differentiation ◽  
Amniotic Membrane Transplantation ◽  
Clinical Effects ◽  
Epithelial Stem Cells ◽  
Ocular Surface Reconstruction

The use of amniotic membrane (or amnion) for transplantation as graft in ocular surface reconstruction is reviewed. This technique has become widespread because of the availability of the amnion, convenience and ease of use, and high and reproducible success rates. The mechanisms of action of the transplantation are varied and include the prolongation and clonogenic maintenance of epithelial progenitor cells, promotion of goblet and non-goblet cell differentiation, exclusion of inflammatory cells with anti-protease activities, suppression of Transforming Growth Factor β signaling and myoblast differentiation of normal fibroblasts. The observed clinical effects include facilitation of epithelialization, maintenance of normal phenotypes, and reduction of inflammation, vascularization and scarring. Amniotic membrane transplantation is being increasingly used as graft for various conjunctival and corneal diseases and as a patch in cases of chemical and thermal burns, refractory and recalcitrant keratitis, and most recently as an excellent substrate for expanding epithelial stem cells ex vivo.

TREATMENT OF PERSISTENT CORNEAL EPITHELIAL DEFECTS AND OCULAR SURFACE RECONSTRUCTION WITH AMNIOTIC MEMBRANE

Cornea ◽  
1998 ◽  
Vol 17 (2) ◽  
pp. 248
Author(s):  
Sabrina D. Shah-Desai ◽  
Nabil E. Habib ◽  
Wilbert K. Hoe ◽  
Sheraz M. Daya
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Corneal Epithelial ◽  
Ocular Surface Reconstruction

A Fibrin-based Bioengineered Ocular Surface With Human Corneal Epithelial Stem Cells

Cornea ◽  
2002 ◽  
Vol 21 (5) ◽  
pp. 505-510 ◽  
Author(s):  
Bin Han ◽  
Ivan R. Schwab ◽  
Trista K. Madsen ◽  
R. Rivkah Isseroff
Keyword(s):  
Stem Cells ◽  
Ocular Surface ◽  
Epithelial Stem Cells ◽  
Corneal Epithelial
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