scholarly journals Treatment Success Across Different Levels of Preoperative Disease Burden: Stratified Two-Year Outcomes from the Pivotal Trial of iStent inject® Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract

2021 ◽  
Vol Volume 15 ◽  
pp. 3231-3240
Author(s):  
Inder Paul Singh ◽  
Steven Sarkisian ◽  
Dana Hornbeak ◽  
L Jay Katz ◽  
Thomas Samuelson
Ophthalmology ◽  
2020 ◽  
Vol 127 (2) ◽  
pp. e14-e15
Author(s):  
Karina Carvalho Melo Araújo ◽  
Elson Cabral Velanes Neto ◽  
Ana Luiza Bassoli Scoralick ◽  
Fabio Nishimura Kanadani ◽  
Tiago Santos Prata

Ophthalmology ◽  
2019 ◽  
Vol 126 (6) ◽  
pp. 811-821 ◽  
Author(s):  
Thomas W. Samuelson ◽  
Steven R. Sarkisian ◽  
David M. Lubeck ◽  
Michael C. Stiles ◽  
Yi-Jing Duh ◽  
...  

2021 ◽  
pp. 112067212110006
Author(s):  
Jeremy Hu YW ◽  
Bryan Ang CH ◽  
Ivan O’Neill C. Tecson ◽  
John Kan Tsia-Chuen ◽  
Leonard Yip WL

Purpose: To evaluate the safety and efficacy of the iStent inject device combined with phacoemulsification in Asian eyes with primary open angle glaucoma. Methods: A retrospective study of combined phacoemulsification and iStent inject surgeries performed in a single institution from July 2017 to August 2019 on patients with co-existing cataracts and primary open angle glaucoma (POAG). Outcome measures included best-corrected visual acuity, intraocular pressure (IOP), number of glaucoma eyedrop medications, and surgical complications. Results: A total of 95 eyes were included. Majority of subjects were male (59, 62.1%) and Chinese (83, 87.4%). Mean age was 74.7 ± 8.7 years. Pre-operatively, mean IOP was 16.2 ± 4.3 mmHg and number of medications was 1.9 ± 0.9. Significant post-operative reduction in mean IOP was observed at all timepoints – post-operative month (POM)1: 3.0 ± 5.6 mmHg reduction ( n = 95, p < 0.05); POM3: 1.6 ± 3.8 mmHg ( n = 66, p < 0.05); POM6: 1.8 ± 4.7 mmHg ( n = 55, p < 0.05); POM12: 1.3 ± 4.2 mmHg ( n = 48) ( p < 0.05). The number of glaucoma medications was also reduced from a mean of 1.9 ± 0.8 to 0.6 ± 1.0 at POM12 ( p < 0.05). Intraoperatively, one case of malignant glaucoma occurred. Post operatively, implant obstruction by iris was observed in two eyes post-operatively requiring iridoplasty. One case of cystoid macular edema and one case of drop in visual acuity due to glaucoma progression was/were also observed. Conclusion: Asian eyes undergoing combined phacoemulsification and iStent inject surgery demonstrate a significant and sustained reduction in both IOP and number of glaucoma medications. Overall, there is a good safety profile for iStent inject.


2019 ◽  
Vol 47 (7) ◽  
pp. 898-903 ◽  
Author(s):  
Joobin Hooshmand ◽  
Philip Rothschild ◽  
Penny Allen ◽  
Nathan M. Kerr ◽  
Brendan J. Vote ◽  
...  

2019 ◽  
Vol 22 ◽  
pp. S671
Author(s):  
A. Igarashi ◽  
H. Falvey ◽  
A. Chu ◽  
M. Ueyama ◽  
J. Zhou ◽  
...  

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